Results 1 to 10 of about 144,829 (355)
Cell-based glycan arrays for probing glycan–glycan binding protein interactions [PDF]
Nature Communications, 2018 Glycans, interaction platforms protruding from the surface of cells, are hard to study due to their diverse architecture. Here, the authors present a method to obtain cells carrying defined glycans, which can then be used to find proteins specifically ...
Jennie Grace Briard +4 more
doaj +4 more sources
A glycan gate controls opening of the SARS-CoV-2 spike protein
Nature Chemistry, 2021 SARS-CoV-2 infection is controlled by the opening of the spike protein receptor binding domain (RBD), which transitions from a glycan-shielded ‘down’ to an exposed ‘up’ state to bind the human angiotensin-converting enzyme 2 receptor and infect cells ...
Terra Sztain +2 more
exaly +2 more sources
Vulnerabilities in coronavirus glycan shields despite extensive glycosylation
Nature Communications, 2020 Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) coronaviruses (CoVs) are zoonotic pathogens with high fatality rates and pandemic potential.
Yasunori Watanabe +2 more
exaly +2 more sources
The challenges of glycan recognition with natural and artificial receptors
Chemical Society Reviews, 2019 Glycans - simple or complex carbohydrates - play key roles as recognition determinants and modulators of numerous physiological and pathological processes.
Stefano Tommasone +2 more
exaly +2 more sources
Cellular & Molecular Immunology, 2023 The immune system is coordinated by an intricate network of stimulatory and inhibitory circuits that regulate host responses against endogenous and exogenous insults.
S. Pinho +3 more
semanticscholar +1 more source
How glycan metabolism shapes the human gut microbiota
Nature Reviews Microbiology, 2012 Nicole M Koropatkin, Eric C Martens
exaly +2 more sources
Nature Communications, 2022 Glycopeptides with unusual glycans or poor peptide backbone fragmentation in tandem mass spectrometry are unaccounted for in typical site-specific glycoproteomics analysis and thus remain unidentified.
Zheng Fang +9 more
semanticscholar +1 more source
BMC Microbiology, 2021 Background The abundance of glycomics data that have accumulated has led to the development of many useful databases to aid in the understanding of the function of the glycans and their impact on cellular activity. At the same time, the endeavor for data
Sunmyoung Lee +2 more
doaj +1 more source
BMC Chemistry, 2021 With the increasing demand for antimicrobial agents and the spread of antibiotic resistance in pathogens, the exploitation of plant oils to partly replace antibiotic emerges as an important source of fine chemicals, functional food utility and ...
Ahmed M. Senan +8 more
doaj +1 more source
Changes in protein N-glycosylation during the fruit development and ripening in melting-type peach
Food Materials Research, 2021 The posttranslational modification of proteins with complex carbohydrate moieties (glycosylation) regulates the process of fruit ripening. Exoglycosidases are enzymes that can trim this protein glycosylation and are therefore considered to be important ...
Ting Wang +3 more
doaj +1 more source