Results 11 to 20 of about 172,036 (354)
Multivalent glycan arrays [PDF]
Faraday Discussions, 2019 Glycan microarrays have become a powerful technology to study biological processes, such as cell–cell interaction, inflammation, and infections. Yet, several challenges, especially in multivalent display, remain.
Bordoni, Vittorio +5 more
core +5 more sources
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques [PDF]
Nature, 2019 Broadly neutralizing monoclonal antibodies protect against infection with HIV-1 in animal models, suggesting that a vaccine that elicits these antibodies would be protective in humans.
Amelia Escolano +2 more
exaly +2 more sources
Glycan Profile Alterations in Vaginitis and Their Role in Pathogen-Host Interactions. [PDF]
Polish Journal of MicrobiologyGlycosylation is one of the post-translational modifications that occur in the endoplasmic reticulum (ER)-Golgi pathway. During enzymatic glycosylation, glycosidic linkages form between saccharides, proteins and lipids.
Bodaszewska-Lubaś Małgorzata
doaj +2 more sources
Nanomaterials, 2020 This review paper comprehensively summarizes advances made in the design of glycan nanobiosensors using diverse forms of nanomaterials. In particular, the paper covers the application of gold nanoparticles, quantum dots, magnetic nanoparticles, carbon nanoparticles, hybrid types of nanoparticles, proteins as nanoscaffolds and various nanoscale-based ...
Filip Kveton +3 more
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BMC Microbiology, 2021 Background The abundance of glycomics data that have accumulated has led to the development of many useful databases to aid in the understanding of the function of the glycans and their impact on cellular activity. At the same time, the endeavor for data
Sunmyoung Lee +2 more
doaj +1 more source
BMC Chemistry, 2021 With the increasing demand for antimicrobial agents and the spread of antibiotic resistance in pathogens, the exploitation of plant oils to partly replace antibiotic emerges as an important source of fine chemicals, functional food utility and ...
Ahmed M. Senan +8 more
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Changes in protein N-glycosylation during the fruit development and ripening in melting-type peach
Food Materials Research, 2021 The posttranslational modification of proteins with complex carbohydrate moieties (glycosylation) regulates the process of fruit ripening. Exoglycosidases are enzymes that can trim this protein glycosylation and are therefore considered to be important ...
Ting Wang +3 more
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Glycan Fingerprints: Calculating Diversity in Glycan Libraries [PDF]
ACS Chemical Biology, 2012 Carbohydrate libraries printed in glycan micorarray format have had a great impact on the high-throughput analysis of the specificity of a wide range of mammalian, plant, and bacterial lectins. Chemical and chemo-enzymatic synthesis allows the construction of diverse glycan libraries but requires substantial effort and resources.
Rademacher, C., Paulson, J.
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Cell-based glycan arrays for probing glycan–glycan binding protein interactions [PDF]
Nature Communications, 2018 AbstractGlycan microarrays provide a high-throughput means of profiling the interactions of glycan-binding proteins with their ligands. However, the construction of current glycan microarray platforms is time consuming and expensive. Here, we report a fast and cost-effective method for the assembly of cell-based glycan arrays to probe glycan–glycan ...
Jennie Grace Briard +4 more
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Novel chemical- and protein-mediated methods for glucosamine detection
Food Materials Research, 2022 We describe two novel approaches for the determination of glucosamine (GlcN). The first approach is based on the chemical derivatization of GlcN with the non-fluorophor 1,3-diphenyl-1,3-propanedione (DPPD), which results in a condensation product with ...
Linshu Chen +6 more
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