Results 11 to 20 of about 144,829 (355)
Synthesis of a glycan hairpin [PDF]
Nature Chemistry, 2023 AbstractThe primary sequence of a biopolymer encodes the essential information for folding, permitting to carry out sophisticated functions. Inspired by natural biopolymers, peptide and nucleic acid sequences have been designed to adopt particular three-dimensional (3D) shapes and programmed to exert specific functions.
Giulio Fittolani +7 more
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Nanomaterials, 2020 This review paper comprehensively summarizes advances made in the design of glycan nanobiosensors using diverse forms of nanomaterials. In particular, the paper covers the application of gold nanoparticles, quantum dots, magnetic nanoparticles, carbon nanoparticles, hybrid types of nanoparticles, proteins as nanoscaffolds and various nanoscale-based ...
Filip Kveton +3 more
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Glycans and Glycan-Binding Proteins in Atherosclerosis [PDF]
Thrombosis and Haemostasis, 2019 AbstractComplex glycans are readily accessible on the endothelium and on cell and plasma components. They interact with glycan-binding proteins which translate their structure into function. Advanced analytical tools are available to investigate their structure and functional interactions.
Veit Eckardt +2 more
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Science Immunology, 2018 The gut commensal bacterium Bifidobacterium bifidum promotes immune tolerance by facilitating the induction of colonic regulatory T cells. See related Research Article by Verma et al .
Katherine A. Kaiser, Nicholas Arpaia
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Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues
Nature Communications, 2022 Glycosylation is essential to brain development and function, but prior studies have often been limited to a single analytical technique and excluded region- and sex-specific analyses.
Sarah E. Williams +9 more
semanticscholar +1 more source
Probing the binding specificities of human Siglecs by cell-based glycan arrays
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Siglecs are immunomodulatory receptors that recognize sialic acid–carrying glycans with important functions in immunity. However, many of their natural ligands are poorly defined. We generated a cell-based glycan array comprised of a library
C. Büll +17 more
semanticscholar +1 more source
Glycan profiling of the gut microbiota by Glycan-seq
ISME Communications, 2022 Abstract Bacterial glycans modulate the cross talk between the gut microbiota and its host. However, little is known about these glycans because of the lack of appropriate technology to study them. In this study, we applied Glycan-seq technology for glycan profiling of the intact gut microbiota of mice.
Lalhaba Oinam +2 more
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Mucin-Type O-Glycosylation in the Drosophila Nervous System
Frontiers in Neuroanatomy, 2021 Mucin-type O-glycosylation, a predominant type of O-glycosylation, is an evolutionarily conserved posttranslational modification in animals. Mucin-type O-glycans are often found on mucins in the mucous membranes of the digestive tract.
Kazuyoshi Itoh +2 more
doaj +1 more source
Site-specific glycan analysis of the SARS-CoV-2 spike
Science, 2020 SARS-CoV-2 spike protein, elaborated Vaccine development for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is focused on the trimeric spike protein that initiates infection.
Yasunori Watanabe +4 more
semanticscholar +1 more source
Novel chemical- and protein-mediated methods for glucosamine detection
Food Materials Research, 2022 We describe two novel approaches for the determination of glucosamine (GlcN). The first approach is based on the chemical derivatization of GlcN with the non-fluorophor 1,3-diphenyl-1,3-propanedione (DPPD), which results in a condensation product with ...
Linshu Chen +6 more
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