The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie +5 more
wiley +1 more source
A neural glycan HNK-1 is transferred to recipient cells via small extracellular vesicles. [PDF]
Tokoro Y, Kizuka Y.
europepmc +1 more source
Increased Glycan Chain Length Distribution and Decreased Susceptibility to Moenomycin in a Vancomycin-Resistant Staphylococcus aureus Mutant [PDF]
Hitoshi Komatsuzawa +7 more
openalex +1 more source
CRPPA exon 6–9 deletion as a founder mutation in Chinese patients with dystroglycanopathy
Analysis of sixteen Chinese dystroglycanopathy patients reveals a founder mutation (CRPPA exon 6–9 deletion) in 25% of cases and expands the phenotypic spectrum from severe muscle‐eye‐brain disease to limb‐girdle muscular dystrophy. ABSTRACT Importance Dystroglycanopathies (DGPs) are a group of muscular dystrophies with abnormal glycosylation of ...
Jihang Luo +18 more
wiley +1 more source
Efficient mucin O-glycan degradation by specific mucin degrading intestinal bacteria: towards understanding enzyme-glycan interactions. [PDF]
de Ram C +10 more
europepmc +1 more source
Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto +2 more
wiley +1 more source
The Biological Basis and Analyses of N-Glycan Microheterogeneity. [PDF]
Adams TM +3 more
europepmc +1 more source
Glycan Covalent Targeting Chimera‐Based T‐Cell Glycoengineering for Boosting Immunotherapy [PDF]
Yichun Wang +13 more
openalex +1 more source
Biomolecular Interaction Prediction in the Pre‐ and Post‐AlphaFold Era: The 8th CAPRI Evaluation
ABSTRACT We report on the 8th CAPRI Evaluation period, capturing the assessment of CAPRI Rounds 47 to 55 (excluding the CASP and COVID‐related Rounds), which have witnessed the transition to AI‐driven prediction tools such as AlphaFold and related alternatives. The prediction Rounds in this evaluation are characterized by a high level of difficulty due
Marc F. Lensink +5 more
wiley +1 more source
GlyContact analyzes glycan 3D structures at scale. [PDF]
Thomès L, Joeres R, Akdeniz Z, Bojar D.
europepmc +1 more source

