The N-Glycans Determine the Differential Blood Clearance and Hepatic Uptake of Human Immunoglobulin (Ig)a1 and Iga2 Isotypes [PDF]
Abdalla Rifai+3 more
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<i>Shigella</i> Mutant with Truncated O-Antigen as an Enteric Multi-Pathogen Vaccine Platform. [PDF]
Kim JO+8 more
europepmc +1 more source
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu+4 more
wiley +1 more source
Structural Analysis of Murine Zona Pellucida Glycans [PDF]
Richard L. Easton+6 more
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Effect of glycosylation on protein folding: From biological roles to chemical protein synthesis. [PDF]
Hao C, Zou Q, Bai X, Shi W.
europepmc +1 more source
Antithrombin: Deficiency, Diversity, and the Future of Diagnostics
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt+2 more
wiley +1 more source
Structural characterization of the N-glycans of Dictyocaulus viviparus: discovery of the Lewisx structure in a nematode [PDF]
Stuart M. Haslam
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Integration of RNAseq transcriptomics and <i>N</i>-glycomics reveal biosynthetic pathways and predict structure-specific <i>N</i>-glycan expression. [PDF]
Alvarez MRS+8 more
europepmc +1 more source
Recent clinical trials transplanted gene‐edited pig hearts, kidneys, and a liver into eight human patients, demonstrating xenotransplantation's potential to address organ shortages. While showing promise, outcomes varied, highlighting key challenges including immune rejection and managing patient comorbidities, requiring further optimization.
Lisha Mou, Zuhui Pu, David K. C. Cooper
wiley +1 more source
Roles of Individual N-Glycans for ATP Potency and Expression of the Rat P2X1 Receptor [PDF]
Jürgen Rettinger+2 more
openalex +1 more source