Results 281 to 290 of about 144,829 (355)

Mechanism elucidation of cell‐selective fluorescent probes

Smart Molecules, EarlyView.
This perspective outlines five mechanistic strategies—Protein‐oriented, carbohydrate‐oriented, lipid‐oriented, gating‐oriented, and metabolism‐oriented live‐cell distinctions—for achieving cell‐selective fluorescence in live‐cell imaging. By classifying probes based on their interactions with proteins, carbohydrates, lipids, transporters, or metabolic ...
Sourav Sarkar, Young‐Tae Chang
wiley   +1 more source

RNA-associated glycoconjugates highlight potential ambiguities in glycoRNA analysis. [PDF]

Exp Mol Med
Kim S, Li Z, Choi YG, Janssen K, Langenbach JH, van den Brink DJ, Büll C, Joshi BS, Pomorski A, Raz V, Tanenbaum ME, Miesen P, Joo C.   +12 more
europepmc   +1 more source

Exosome‐Based Cartilage‐Targeted Delivery System: Strategies and Applications

Small Science, EarlyView.
Construction strategies and applications of cartilage‐targeting exosomes. With the ageing of the global population, cartilage‐related diseases, such as osteoarthritis (OA) and intervertebral disc degeneration (IVDD), have increasingly become significant social problems threatening human health. Therefore, targeted therapy for cartilage is becoming more
Yao Wang, Bo Chen, Haodong Zhu, Zhenyu Sun   +3 more
wiley   +1 more source

Shaping the Glycan Landscape: Hidden Relationships between Linkage and Ring Distortions Induced by Carbohydrate-Active Enzymes. [PDF]

J Am Chem Soc
Grothaus IL, Spellerberg P, Rovira C, Colombi Ciacchi L.   +3 more
europepmc   +1 more source

Synthesis of Boronic Acid‐Functionalized Core–Shell Mesoporous Silica–TiO2 Nanocomposite for Specific Enrichment of Glycopeptides From Biological Samples

Small Methods, EarlyView.
The schematic illustrates a workflow showing the current investigation using a boronic acid‐functionalized core–shell mesoporous silica‐TiO₂ (CSMS@TiO₂‐GLYMO‐APB) for N‐glycopeptide enrichment from biological samples, involving trypsin digestion, enrichment, deglycosylation with PNGase F, and subsequent mass spectrometry (MALDI‐TOF MS and Nano‐LC‐MS/MS)
Mohamed Adly Gab‐Allah, Maryam Adelipour, Hyojin Hwang, Reham M. Marzouk, Heejin Lim, Jooyeon Oh, Ji‐Hyun Cha, Jaebeom Lee, Jeongkwon Kim   +8 more
wiley   +1 more source

Reconstitution of glycan-driven MHC I recycling reveals calreticulin as mediator between TAPBPR and tapasin

Heinke TJ, Fahim A, Popovic N, Rath T, Morgner N, Trowitzsch S, Tampé R.   +6 more
europepmc   +1 more source

High-throughput glycosylation screening method for biologics development using MALDI-TOF-MS. [PDF]

Commun Chem
Zhang W, Xie L, Zhao H, Ma X, Ren S.
europepmc   +1 more source

Nanopore Trap for Label‐Free Fingerprinting of Surface‐modified Single Nanoparticles

Small Methods, EarlyView.
A solid‐state nanopore trapping‐based methodology combines “trap‐release” measurement protocol with multiple features extracted from ionic current of trapping events to generate unique electrical fingerprints of nanoparticles with distinct surface functional layers.
Nianduo Cai, Tzu‐Heng Chen, Yunfei Teng, Akhil Sai Naidu, Aleksandra Radenovic   +4 more
wiley   +1 more source

Stapling of β-Glucans Increases Antibody Binding. [PDF]

J Am Chem Soc
Ledvinka J, Kullmann R, Reuber EE, Weikl T, Ricardo MG, Seeberger PH.   +5 more
europepmc   +1 more source

Maltase 1 regulates DENV2 infection and life history in Aedes aegypti

Insect Science, EarlyView.
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li, Jin Cheng, Ya‐Ming Zou, Quan‐Chao Liu, Ding Zhu, Ce‐Jie Lan   +5 more
wiley   +1 more source