Results 31 to 40 of about 172,036 (354)
The role of the mobile proton in fucose migration [PDF]
, 2019 Fucose migration reactions represent a substantial challenge in the analysis of fucosylated glycan structures by mass spectrometry. In addition to the well-established observation of transposed fucose residues in glycan-dissociation product ions, recent ...
Helden, Gert von +7 more
core +1 more source
Biosynthetic Glycan Labeling [PDF]
Journal of the American Chemical Society, 2021 ABSTRACTGlycans are ubiquitous and play important biological roles, yet chemical methods for probing their structure and function within cells remain limited. Strategies for studying other biomacromolecules, such as proteins, often exploit chemoselective reactions for covalent modification, capture, or imaging.
Victoria M. Marando +5 more
openaire +3 more sources
Frontiers in Bioengineering and Biotechnology, 2020 Peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidases (PNGases, N-glycanases, EC 3.5.1.52) are indispensable tools in releasing N-glycans from glycoproteins.
Rui-Rui Guo +9 more
doaj +1 more source
A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen. [PDF]
, 2018 Anti-carbohydrate monoclonal antibodies (mAbs) hold great promise as cancer therapeutics and diagnostics. However, their specificity can be mixed, and detailed characterization is problematic, because antibody-glycan complexes are challenging to ...
Amon, Ron +12 more
core +2 more sources
Carrier-Free Immobilization of Rutin Degrading Enzyme Extracted From Fusarium spp.
Frontiers in Bioengineering and Biotechnology, 2020 In this study, a strain with rutin degrading enzyme (RDE) activity was screened from moldy tartary buckwheat and subsequently identified as Fusarium spp. The structure and enzyme characteristics of CLEA-RDE formed by immobilization via cross-linking were
Yuan-Yuan Zang +4 more
doaj +1 more source
From structural to functional glycomics: core substitutions as molecular switches for shape and lectin affinity of N-glycans [PDF]
, 2009 Glycan epitopes of cellular glycoconjugates act as versatile biochemical signals (sugar coding). Here, we test the hypothesis that the common N-glycan modifications by core fucosylation and introduction of the bisecting N-acetylglucosamine moiety have ...
André, Sabine +4 more
core +1 more source
Probing Virus–Glycan Interactions Using Glycan Microarrays [PDF]
, 2011 Glycan microarrays are surfaces that contain immobilized oligosaccharides or glycoconjugates and have proven useful in probing the interactions between glycan-binding proteins (GBPs) and individual glycans. Such glycan microarrays have been especially important in studying virus-glycan interactions, as most viruses express one or more GBPs important ...
Jamie, Heimburg-Molinaro +6 more
openaire +2 more sources
Glycomic analysis of high density lipoprotein shows a highly sialylated particle. [PDF]
, 2014 Many of the functional proteins and lipids in high density lipoprotein (HDL) particles are potentially glycosylated, yet very little is known about the glycoconjugates of HDL.
German, J Bruce +6 more
core +1 more source
Biology, 2023 The giant African snail (Order Stylommatophora: Family Achatinidae), Achatina fulica (Bowdich, 1822), is the most significant and invasive land snail pest.
Pornpavee Nualnisachol +2 more
doaj +1 more source
Synthesis and glycosidation of building blocks of D-altrosamine
Frontiers in Chemistry, 2022 Presented herein is a streamlined synthesis of building blocks of a rare sugar D-altrosamine. Also investigated was the glycosylation of different glycosyl acceptors with differentially protected altrosamine donors.
Mariya Novakova +4 more
doaj +1 more source