Results 51 to 60 of about 144,829 (355)
Immunization expands HIV-1 V3-glycan specific B-cells in mice and macaques
Nature, 2019 Broadly neutralizing monoclonal antibodies protect against infection with HIV-1 in animal models, suggesting that a vaccine that elicits these antibodies would be protective in humans.
A. Escolano +31 more
semanticscholar +1 more source
The international glycan repository GlyTouCan version 3.0
Nucleic Acids Res., 2020 Glycans serve important roles in signaling events and cell-cell communication, and they are recognized by lectins, viruses and bacteria, playing a variety of roles in many biological processes.
Akihiro Fujita +8 more
semanticscholar +1 more source
FoodsWhole grain foods have been recommended to preserve biologically active components and benefit human health. The effect of the addition amount of whole sweet potato flour (WSPF, 25%, 51%, and 75%) on the physicochemical and structural properties of ...
Yan Zeng +4 more
doaj +1 more source
Molecules, 2022 Glycan-based electrochemical biosensors are emerging as analytical tools for determining multiple molecular targets relevant to diagnosing infectious diseases and detecting cancer biomarkers. These biosensors allow for the detection of target analytes at
Danilo Echeverri, Jahir Orozco
doaj +1 more source
Automated Glycan Assembly: A Perspective
Journal of the American Chemical Society, 2019 The intrinsic complexity of carbohydrate structures has hampered access to pure glycans and hence impeded progress in the glycosciences. Automated Glycan Assembly (AGA) has facilitated the procurement of synthetic glycans, to be used in diagnostics ...
Mónica Guberman, P. Seeberger
semanticscholar +1 more source
Metastases: the glycan connection [PDF]
Breast Cancer Research, 2000 An association between protein glycosylation and tumorigenesis has been recognized for over 10 years. Associations linking the importance of glycosylation events to tumor biology, especially the progression to metastatic disease, have been noted over many years, Recently, a mouse model in which beta1,6-N-acetylglucosaminyltransferase V (a rate-limiting
Couldrey, Christine, E Green, Jeffrey
openaire +2 more sources
Differential impact of glycoprotein glycosylation on Akkermansia muciniphila growth dynamics
Food Materials ResearchAkkermansia muciniphila, a pivotal symbiotic bacterium resident in the human gut mucosal layer, significantly influences the intricate balance between health and disease states.
Jia-Xin Zhang +3 more
doaj +1 more source
Glycoengineering of Therapeutic Antibodies with Small Molecule Inhibitors
Antibodies, 2021 Monoclonal antibodies (mAbs) are one of the cornerstones of modern medicine, across an increasing range of therapeutic areas. All therapeutic mAbs are glycoproteins, i.e., their polypeptide chain is decorated with glycans, oligosaccharides of ...
Shasha Li +5 more
doaj +1 more source
Impact of host cell line choice on glycan profile
Critical Reviews in Biotechnology, 2018 Protein glycosylation is post-translational modification (PTM) which is important for pharmacokinetics and immunogenicity of recombinant glycoprotein therapeutics.
Justin Goh, S. Ng
semanticscholar +1 more source
Biocatalytic β-glucosylation/β-galactosylation of Rebaudioside C by glycosynthases
Food Materials ResearchExtracts of Stevia rebaudiana Bertoni plant leaves contain a mixture of diterpene glycosides which possess high sweetness and are used as non-caloric sweeteners in foods and beverages.
Ye-Yang Yu +7 more
doaj +1 more source