Differential impact of glycoprotein glycosylation on Akkermansia muciniphila growth dynamics
Food Materials ResearchAkkermansia muciniphila, a pivotal symbiotic bacterium resident in the human gut mucosal layer, significantly influences the intricate balance between health and disease states.
Jia-Xin Zhang +3 more
doaj +1 more source
Glycosylated proteins preserved over millennia: N-glycan analysis of Tyrolean Iceman, Scythian Princess and Warrior. [PDF]
, 2014 An improved understanding of glycosylation will provide new insights into many biological processes. In the analysis of oligosaccharides from biological samples, a strict regime is typically followed to ensure sample integrity.
An, Hyun Joo +11 more
core +1 more source
Parvovirus glycan interactions [PDF]
Current Opinion in Virology, 2014 Members of the Parvoviridae utilize glycan receptors for cellular attachment and subsequent interactions determine transduction efficiency or pathogenic outcome. This review focuses on the identity of the glycan receptors utilized, their capsid binding footprints, and a discussion of the overlap of these sites with tropism, transduction, and ...
Lin-Ya, Huang +2 more
openaire +2 more sources
Glycan–protein interactions determine kinetics of N -glycan remodeling [PDF]
RSC Chemical Biology, 2020 Atomistic glycoprotein simulations reveal a site-specific availability of glycan substrates in time-resolved mass spectrometry of maturating enzyme kinetics.
Mathew, Corina +7 more
openaire +4 more sources
Biocatalytic β-glucosylation/β-galactosylation of Rebaudioside C by glycosynthases
Food Materials ResearchExtracts of Stevia rebaudiana Bertoni plant leaves contain a mixture of diterpene glycosides which possess high sweetness and are used as non-caloric sweeteners in foods and beverages.
Ye-Yang Yu +7 more
doaj +1 more source
Advanced Science, 2020 There is a pressing need to develop ways to deliver therapeutic macromolecules to their intracellular targets. Certain viral and bacterial proteins are readily internalized in functional form through lipid raft‐mediated/caveolar endocytosis, but ...
Norbert Imre +11 more
doaj +1 more source
Charge Characteristics of Agouti-Related Protein Implicate Potent Involvement of Heparan Sulfate Proteoglycans in Metabolic Function. [PDF]
, 2019 The endogenous melanocortin peptide agouti-related protein (AgRP) plays a well-known role in foraging, but its contribution to metabolic regulation is less understood.
Chen, Jihuan +9 more
core +1 more source
Expression and in vitro glycosylation of recombinant edible bird nest (EBN) mucin
Food Materials ResearchEdible bird's nest (EBN) is considered a delicacy in Chinese cuisine. The nests are produced by male swiftlets (Aerodramus sp.). Due to their high price, the nutritional benefit from EBN can currently only be afforded by affluent consumers.
Ge Cheng +4 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Structure analysis of biologically important prokaryotic glycopolymers [PDF]
, 2013 Of the many post-translational modifications organisms can undertake, glycosylation is the most prevalent and the most diverse. The research in this thesis focuses on the structural characterisation of glycosylation in two classes of glycopolymer (
Ventura, Valeria Victoria +1 more
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