Results 81 to 90 of about 181,761 (403)
Automated Glycan Assembly: A Perspective
Journal of the American Chemical Society, 2019 The intrinsic complexity of carbohydrate structures has hampered access to pure glycans and hence impeded progress in the glycosciences. Automated Glycan Assembly (AGA) has facilitated the procurement of synthetic glycans, to be used in diagnostics ...
Mónica Guberman, P. Seeberger
semanticscholar +1 more source
Structural analysis of the GPI glycan
PLOS ONE, 2021 Glycosylphosphatidylinositol (GPI) anchoring of proteins is an essential post-translational modification in all eukaryotes that occurs at the endoplasmic reticulum (ER) and serves to deliver GPI-anchored proteins (GPI-APs) to the cell surface where they play a wide variety of vital physiological roles.
Miyako Nakano +9 more
openaire +9 more sources
Biocatalytic β-glucosylation/β-galactosylation of Rebaudioside C by glycosynthases
Food Materials ResearchExtracts of Stevia rebaudiana Bertoni plant leaves contain a mixture of diterpene glycosides which possess high sweetness and are used as non-caloric sweeteners in foods and beverages.
Ye-Yang Yu +7 more
doaj +1 more source
Functioning of the dimeric GABA(B) receptor extracellular domain revealed by glycan wedge scanning [PDF]
The EMBO Journal 27, 9 (2008) 1321-1332, 2008 The G-protein-coupled receptor (GPCR) activated by the neurotransmitter GABA is made up of two subunits, GABA(B1) and GABA(B2). GABA(B1) binds agonists, whereas GABA(B2) is required for trafficking GABA(B1) to the cell surface, increasing agonist affinity to GABA(B1), and activating associated G proteins.
arxiv +1 more source
Bioinformatics Approach for Functional Glycomics [PDF]
, 2007 Presentation in the Human Glycomics Proteomics Disease Initiative (HGPI ...
James C. Paulson
core +2 more sources
Nature Structural &Molecular Biology, 2016 The threat of a major coronavirus pandemic urges the development of strategies to combat these pathogens. Human coronavirus NL63 (HCoV-NL63) is an α-coronavirus that can cause severe lower-respiratory-tract infections requiring hospitalization. We report
A. Walls +8 more
semanticscholar +1 more source
The Analyst, 2020 Retention time normalization of permethylated glycans and glycan isomers across different instruments and laboratories, using standard dextrin ladder. (Figure created with BioRender.com).
Sakshi Gautam +7 more
openaire +4 more sources
Animal Research and One Health, EarlyView., 2023 In the present study, we created the weight gain models with Min and Yorkshire pigs and conducted the metagenomics and metabolomics of colon contents and transcriptomics of colon tissue. Further, we revealed the characteristics and functions of the colonic microbiota in Min and Yorkshire pigs and analyzed their interactions with the host. Overall, this
Xiaoyu Huang +6 more
wiley +1 more source
Differential impact of glycoprotein glycosylation on Akkermansia muciniphila growth dynamics
Food Materials ResearchAkkermansia muciniphila, a pivotal symbiotic bacterium resident in the human gut mucosal layer, significantly influences the intricate balance between health and disease states.
Jia-Xin Zhang +3 more
doaj +1 more source
Molecular Therapy: Methods & Clinical Development, 2017 Atomic structures of adeno-associated virus (AAV)-DJ, alone and in complex with fondaparinux, have been determined by cryoelectron microscopy at 3 Å resolution. The gene therapy vector, AAV-DJ, is a hybrid of natural serotypes that was previously derived
Qing Xie +9 more
doaj +1 more source