Results 91 to 100 of about 88,542 (309)

Simple Routes to Stable Isotope-Coded Native Glycans

, 2023
Understanding the biological role of protein-linked glycans requires the reliable identification of glycans. Isomer separation and characterization often entail mass spectrometric detection preceded by high-performance chromatography on porous graphitic ...
Friedrich Altmann (33138), Johannes Helm (11632404), Martin Pabst (1274265), Clemens Grünwald-Gruber (11632407), Jonathan Urteil (11632413)   +4 more
core   +1 more source

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

Advanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer, Rong Zhu, Manuel Reithofer, Gerhard Stadlmayr, Katharina Stadlbauer, Panchika Prangkio, Christoph Rippel, Markus Hahn, Aniko Eva Kasztner, Stefanie Stohl, Petr Bednar, Daniel Ruzek, David Glück, Robert Tampé, Gordana Wozniak‐Knopp, Yoo Jin Oh, Miriam Klausberger, Peter Hinterdorfer   +17 more
wiley   +1 more source

Giardia spp.-induced microbiota dysbiosis disrupts intestinal mucin glycosylation

Gut Microbes
Infection with the protozoan parasite Giardia duodenalis (syn. intestinalis, lamblia) has been associated with intestinal mucus disruptions and microbiota dysbiosis. The mechanisms remain incompletely understood.
Elena Fekete, Thibault Allain, Olivia Sosnowski, Stephanie Anderson, Ian A. Lewis, Andre G. Buret   +5 more
doaj   +1 more source

Glycans

, 2019
Data source: Supporting information, https://doi.org/10.1002/pmic.201800482Epithelial ovarian cancer is one of the most fatal gynecological malignancies in adult women.
Oehler, MK, Briggs, M.T., Oehler, M.K., Packer, N.H., Briggs, MT, Mittal, P., Everest-Dass, AV, Mittal, P, Ho, Y.Y., Condina, MR, Packer, NH, Everest-Dass, A.V., Hoffmann, P, Hoffmann, P., Ho, YY, Kaur, G., Condina, M.R., Kaur, G, Martin K. Oehler, Matthew T. Briggs, Arun V. Everest‐Dass, Peter Hoffmann, Mark R. Condina, Gurjeet Kaur, Yin Ying Ho, Parul Mittal, Nicolle H. Packer   +26 more
core   +1 more source

Bio‐Inspired Oligocellulose‐Regulated Ice‐Water Interfaces Enable Sustained Ion Transport in Frozen Aqueous Zinc Batteries

Advanced Science, EarlyView.
Inspired by antifreeze glycoproteins (AFGPs), we synthesized a type of oligomeric cellulose (OC‐8) to inhibit ice formation and enlarge the inter‐ice water channel for transportation. Typical confocal fluorescence experiments display the expansion of the ice‐water interface for zinc‐ion transport.
Zeyu Zhu, Jingxuan Pan, Haoran Ma, Boya Yuan, Cristina Carucci, Sunghak Park, Chong Gao, Minmin Liang, Kaiqi Li, Wei Li, Dan Wang, Xiaoting Chen, Zhiyuan He   +12 more
wiley   +1 more source

Branched mannan and xyloglucan as a dynamic duo in plant cell walls

The Cell Surface, 2023
Annika Grieß-Osowski, Cătălin Voiniciuc   +1 more
doaj   +1 more source

glycans [PDF]

, 2014
Citation: 'glycans' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.G02645 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage
openaire   +1 more source

CHST1 Drives Immunotherapy Resistance in Triple‐Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF–CCL20–Macrophage Axis

Advanced Science, EarlyView.
Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang, Xiao‐Han Ying, Ruo‐Qing Wang, Qun Zhang, Li Chen, Zhi‐Ming Shao, Jun‐Jie Li   +6 more
wiley   +1 more source

Studies on the biosynthesis of ABH and Lewis epitopes on O-glycans

, 2006
ABH and Lewis antigens are carbohydrate epitopes (glycans) found on a wide variety of cell surfaces. They are involved in many biological processes, e.g transplantation rejection, bacterial and viral adhesion, cell-cell communication and metastasis.
Jonas Löfling (19493101)
core  

Expression profiles of representative GSL-glycans.

, 2015
(a) Gg-series glycans. (b) Gb-series glycnas. (c) MALDI-TOF/TOF MS spectra of GSL-glycans with a (Hex)5(HexNAc)2 composition. In theory, signature fragmentation peaks at m/z 934.9 and 975.4 are specifically generated from Gb- and (n)Lc-series GSL-glycans,
Masumi Tsuda (232735), Shinya Tanaka (148975), Jinhua Piao (763702), Yasuro Shinohara (317551), Taichi Kimura (148969), Kazue Okada (763701), Jun-ichi Furukawa (763700)   +6 more
core   +1 more source