Results 71 to 80 of about 88,542 (309)

Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures [PDF]

, 2002
The structure of N-linked glycans is determined by a complex, anabolic, intracellular pathway but the exact role of individual glycans is not always clear.
Gill, A C, Lilley, K, Ritchie, M A, Deery, M J   +3 more
core  

Metabolic Labeling of Bacterial Glycans

, 2021
International audienceAlthough their impact in biology and cellular communication are now well established, in situ visualization of glycans has long remained elusive due to the lack of suitable and general imaging techniques.
Boris Vauzeilles, Christophe Biot, Bourdreux, Yann, Vauzeilles, Boris, Guianvarc’h, Dominique, Dominique Guianvarc’h, Biot, Christophe, Yann Bourdreux   +7 more
core   +1 more source

Antibody‐Precomplexed Hemagglutinin Constructs Multivalently Bind Sialylated Glycan Receptors with Variable Valencies

Advanced Materials Interfaces, EarlyView.
Hemagglutinin precomplexation with antibodies (Abs) results in broad valency distributions, though it increases the total avidity from mM to nM to high nM. The valency distribution and the orientation of multivalent HA‐Ab complexes determine the extent of binding to different types of assays, whether the receptors are displayed in 2D or 3D.
Daniel Y. E. L. Tambuwun, María Ríos Carrasco, Elif Uslu, Geert‐Jan P. H. Boons, Nadia J. Mokiem, Albert J. R. Heck, Victor C. Yin, Robert P. de Vries, Jurriaan Huskens   +8 more
wiley   +1 more source

Effects of a polysaccharide-based multi-ingredient supplement on salivary immunity in non-elite marathon runners

Journal of the International Society of Sports Nutrition, 2019
Background Extreme exercise may alter the innate immune system. Glycans are involved in several biological processes including immune system regulation.
Emma Roca, Elisabet Cantó, Lexa Nescolarde, Lidia Perea, Antoni Bayes-Genis, Oriol Sibila, Silvia Vidal   +6 more
doaj   +1 more source

Silk Fibroin Nanofiber–Immobilized Horseradish Peroxidase Enables Continuous Preparation of Injectable Hydrogels With Negligible Residual Enzyme for Drug Delivery

Advanced Materials Technologies, EarlyView.
Overcoming the immunogenicity challenges of enzyme‐mediated crosslinking, a flow‐through reactor utilizing SFNF‐HRP enables the continuous production of injectable hydrogels. This continuous platform ensures homogeneous crosslinking while minimizing residual HRP in the resulting hydrogels.
Ayari Miyawaki, Shinji Sakai
wiley   +1 more source

Mass spectrometry of glycans [PDF]

Biochemistry (Moscow), 2013
Powerful new strategies based on mass spectrometry are revolutionizing the structural analysis and profiling of glycans and glycoconjugates. We survey here the major biosynthetic pathways that underlie the biological diversity in glycobiology, with emphasis on glycoproteins, and the approaches that can be used to address the resulting heterogeneity ...
Liang, Han, Catherine E, Costello
openaire   +2 more sources

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Deciphering disease through glycan codes: leveraging lectin microarrays for clinical insights

Acta Biochimica et Biophysica Sinica
Glycosylation, a crucial posttranslational modification, plays a significant role in numerous physiological and pathological processes. Lectin microarrays, which leverage the high specificity of lectins for sugar binding, are ideally suited for profiling
Yang Hangzhou, Lin Zihan, Wu Bo, Xu Jun, Tao Sheng-Ce, Zhou Shumin   +5 more
doaj   +1 more source

Pregnancy Galectinology: Insights Into a Complex Network of Glycan Binding Proteins

Frontiers in Immunology, 2019
Galectins are a phylogenetically conserved family of soluble β-galactoside binding proteins, consisting of 15 different types, each with a specific function.
Sandra M. Blois, Sandra M. Blois, Gabriela Dveksler, Gerardo R. Vasta, Nancy Freitag, Véronique Blanchard, Gabriela Barrientos   +6 more
doaj   +1 more source

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

Advanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier, Megane Grah Kple, Julen Ariztia, Marion Leroux, Mathieu Moreau, Michael Claron, Maxime Cheveau, Adam Laouafa, Agnieszka Kownacka, Camille Petitot, John Simonet, Alexandre M. M. Dias, Sophie Poty, Charles Truillet, Bertrand Collin, Alexandra Oudot, Franck Denat   +16 more
wiley   +1 more source