Results 51 to 60 of about 88,542 (309)

Determining the Importance of Carbohydrate-Based Structures in Murine Norovirus Binding to Commensal Bacteria

Viruses
Norovirus–bacterial interactions influence viral replication and immune responses, yet the molecular details that mediate binding of these viruses to commensal bacteria are unknown.
Jasmine L. Madrigal, Joseph P. Sullivan, Feba Mathew, Melanie Bland, Melissa K. Jones   +4 more
doaj   +1 more source

Heterogeneity of glycan biomarker clusters as an indicator of recurrence in pancreatic cancer

Frontiers in Oncology, 2023
IntroductionOutcomes following tumor resection vary dramatically among patients with pancreatic ductal adenocarcinoma (PDAC). A challenge in defining predictive biomarkers is to discern within the complex tumor tissue the specific subpopulations and ...
Luke Wisniewski, Samuel Braak, Zachary Klamer, ChongFeng Gao, Chanjuan Shi, Peter Allen, Brian B. Haab   +6 more
doaj   +1 more source

Comparative analysis of N-glycans in the ungerminated and germinated stages of Oryza sativa

, 2015
All fundamental information such as signal transduction, metabolic control, infection, cell-to-cell signaling, and cell differentiation related to the growth of plants are preserved in germs.
Miyanishi, Nobumitsu, Hirotsu, Naoki, Horiuchi, Risa   +2 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Evaluating the Pathogenic Potential of IgE Targeting Cross-Reactive Carbohydrate Determinants in Dogs

Animals
Cross-reactive carbohydrate determinants (CCDs) are complex N-glycans shared among allergens of plant, insect venom, and nematode origin. In allergic humans, IgE anti-CCD often develop and cause discrepancies between serological and skin tests.
Thierry Olivry, Ana Mas Fontao, Laura Widorn, Ralf S. Mueller   +3 more
doaj   +1 more source

Synthesis and Antibody Binding Studies of Schistosome-Derived Oligo-α-(1-2)-l-Fucosides

Molecules, 2021
Schistosomiasis is caused by blood-dwelling parasitic trematodes of the genus Schistosoma and is classified by the WHO as the second most socioeconomically devastating parasitic disease, second only to malaria.
Michael R. Harvey, Fabrizio Chiodo, Wouter Noest, Cornelis H. Hokke, Gijsbert A. van der Marel, Jeroen D.C. Codée   +5 more
doaj   +1 more source

Updates to the Symbol Nomenclature for Glycans guidelines

, 2019
The Symbol Nomenclature for Glycans (SNFG) is a community-curated standard for the depiction of monosaccharides and complex glycans using various colored-coded, geometric shapes, along with defined text additions.
Lisacek, Frederique, Woods, Robert, Narimatsu, Hisashi, Mazumder, Raja, Henrissat, Bernard, Toukach, Philip, O'Boyle, Noel, Prestegard, James, Kornfeld, Stuart, Neelamegham, Sriram, Varki, Ajit, Seeberger, Peter, Frank, Martin, Kanehisa, Minoru, Aoki-Kinoshita, Kiyoko, York, William, Vliegenthart, J, Aebi, Markus, Paulson, James, Dell, Anne, Freeze, Hudson, Cummings, Richard, Hart, Gerald, Perez, Serge, Etzler, Marilynn, Kinoshita, Taroh, O’boyle, Noel, Ranzinger, Rene, Bertozzi, Carolyn, Darvill, Alan, Edwards, Nathan, Lütteke, Thomas, Yamada, Issaku, Marth, Jamey, Rudd, Pauline, Packer, Nicolle, Stanley, Pamela, Bolton, Evan, Schnaar, Ronald, Knirel, Yuriy, Taniguchi, Naoyuki, Toukach P, Frank M, Luetteke, Thomas, Lisacek F, Woods RJ, Packer, Nicolle H., Aoki-Kinoshita K, Packer, Nicolle H, Woods, Robert J., Bolton E, Lütteke T, Neelamegham S, et al., Woods, Robert J, Varki A, O'Boyle N, Packer NH, Stanley P, The SNFG Discussion Group   +59 more
core   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

FUT8 Is a Critical Driver of Prostate Tumour Growth and Can Be Targeted Using Fucosylation Inhibitors

Cancer Medicine
Background An unmet clinical need requires the discovery of new treatments for men facing advanced prostate cancer. Aberrant glycosylation is a universal feature of cancer cells and plays a key role in tumour growth, immune evasion and metastasis ...
Kayla Bastian, Margarita Orozco‐Moreno, Huw Thomas, Kirsty Hodgson, Eline A. Visser, Emiel Rossing, Johan F. A. Pijnenborg, Nienke Eerden, Laura Wilson, Hasvini Saravannan, Oliver Hanley, Grace Grimsley, Fiona Frame, Ziqian Peng, Bridget Knight, Paul McCullagh, John McGrath, Malcolm Crundwell, Lorna Harries, Norman J. Maitland, Rakesh Heer, Ning Wang, Ethan D. Goddard‐Borger, Ramon Hurtado Guerrero, Thomas J. Boltje, Richard R. Drake, Emma Scott, David J. Elliott, Jennifer Munkley   +28 more
doaj   +1 more source

The forecasting power of the mucin-microbiome interplay in livestock respiratory diseases

Veterinary Quarterly
Complex respiratory diseases are a significant challenge for the livestock industry worldwide. These diseases considerably impact animal health and welfare and cause severe economic losses.
Núria Mach
doaj   +1 more source