Results 41 to 50 of about 86,469 (209)
Glycan Microarrays as Chemical Tools for Identifying Glycan Recognition by Immune Proteins
Frontiers in Chemistry, 2019 Glycans and glycan binding proteins (GBPs or lectins) are essential components in almost every aspect of immunology. Investigations of the interactions between glycans and GBPs have greatly advanced our understanding of the molecular basis of these ...
Chao Gao +5 more
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Targeting cell surface glycans with lectin-coated fluorescent nanodiamonds
, 2022 Glycosylation is arguably the most important functional post-translational modification in brain cells and abnormal cell surface glycan expression has been associated with neurological diseases and brain cancers. In this study we developed a novel method
Fard, Mina Ghanimi +24 more
core +1 more source
The Analyst, 2020 Retention time normalization of permethylated glycans and glycan isomers across different instruments and laboratories, using standard dextrin ladder. (Figure created with BioRender.com).
Sakshi Gautam +7 more
openaire +3 more sources
Resolving the TorsinA Oligomerization Conundrum: The Glycan Hypothesis
Frontiers in Molecular Biosciences, 2020 TorsinA is a AAA+ ATPase involved in the severe neurological disease Early Onset Torsion Dystonia. Despite the impressive progress in the field in the recent years, the structural organization and function of this intriguing molecule is still not clear ...
Christian Fercher, Lucía F. Zacchi
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Sialylated and sulfated N-Glycans in MDCK and engineered MDCK cells for influenza virus studies
Scientific Reports, 2022 The Madin-Darby canine kidney (MDCK) cell line is an in vitro model for influenza A virus (IAV) infection and propagation. MDCK-SIAT1 (SIAT1) and humanized MDCK (hCK) cell lines are engineered MDCK cells that express N-glycans with elevated levels of ...
Lauren Byrd-Leotis +6 more
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Pathogens, 2021 Parasitic helminths are master manipulators of host immunity. Their strategy is complex and involves the release of excreted/secreted products, including extracellular vesicles (EVs). The protein and miRNA contents of EVs have been characterised for many
Maude Dagenais +7 more
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Frontiers in Molecular BiosciencesIntroductionCurdlan is a linear homopolysaccharide composed of β-1→3-linked glucose units. It is extracted from some bacteria as an exopolysaccharide and employed in the food industry due to its remarkable rheological and thermal behaviors.
Fabiana Esposito +5 more
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Myeloid C-Type Lectin Receptors in Viral Recognition and Antiviral Immunity
Viruses, 2017 Recognition of viral glycans by pattern recognition receptors (PRRs) in innate immunity contributes to antiviral immune responses. C-type lectin receptors (CLRs) are PRRs capable of sensing glycans present in viral pathogens to activate antiviral immune ...
João T. Monteiro, Bernd Lepenies
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The Roles of Glycans in Bladder Cancer
Frontiers in Oncology, 2020 Bladder cancer is one of the most common malignant tumors of the urogenital system with high morbidity and mortality worldwide. Early diagnosis and personalized treatment are the keys to successful bladder cancer treatment.
Yuli Jian +6 more
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Heterogeneity of glycan biomarker clusters as an indicator of recurrence in pancreatic cancer
Frontiers in Oncology, 2023 IntroductionOutcomes following tumor resection vary dramatically among patients with pancreatic ductal adenocarcinoma (PDAC). A challenge in defining predictive biomarkers is to discern within the complex tumor tissue the specific subpopulations and ...
Luke Wisniewski +6 more
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