Results 41 to 50 of about 116,660 (304)
How do nematodes transfer phosphorylcholine to carbohydrates? [PDF]
, 2010 An unusual aspect of the biology of nematodes is the attachment of phosphorylcholine (PC) to carbohydrate. The attachment appears to play an important role in nematode development and, in some parasitic species, in immunomodulation.
Harnett, W., Houston, K.M., Rzepecka, J.
core +1 more source
Finite Dimension: A Mathematical Tool to Analise Glycans [PDF]
, 2018 There is a need to develop widely applicable tools to understand glycan organization, diversity and structure. We present a graph-theoretical study of a large sample of glycans in terms of finite dimension, a new metric which is an adaptation to finite ...
Alonso, Juan Manuel +4 more
core +2 more sources
From structural to functional glycomics: core substitutions as molecular switches for shape and lectin affinity of N-glycans [PDF]
, 2009 Glycan epitopes of cellular glycoconjugates act as versatile biochemical signals (sugar coding). Here, we test the hypothesis that the common N-glycan modifications by core fucosylation and introduction of the bisecting N-acetylglucosamine moiety have ...
André, Sabine +4 more
core +1 more source
Parvovirus glycan interactions [PDF]
Current Opinion in Virology, 2014 Members of the Parvoviridae utilize glycan receptors for cellular attachment and subsequent interactions determine transduction efficiency or pathogenic outcome. This review focuses on the identity of the glycan receptors utilized, their capsid binding footprints, and a discussion of the overlap of these sites with tropism, transduction, and ...
Lin-Ya, Huang +2 more
openaire +2 more sources
Glycan–protein interactions determine kinetics of N -glycan remodeling [PDF]
RSC Chemical Biology, 2020 Atomistic glycoprotein simulations reveal a site-specific availability of glycan substrates in time-resolved mass spectrometry of maturating enzyme kinetics.
Mathew, Corina +7 more
openaire +4 more sources
Glycan Microarrays as Chemical Tools for Identifying Glycan Recognition by Immune Proteins
Frontiers in Chemistry, 2019 Glycans and glycan binding proteins (GBPs or lectins) are essential components in almost every aspect of immunology. Investigations of the interactions between glycans and GBPs have greatly advanced our understanding of the molecular basis of these ...
Chao Gao +5 more
doaj +1 more source
Resolving the TorsinA Oligomerization Conundrum: The Glycan Hypothesis
Frontiers in Molecular Biosciences, 2020 TorsinA is a AAA+ ATPase involved in the severe neurological disease Early Onset Torsion Dystonia. Despite the impressive progress in the field in the recent years, the structural organization and function of this intriguing molecule is still not clear ...
Christian Fercher, Lucía F. Zacchi
doaj +1 more source
Structure analysis of biologically important prokaryotic glycopolymers [PDF]
, 2013 Of the many post-translational modifications organisms can undertake, glycosylation is the most prevalent and the most diverse. The research in this thesis focuses on the structural characterisation of glycosylation in two classes of glycopolymer (
Ventura, Valeria Victoria +1 more
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Myeloid C-Type Lectin Receptors in Viral Recognition and Antiviral Immunity
Viruses, 2017 Recognition of viral glycans by pattern recognition receptors (PRRs) in innate immunity contributes to antiviral immune responses. C-type lectin receptors (CLRs) are PRRs capable of sensing glycans present in viral pathogens to activate antiviral immune ...
João T. Monteiro, Bernd Lepenies
doaj +1 more source
The Roles of Glycans in Bladder Cancer
Frontiers in Oncology, 2020 Bladder cancer is one of the most common malignant tumors of the urogenital system with high morbidity and mortality worldwide. Early diagnosis and personalized treatment are the keys to successful bladder cancer treatment.
Yuli Jian +6 more
doaj +1 more source