Results 61 to 70 of about 86,469 (209)

Monosaccharide coatings on nanoparticles affect protein corona formation but not the interaction with their binding receptor

Frontiers in Nanotechnology
Surface coatings with polyethylene glycol (PEG) polymers have often been employed to improve nanoparticles (NPs) biocompatibility and extend circulation time by reducing protein adsorption.
Eva Clemente, Ruth Mateu, Avelino Ferreira, Tanja Ludtke, Tanja Ludtke, Hender Lopez, Sergio E. Moya, Luigi Lay, Mahmoud G. Soliman, Marco P. Monopoli   +9 more
doaj   +1 more source

N-glycans of human amniotic fluid transferrin stimulate progesterone production in human first trimester trophoblast cells in vitro [PDF]

, 2004
Aims: During pregnancy, the placenta produces a variety of steroid hormones and proteins. Several of these substances have been shown to exert immunomodulatory effects.
Briese, V., Friese, K., Richter, D.-U., Gundel, G., Mylonas, I., Unverzagt, C., Jeschke, U., Müller, H., Streu, A.   +8 more
core   +1 more source

Significant Associations of IgG Glycan Structures With Chronic Graft-Versus-Host Disease Manifestations: Results of the Cross-Sectional NIH Cohort Study

Frontiers in Immunology, 2021
Chronic graft-versus-host disease (cGvHD) is a systemic alloimmune and autoimmune disorder and a major late complication of allogeneic hematopoietic stem cell transplantation (alloHSCT).
Ema Prenc, Ema Prenc, Drazen Pulanic, Drazen Pulanic, Maja Pucic-Bakovic, Ivo Ugrina, Ivo Ugrina, Lana Desnica, Milan Milosevic, Milan Milosevic, Filip Pirsl, Sandra Mitchell, Jeremy Rose, Radovan Vrhovac, Radovan Vrhovac, Damir Nemet, Damir Nemet, Gordan Lauc, Steven Z. Pavletic   +18 more
doaj   +1 more source

Probing Virus–Glycan Interactions Using Glycan Microarrays [PDF]

, 2011
Glycan microarrays are surfaces that contain immobilized oligosaccharides or glycoconjugates and have proven useful in probing the interactions between glycan-binding proteins (GBPs) and individual glycans. Such glycan microarrays have been especially important in studying virus-glycan interactions, as most viruses express one or more GBPs important ...
Jamie, Heimburg-Molinaro, Mary, Tappert, Xuezheng, Song, Yi, Lasanajak, Gillian, Air, David F, Smith, Richard D, Cummings   +6 more
openaire   +2 more sources

Characterization and downstream mannose phosphorylation of human recombinant α-L-iduronidase produced in Arabidopsis complex glycan-deficient (cgl) seeds [PDF]

, 2013
This work was supported by a Wellcome Trust award to TMG.Mucopolysaccharidosis (MPS) I is a lysosomal storage disease caused by a deficiency of α-L-iduronidase (IDUA) (EC 3.2.1.76); enzyme replacement therapy is the conventional treatment for this ...
Brooks, Doug, Gloster, Tracey M., Vocadlo, D.J., Brooks, D., Kolarich, Daniel, Kermode, Allison R, Kermode, Allison R., Haselhorst, T., Qian, Y., Gloster, Tracey M, Qian, Yi, Gloster, Tracey, Kolarich, D., Haselhorst, Thomas, Packer, N.H., Pierce, Owen, He, X., von Itzstein, Mark, Gloster, T.M., Packer, Nicolle H., He, Xu, Pierce, O., Packer, Nicolle H, Vocadlo, David J, von Itzstein, M., Kermode, A.R., Vocadlo, David J.   +26 more
core   +1 more source

Structural feature of N-glycans of bamboo shoot glycoproteins: useful source of plant antigenic N-glycans [PDF]

, 2017
An effective method to prepare plant complex type (PCT) N-glycans in large amounts has been required to evaluate their immunological activity. In this study, we found that glycoproteins in bamboo shoots predominantly carry PCT N-glycans including the ...
Megumi, Maeda, Yoshinobu, Kimura, Kaori, Furuta, Tanabe, Chinatsu   +3 more
core   +2 more sources

Effects of a polysaccharide-based multi-ingredient supplement on salivary immunity in non-elite marathon runners

Journal of the International Society of Sports Nutrition, 2019
Background Extreme exercise may alter the innate immune system. Glycans are involved in several biological processes including immune system regulation.
Emma Roca, Elisabet Cantó, Lexa Nescolarde, Lidia Perea, Antoni Bayes-Genis, Oriol Sibila, Silvia Vidal   +6 more
doaj   +1 more source

Mass spectrometry of glycans [PDF]

Biochemistry (Moscow), 2013
Powerful new strategies based on mass spectrometry are revolutionizing the structural analysis and profiling of glycans and glycoconjugates. We survey here the major biosynthetic pathways that underlie the biological diversity in glycobiology, with emphasis on glycoproteins, and the approaches that can be used to address the resulting heterogeneity ...
Liang, Han, Catherine E, Costello
openaire   +2 more sources

Deciphering disease through glycan codes: leveraging lectin microarrays for clinical insights

Acta Biochimica et Biophysica Sinica
Glycosylation, a crucial posttranslational modification, plays a significant role in numerous physiological and pathological processes. Lectin microarrays, which leverage the high specificity of lectins for sugar binding, are ideally suited for profiling
Yang Hangzhou, Lin Zihan, Wu Bo, Xu Jun, Tao Sheng-Ce, Zhou Shumin   +5 more
doaj   +1 more source

Pregnancy Galectinology: Insights Into a Complex Network of Glycan Binding Proteins

Frontiers in Immunology, 2019
Galectins are a phylogenetically conserved family of soluble β-galactoside binding proteins, consisting of 15 different types, each with a specific function.
Sandra M. Blois, Sandra M. Blois, Gabriela Dveksler, Gerardo R. Vasta, Nancy Freitag, Véronique Blanchard, Gabriela Barrientos   +6 more
doaj   +1 more source