Results 31 to 40 of about 86,469 (209)

Genomic and Biochemical Analysis of N Glycosylation in the Mushroom-Forming Basidiomycete Schizophyllum commune [PDF]

, 2009
N-linked glycans of Schizophyllum commune consist of Man(5-9)GlcNAc(2) structures. Lack of further glycan maturation is explained by the absence of genes encoding such functions in this and other homobasidiomycetes.
de Jong, J.F., Jong, J.F., de, Wosten, H.A.B., Ohm, R.A., Bosch, G.B.M., van den, Molecular Microbiology, Lugones, L.G., Sub Molecular Microbiology, van den Bosch, G.B.M., Sub Membrane Biochemistry & Biophysics, Rouwendal, G.J.A., Bosch, D., Dep Scheikunde, Berends, E., Membrane Enzymology   +14 more
core   +2 more sources

Identification and functional characterization of a highly divergent N-acetylglucosaminyltransferase I (TbGnTI) in Trypanosoma brucei [PDF]

, 2014
Trypanosoma brucei expresses a diverse repertoire of N-glycans, ranging from oligomannose and paucimannose structures to exceptionally large complex N-glycans.
Damerow, Manuela, Ferguson, Michael A. J.; id_orcid, Güther, M. Lucia S., Wu, Di, Mehlert, Angela, Rodrigues, Joao A.   +5 more
core   +1 more source

Glycan signatures for the identification of cisplatin‐resistant testicular cancer cell lines: Specific glycoprofiling of human chorionic gonadotropin (hCG)

Cancer Medicine, 2022
Background Testicular cancer (TC) is the most frequent type of cancer among young men aged between 15 and 34 years. TC is treated using cisplatin, but 3%–5% of TC patients fail to respond to cisplatin, with a very bad to fatal prognosis.
Michal Hires, Eduard Jane, Katarina Kalavska, Michal Chovanec, Michal Mego, Peter Kasak, Tomas Bertok, Jan Tkac   +7 more
doaj   +1 more source

Fluorescent Glycan Derivatives: Their Use for Natural Glycan Microarrays [PDF]

ACS Chemical Biology, 2009
Glycan microarrays have become powerful tools in the investigation of biological systems because they enable fast, quantitative, and simultaneous analysis of glycan-protein interactions with small quantities of samples. One hurdle in the construction of glycan microarrays is to obtain a diverse set of glycans for immobilization on surfaces.
Sungjin, Park, Jung-Won, Sung, Injae, Shin   +2 more
openaire   +2 more sources

Uukuniemi Phlebovirus assembly and secretion leave a functional imprint on the Virion Glycome [PDF]

, 2014
Uukuniemi virus (UUKV) is a model system for investigating the genus Phlebovirus of the Bunyaviridae. We report the UUKV glycome, revealing differential processing of the Gn and Gc virion glycoproteins.
Scrivens, JH, Crispin, Max, Huiskonen, JT, Scrivens, James H., Bitto, David, Crispin, Matthew, Harvey, David J, Bitto, D, Scrivens, James, Huiskonen, Juha T, Bowden, Thomas A, Crispin, M, Bowden, Thomas A., Scrivens, James H, Edgeworth, Matthew, Halldorsson, Steinar, Huiskonen, Juha T., Bonomelli, Camille, Edgeworth, M, Bowden, TA, Bonomelli, C, Harvey, David J., Harvey, DJ, Halldorsson, S   +23 more
core   +1 more source

‐glycans

, 2023
Sulfated N- and O-glycans exist in trace levels which are challenging to detect, especially when abundant neutral and sialylated glycans are present.
Hinou, Hiroshi, Hiroshi Hinou, Montalban, Bryan M., Bryan M. Montalban   +3 more
core   +1 more source

Investigating virus–glycan interactions using glycan microarrays [PDF]

Current Opinion in Virology, 2014
While all viruses must transit the plasma membrane of mammalian cells to initiate infection, we know little about the complex processes involved in viral attachment, which commonly involve recognition of glycans by viral proteins. Glycan microarrays derived from both synthetic glycans and natural glycans isolated through shotgun glycomics approaches ...
David F, Smith, Richard D, Cummings
openaire   +2 more sources

The exploitation of human glycans by Group A Streptococcus

, 2022
Host carbohydrates, or glycans, have been implicated in the pathogenesis of many bacterial infections. Group A Streptococcus (GAS) is a Gram-positive bacterium that readily colonises the skin and oropharynx, and is a significant cause of mortality in ...
Sanderson-Smith, Martina, Indraratna, Anuk D, Skropeta, Danielle, Everest-Dass, Arun   +3 more
core   +1 more source

‐Glycans by Conformer Distribution Fingerprinting using Ion Mobility Mass Spectrometry [PDF]

, 2020
Glycans possess unparalleled structural complexity arising from chemically similar monosaccharide building blocks, configurations of anomeric linkages and different branching patterns, potentially giving rise to many isomers.
Corzana, Francisco [0000-0001-5597-8127], Gonzalo Jiménez-Osés, Unione, Luca, Sastre Toraño, Javier, Javier Sastre Toraño, Li, Tiehai, Juan M. Falcon‐Perez, Corzana, Francisco, Luca Unione, Boons, Geert-Jan [0000-0003-3111-5954], Francisco Corzana, Unione, Luca [0000-0002-8724-8783], Somovilla, Victor J, Aizpurua-Olaizola, Oier [0000-0003-2321-2113], Falcon-Perez, Juan M, Geert‐Jan Boons, Falcon-Perez, Juan M., Na Wei, Geert-Jan Boons, Wei, Na, Juan M. Falcon-Perez, Oier Aizpurua-Olaizola, Jiménez-Osés, Gonzalo [0000-0003-0105-4337], Oier Aizpurua‐Olaizola, Tiehai Li, Somovilla, Victor J., Victor J. Somovilla, Aizpurua-Olaizola, Oier, Gonzalo Jiménez‐Osés, Jiménez-Osés, Gonzalo, Boons, Geert-Jan   +30 more
core   +1 more source

Approaching the secrets of N-glycosylation in Aspergillus fumigatus [PDF]

, 2010
The mannosyltransferase Och1 is the key enzyme for synthesis of elaborated protein N-glycans in yeast. In filamentous fungi genes implicated in outer chain formation are present, but their function is unclear.
Engel Jakob, Echtenacher, Bernd, Bernd Echtenacher, Ilse Jacobsen, Kotz, Andrea, Routier Françoise H., Wagener, Johannes, Routier, Françoise H., Engel, Jakob, Kotz Andrea, Ebel Frank, Frank Ebel, Jacobsen Ilse, Françoise H Routier, Wagener Johannes, Heesemann, Jürgen, Johannes Wagener, Nielsen, Kirsten, Echtenacher Bernd, Jakob Engel, Ebel, Frank, Jürgen Heesemann, Heesemann Jürgen, Andrea Kotz, Françoise H. Routier, Jacobsen, Ilse   +25 more
core   +2 more sources