Results 11 to 20 of about 88,542 (309)
Nanomaterials, 2020 This review paper comprehensively summarizes advances made in the design of glycan nanobiosensors using diverse forms of nanomaterials. In particular, the paper covers the application of gold nanoparticles, quantum dots, magnetic nanoparticles, carbon nanoparticles, hybrid types of nanoparticles, proteins as nanoscaffolds and various nanoscale-based ...
Filip Kveton +3 more
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Glycans in autophagy, endocytosis and lysosomal functions [PDF]
, 2021 Glycans have been shown to function as versatile molecular signals in cells. This prompted us to look at their roles in endocytosis, endolysosomal system and autophagy. We start by introducing the cell biological aspects of these pathways, the concept of
Aureli Massimo +11 more
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Glycans and Glycan-Binding Proteins in Atherosclerosis [PDF]
Thrombosis and Haemostasis, 2019 AbstractComplex glycans are readily accessible on the endothelium and on cell and plasma components. They interact with glycan-binding proteins which translate their structure into function. Advanced analytical tools are available to investigate their structure and functional interactions.
Veit Eckardt +2 more
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Science Immunology, 2018 The gut commensal bacterium Bifidobacterium bifidum promotes immune tolerance by facilitating the induction of colonic regulatory T cells. See related Research Article by Verma et al .
Katherine A. Kaiser, Nicholas Arpaia
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Glycan profiling of the gut microbiota by Glycan-seq
ISME Communications, 2022 Abstract Bacterial glycans modulate the cross talk between the gut microbiota and its host. However, little is known about these glycans because of the lack of appropriate technology to study them. In this study, we applied Glycan-seq technology for glycan profiling of the intact gut microbiota of mice. The evaluation of cultured gram-
Lalhaba Oinam +2 more
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Glycan Fingerprints: Calculating Diversity in Glycan Libraries [PDF]
ACS Chemical Biology, 2012 Carbohydrate libraries printed in glycan micorarray format have had a great impact on the high-throughput analysis of the specificity of a wide range of mammalian, plant, and bacterial lectins. Chemical and chemo-enzymatic synthesis allows the construction of diverse glycan libraries but requires substantial effort and resources.
Rademacher, C., Paulson, J.
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Glycan microarrays of fluorescently-tagged natural glycans [PDF]
Glycoconjugate Journal, 2015 This review discusses the challenges facing research in 'functional glycomics' and the novel technologies that are being developed to advance the field. The structural complexity of glycans and glycoconjugates makes studies of both their structures and recognition difficult. However, these intricate structures can be captured from their natural sources,
Xuezheng, Song +3 more
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Cell-based glycan arrays for probing glycan–glycan binding protein interactions [PDF]
Nature Communications, 2018 AbstractGlycan microarrays provide a high-throughput means of profiling the interactions of glycan-binding proteins with their ligands. However, the construction of current glycan microarray platforms is time consuming and expensive. Here, we report a fast and cost-effective method for the assembly of cell-based glycan arrays to probe glycan–glycan ...
Jennie Grace Briard +4 more
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Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo-glycans
, 2023 Background: Pig-derived tissues could overcome the shortage of human donor organs in transplantation. However, the glycans with terminal α-Gal and Neu5Gc, which are synthesized by enzymes, encoded by the genes GGTA1 and CMAH, are known to play a major ...
Dietmar Böthig (21606075) +14 more
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Structural feature of N-glycans of bamboo shoot glycoproteins: useful source of plant antigenic N-glycans [PDF]
, 2017 An effective method to prepare plant complex type (PCT) N-glycans in large amounts has been required to evaluate their immunological activity. In this study, we found that glycoproteins in bamboo shoots predominantly carry PCT N-glycans including the ...
Megumi, Maeda +3 more
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