Results 11 to 20 of about 116,660 (304)
Multivalent glycan arrays [PDF]
Faraday Discussions, 2019 Glycan microarrays have become a powerful technology to study biological processes, such as cell–cell interaction, inflammation, and infections. Yet, several challenges, especially in multivalent display, remain.
Bordoni, Vittorio +5 more
core +5 more sources
Nanomaterials, 2020 This review paper comprehensively summarizes advances made in the design of glycan nanobiosensors using diverse forms of nanomaterials. In particular, the paper covers the application of gold nanoparticles, quantum dots, magnetic nanoparticles, carbon nanoparticles, hybrid types of nanoparticles, proteins as nanoscaffolds and various nanoscale-based ...
Filip Kveton +3 more
openaire +3 more sources
Glycan Fingerprints: Calculating Diversity in Glycan Libraries [PDF]
ACS Chemical Biology, 2012 Carbohydrate libraries printed in glycan micorarray format have had a great impact on the high-throughput analysis of the specificity of a wide range of mammalian, plant, and bacterial lectins. Chemical and chemo-enzymatic synthesis allows the construction of diverse glycan libraries but requires substantial effort and resources.
Rademacher, C., Paulson, J.
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Cell-based glycan arrays for probing glycan–glycan binding protein interactions [PDF]
Nature Communications, 2018 AbstractGlycan microarrays provide a high-throughput means of profiling the interactions of glycan-binding proteins with their ligands. However, the construction of current glycan microarray platforms is time consuming and expensive. Here, we report a fast and cost-effective method for the assembly of cell-based glycan arrays to probe glycan–glycan ...
Jennie Grace Briard +4 more
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Glycans and Glycan-Binding Proteins in Atherosclerosis [PDF]
Thrombosis and Haemostasis, 2019 AbstractComplex glycans are readily accessible on the endothelium and on cell and plasma components. They interact with glycan-binding proteins which translate their structure into function. Advanced analytical tools are available to investigate their structure and functional interactions.
Veit Eckardt +2 more
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Investigating virus–glycan interactions using glycan microarrays [PDF]
Current Opinion in Virology, 2014 While all viruses must transit the plasma membrane of mammalian cells to initiate infection, we know little about the complex processes involved in viral attachment, which commonly involve recognition of glycans by viral proteins. Glycan microarrays derived from both synthetic glycans and natural glycans isolated through shotgun glycomics approaches ...
David F, Smith, Richard D, Cummings
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Glycan microarrays of fluorescently-tagged natural glycans [PDF]
Glycoconjugate Journal, 2015 This review discusses the challenges facing research in 'functional glycomics' and the novel technologies that are being developed to advance the field. The structural complexity of glycans and glycoconjugates makes studies of both their structures and recognition difficult. However, these intricate structures can be captured from their natural sources,
Xuezheng, Song +3 more
openaire +2 more sources
Progesterone-Induced Sperm Release from the Oviduct Sperm Reservoir
Cells, 2022 In mammalian females, after sperm are deposited in the reproductive tract, a fraction of sperm migrates to the lower oviduct (isthmus) and forms a sperm storage site known as the functional sperm reservoir.
Supipi Mirihagalle +2 more
doaj +1 more source
Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking [PDF]
, 2009 We have previously reported that galectin-4, a tandem repeat-type galectin, regulates the raft-dependent delivery of glycoproteins to the apical brush border membrane of enterocyte-like HT-29 cells.
Altschuler Y. +8 more
core +3 more sources
Viruses, 2018 Glycans are, with nucleic acids, proteins and lipids, one of the four founding structures of cellular life. Due to their non-template synthesis, they are inherently heterogeneous and difficult to study with regards to their structure and function.
Thilo Stehle +3 more
doaj +1 more source