Results 161 to 170 of about 86,469 (209)
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Glycans in Regeneration

ACS Chemical Biology, 2013
Glycans participate in many key cellular processes during development and in physiology and disease. In this review, the functional role of various glycans in the regeneration of neurons and body parts in adult metazoans is discussed. Understanding glycosylation may facilitate research in the field of stem cell biology and regenerative medicine.
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Synthetic Glycan Microarrays

2016
Structurally diverse glycans are expressed by all animate beings and exert diverse biological functions through specific interactions with glycan binding proteins (GBPs). In humans, glycan-GBP interactions are implicated in many disease-relevant processes in development, infection and immune response to bacterial and viral pathogens. Recent progress in
Bröcker, F., Seeberger, P.
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Using the glycan toolbox for pathogenic interventions and glycan immunotherapy

Current Opinion in Biotechnology, 2018
Glycans play a crucial role to discern between self and foreign entities by providing key recognition elements for C-type lectin receptors (CLRs) and Siglec receptors expressed on immune cells. The glycan recognition of CLRs has illustrated a potent immune modulatory role affecting not only innate pathogen binding and immune signalling, but also ...
RJ Eveline Li   +2 more
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N-glycans of bovine submaxillary mucin contain core-fucosylated and sulfated glycans but not sialylated glycans

International Journal of Biological Macromolecules, 2019
Bovine submaxillary mucin (BSM) is a heavily-glycosylated macromolecular (approximately 4 MDa) protein and is used in various biomaterial applications in light of its high viscosity and biocompatibility, in addition to use as a biochemical substrate or inhibitor as a result of its abundant O-glycans.
Jihye, Kim   +11 more
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Glycans of myelin proteins

Journal of Neuroscience Research, 2014
Human P0 is the main myelin glycoprotein of the peripheral nervous system. It can bind six different glycans, all linked to Asn93, the unique glycosylation site. Other myelin glycoproteins, also with a single glycosylation site (PMP22 at Asn36, MOG at Asn31), bind only one glycan.
Sedzik J   +2 more
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Sulfated glycans in inflammation

European Journal of Medicinal Chemistry, 2015
Sulfated glycans such as glycosaminoglycans on proteoglycans are key players in both molecular and cellular events of inflammation. They participate in leukocyte rolling along the endothelial surface of inflamed sites; chemokine regulation and its consequential functions in leukocyte guidance, migration and activation; leukocyte transendothelial ...
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Capturing glycans

Nature Reviews Microbiology, 2023
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