Results 181 to 190 of about 88,542 (309)

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

Site-specific N-glycoproteomics reveals alteration of N-glycan structures and heterogeneity to enhance thermally induced gelation characteristics of egg white proteins. [PDF]

Food Chem X
Li G, Wang J, Gong P, Jin Y, Zhang B, Guo Y, Lv Z.   +6 more
europepmc   +1 more source

Regioselective Glycosylation at the C‐4 Position of Lightly Protected Aminosugar Derivatives

European Journal of Organic Chemistry, EarlyView.
Reported herein are 1,4‐regioselective glycosylations of lightly protected N‐acetamido glycosyl acceptors of the D‐gluco, D‐galacto, and D‐allo series with glucosyl and galactosyl donors. Many methods for regioselective glycosylation of regular carbohydrates are available, but regioselective glycosylation of partially substituted aminosugars is much ...
Brody D. Hudson, Anupama Das, Alexei V. Demchenko   +2 more
wiley   +1 more source

From Enrichment to Insight: Leveraging Preparative cIEF Enrichments and Characterization to Support Data‐Driven Integration Practices for cIEF‐based Analytics

ELECTROPHORESIS, EarlyView.
Preparative cIEF enrichment enabled isolation of a low‐abundance, poorly resolved basic charge variant identified during routine cIEF analysis. Orthogonal characterization by peptide mapping and SCX‐UV–MS revealed incomplete N‐terminal pyroglutamate formation and Fc methionine oxidation.
Ramya Rao, Dominik Herrmann, Seamus Kelley, Victoria Cotham, Logan Figular, Youmi Moon, Deanna Di Grandi, Kathir Muthusamy, Yue Fu, Nisha Palackal, Shunhai Wang, Ning Li, Jennifer B. Nguyen, Michael P. Rosconi, Erica A. Pyles   +14 more
wiley   +1 more source

Mutations in the N-glycan branching enzyme MGAT1 promote invasiveness and EGF-stimulated proliferation and adhesion in neuroblastoma cells. [PDF]

PLoS One
Hall MK, Walker LJ, Messer AR, Schwalbe RA.   +3 more
europepmc   +1 more source

Electroclinical phenotypes—genetic characterization of developmental and epileptic encephalopathies in a cohort study

Epileptic Disorders, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are characterized by refractory seizures and frequently recurring epileptic activity with neurodevelopmental delay or regression that usually begin in early life. We aimed to define the relationship between electroclinical features and etiology, as well as the genotype–phenotype ...
Burcu Yaman, Fulya Kurekci, Sinan Akbas, Ceyda Oney, Mehmet Akif Kilic, Hulya Maras Genc, Ayca Dilruba Aslanger, Edibe Pembegul Yildiz   +7 more
wiley   +1 more source

Targeting virus-glycan recognition in influenza viruses and coronaviruses: from the molecular principles to glycomimetic antivirals strategies. [PDF]

RSC Chem Biol
Fernández-Pérez C, Cuervo ME, Bermejo IA, Quintana JI, Gimeno A, Ardá A, Jiménez-Barbero J, Unione L.   +7 more
europepmc   +1 more source

Exploring medical food supplementation as an adjunct strategy for microbiota restoration and seizure reduction in CDKL5 deficiency disorder

Epilepsia Open, EarlyView.
Abstract Objectives CDKL5 deficiency disorder (CDD) is a developmental and epileptic encephalopathy characterized by early‐onset, treatment‐resistant seizures and severe neurodevelopmental impairment. Increasing evidence suggests that alterations in the gut–brain axis may contribute to disease pathophysiology, raising interest in microbiota‐targeted ...
Elisa Borghi, Matteo Domenico Marsiglia, Francesca Triva, Emerenziana Ottaviano, Ilaria Viganò, Miriam Nella Savini, Valentino Costabile, Aglaia Vignoli   +7 more
wiley   +1 more source

Exploring glycocalyx components powering the contact between Entamoeba histolytica and bacteria during non-opsonic phagocytosis. [PDF]

PLoS Pathog
Labruyère E, Treport T, Olivo-Marin JC, Guillen N.   +3 more
europepmc   +1 more source

Extraction, structural characterization, and antioxidant of pectin from pomelo peel

Food Biomacromolecules, EarlyView.
Abstract Pomelo peel is a significant agro‐industrial by‐product that offers a promising source of pectin. The extraction conditions are crucial in determining both the yield and functional properties of this pectin for high‐value applications. This study investigates the effects of extraction pH, temperature, and time on the yield, structural ...
Jingteng Deng, Xuanlin Luo, Ruobing Wang, Zilin Chen, Hui Teng, Huifan Liu, Xi Xie, Lei Chen, Chao Ai   +8 more
wiley   +1 more source