DJ-1 as a deglycating enzyme: A unique function to explain a multifaceted protein? [PDF]
, 2017 The recently reported deglycating activity of DJ-1 reconciles several features previously described for the protein. The deglycating activity reported for DJ-1 may explain its different subcellular localizations, indeed the protein has been found in the ...
Bisaglia, Marco, DE LAZZARI, Federica
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Glycated albumin and glycated hemoglobin- A comparison
International Journal of Biomedical Research, 2013 The progressive complications of unmanaged diabetes include heart disease, blindness, kidney failure, amputation of extremities due to circulation problems, and nerve disorders, as well as other chronic conditions. Decades of research have established that prolonged exposure to excess glucose is the cause of diabetes complications, and that long-term ...
Brijesh Mukherjee +2 more
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Methylglyoxal induces platelet hyperaggregation and reduces thrombus stability by activating PKC and inhibiting PI3K/Akt pathway [PDF]
, 2013 Diabetes is characterized by a dysregulation of glucose homeostasis and platelets from patients with diabetes are known to be hyper-reactive and contribute to the accelerated development of vascular diseases.
Elgheznawy, Amro +4 more
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Molecules, 2018 Advanced Glycation End-Products (AGEs) are created in the last step of protein glycation and can be a factor in aging and in the development or worsening of many degenerative diseases (diabetes, chronic kidney disease, atherosclerosis, Alzheimer’s ...
Agnieszka Szkudlarek +2 more
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Prevention of Protein Glycation by Natural Compounds [PDF]
, 2015 Non-enzymatic protein glycosylation (glycation) contributes to many diseases and aging of organisms. It can be expected that inhibition of glycation may prolong the lifespan.
Bartosz, Grzegorz +1 more
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Selective disappearance of individuals with high levels of glycated haemoglobin in a free-living bird [PDF]
, 2016 This work was supported by the ANR (ANR-06-JCJC0082 to B.D.), the CNRS (PEPS INEE and PICS France–Switzerland to B.D.), the French Ministe`re de l’Enseignement Supe´rieur et de la Recherche (PhD fellowship to C.R.), the Re´gion Rhoˆne-Alpes (Explora’doc ...
Bize, Pierre +4 more
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SERS Sensor for Human Glycated Albumin Direct Assay Based on Machine Learning Methods
Chemosensors, 2022 In this study, a non-labeled sensor system for direct determining human glycated albumin levels for medical application is proposed. Using machine learning methods applied to surface-enhanced Raman scattering (SERS) spectra of human glycated albumin and ...
Ekaterina A. Slipchenko +9 more
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In vitro determination of hemoglobin A1c for diabetes diagnosis and management: technology update [PDF]
, 2014 It is fascinating to consider the analytical improvements that have occurred since glycated hemoglobin was first used in routine clinical laboratories for diabetes monitoring around 1977; at that time methods displayed poor precision, there were no ...
English, Emma +2 more
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Influence of biological variations and sample handling on measured microalbuminuria in diabetic patients [PDF]
, 1992 Five immunochemical assays for determining low concentrations of albumin were investigated. These were a radioimmunoassay (RIA); turbidimetric immunoassays (TIA) both according to end-point measuring principle on a Cobas Fara and Hitachi 717 analysers ...
Cowell +19 more
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Urinary proteomics for prediction of mortality in patients with type 2 diabetes and microalbuminuria [PDF]
, 2018 Background: The urinary proteomic classifier CKD273 has shown promise for prediction of progressive diabetic nephropathy (DN). Whether it is also a determinant of mortality and cardiovascular disease in patients with microalbuminuria (MA) is unknown.
Currie, Gemma E. +11 more
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