Results 271 to 280 of about 134,228 (341)

Multi-dimensional role of AGEs in periodontitis: from matrix remodeling to neuro-immune crosstalk. [PDF]

Front Immunol
Dong YL, Lin H, Wen T, Guo ZL.
europepmc   +1 more source

T1WI‐SWI Dual Modal Magnetic Resonance Nanoprobes for Accurate Diagnosis of Early Stage Alzheimer's Disease

Advanced Science, Volume 13, Issue 1, 5 January 2026.
We developed a smart MRI nanoprobe targeting BACE1 and Aβ plaques. It crosses the blood‐brain barrier. Upon encountering BACE1, the probe is cleaved, enabling T1WI imaging detection. Subsequent reaction with ONOO− induces probe aggregation, enhancing magnetic susceptibility for sensitive SWI imaging of Aβ plaques.
Minghua Li, Aijun Shen, Xiaolong Gao, Chao Lin, Zongliang Huang, Qi Lv, Junjun Tang, Xiaolong Ma, Jiong Ni, Ju Tian, Jiaqi Wu, Xiaowen Xu, Wei Wang, Peijun Wang   +13 more
wiley   +1 more source

Fibrinogen glycosylation and glycation: molecular insights into thrombosis and vascular disease. [PDF]

Front Mol Biosci
Borghi S, Nencini F, Giurranna E, Barbaro I, Taddei N, Fiorillo C, Becatti M.   +6 more
europepmc   +1 more source

Glycation Stress–Driven Transcriptomic Signature Predicts Survival Benefit from Adjuvant Gemcitabine in Resectable Pancreatic Cancer

Azurmendi Senar, Oier, Stosic, Kosta, Arsenijevic, Tatjana, Van Laethem, Jean-Luc, Navez, Julie   +4 more
openalex   +1 more source

NOX2‐Driven Oxidative Stress Promotes EndMT and Uncouples Angiogenesis–Osteogenesis at the Bone–Implant Interface in Diabetes

Advanced Science, Volume 13, Issue 4, 19 January 2026.
NOX2‐driven oxidative stress disrupts angiogenesis–osteogenesis coupling at the diabetic bone–implant interface. Pharmacologic inhibition and endothelial‐specific NOX2 knockout restore type‐H endothelium, suppress EndMT, and improve osseointegration.
Zimei Wu, Qiaodan Hou, Yang Liu, Tingting Chen, Kunkun Yang, Luyao Li, Lin Wang   +6 more
wiley   +1 more source

Association of hemoglobin glycation index with the severity and mortality of cardiovascular-kidney-metabolic syndrome: a population-based cohort study. [PDF]

Cardiovasc Diabetol Endocrinol Rep
Geng L, Diao X, Yu HJ, Xu A.
europepmc   +1 more source

Associations between metabolic syndrome and regional brain iron depositions and cognitive function in middle‐aged and older adults: A two multinational cohort study

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION The alterations of regional brain iron in patients with metabolic syndrome (Mets) and its relationship with cognitive function remain unclear. METHODS These analyses utilized data from two prospective cohorts, from the UK Biobank (UKB) (21,346 participants) and from Jinan, China (224 participants). We capitalized brain iron in the
Xinyue Zhang, Linfeng Yang, Na Wang, Yuanyuan Wang, Qihao Zhang, Zhenyu Cheng, Yiwen Chen, Pengcheng Liang, Meng Li, Lingfei Guo, Changhu Liang   +10 more
wiley   +1 more source

Clinical and Experimental Studies of Structural Valve Degeneration of Bovine Jugular Vein Valves: Mitigation with Polyoxazoline Modification. [PDF]

Pediatr Cardiol
Moroi MK, Kosuri Y, Singh SK, Xue Y, Zakharchenko A, Karcher C, Martinez A, Patel K, Abramov A, Carreon CK, Sanders SP, Levy RJ, Ferrari G.   +12 more
europepmc   +1 more source

Therapeutic Potential of Resveratrol in Cancer and Neurodegenerative Disorders: A Current Review

BioFactors, Volume 52, Issue 1, January/February 2026.
Resveratrol induces the expressions of TP53, NRF2, and JDP2 axis in cancer cells to control ROS balance in mitochondria. The antioxidation responses were induced through SRIT1/3, HDAC, STAT3, TGFβ, and so on, to trigger the inflammation, and NFkB response to lead to the cell death of cancers or neuro‐damaged cells.
Kenly Wuputra, Chia‐Che Ku, Ying‐Chu Lin, Yi‐Chun Tsai, Deng‐Chyang Wu, Yukio Mitsui, Maki Satou, Yuuki Tanaka, Shigeo Saito, Kazunari K. Yokoyama   +9 more
wiley   +1 more source

Comment on: "Association Between the Hemoglobin Glycation Index (HGI) and Risk of Diabetic Nephropathy: A Retrospective Cohort Study" [Response to Letter]. [PDF]

Diabetes Metab Syndr Obes
Zhou W, Zhang L, Liu T.
europepmc   +1 more source