Results 291 to 300 of about 307,887 (342)

Continuous glucose monitoring‐derived time in range is associated with changes in cognitive function test scores in Japanese patients with type 2 diabetes mellitus

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Type 2 diabetes mellitus (T2DM) is known to be a risk factor for cognitive dysfunction and dementia. Time in range (TIR), which is derived from continuous glucose monitoring (CGM), has been widely used as an indicator of the quality of glycemic control. While cross‐sectional studies have reported an association between CGM‐derived TIR and
Maki Inoue   +57 more
wiley   +1 more source

Exploring the genomic and transcriptomic profiles of glycemic traits and drug repurposing. [PDF]

open access: yesJ Biomed Sci
Lin MR   +6 more
europepmc   +1 more source

Efficacy and safety of danuglipron (PF‐06882961) in adults with obesity: A randomized, placebo‐controlled, dose‐ranging phase 2b study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims This randomized, double‐blind, placebo‐controlled Phase 2b study aimed to assess the efficacy, safety, and tolerability of danuglipron (PF‐06882961), an oral small‐molecule glucagon‐like peptide‐1 (GLP‐1) receptor agonist, in adults with obesity. Materials and Methods Eligible participants (aged 18–75 years; with obesity, without diabetes)
Clare Buckeridge   +9 more
wiley   +1 more source

Emotional distress as a therapeutic target against persistent poor glycaemic control in subjects with type 1 diabetes: A systematic review

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Persistent poor glycaemic control is frequently observed in subjects with type 1 diabetes (T1D). The burden of diabetes self‐management, fear of hypoglycaemia, and other diabetes‐specific stressors are associated with diabetes distress and poor glycaemic control.
Sylvia Franc, Guillaume Charpentier
wiley   +1 more source

Long‐term preservation of kidney function with SGLT‐2 inhibitors versus comparator drugs in people with type 2 diabetes and chronic kidney disease

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Chronic kidney disease (CKD) is a prevalent and serious complication of type 2 diabetes (T2D). This study aims to evaluate kidney outcomes in a real‐world cohort of patients with T2D and CKD who received SGLT2 inhibitors (SGLT2i) or other glucose‐lowering medications (GLM).
Gian Paolo Fadini   +87 more
wiley   +1 more source

Cellular composition and transcriptomics of subcutaneous adipose tissue linked to blood glycated haemoglobin

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Immune cell overrepresentation in SAT in subjects with high HbA1c was accompanied by decreased adipocytes, smooth muscle, pericytes and other endothelial cell numbers. Immune system and inflammation‐related pathways, cellular senescence and telomere‐related pathways, nervous system development and extracellular matrix organization were associated with ...
Sara Paulí   +26 more
wiley   +1 more source

Do the Types of Dietary Carbohydrate and Protein Affect Postprandial Glycemia in Type 1 Diabetes? [PDF]

open access: yesNutrients
Li X   +12 more
europepmc   +1 more source

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