1‐Deoxynojirimycin Alleviates Osteoporosis via Promoting LRP5 Signaling in Osteoblasts and BMSCs
Graphical abstract of the potential mechanism by which DNJ promotes osteogenic differentiation in osteoblasts. DNJ improves LRP5 activity by directly binding to its extracellular domain, thereby facilitating β‐catenin's translocation from the cytoplasm to the nucleus.
Kainong Sun +10 more
wiley +1 more source
Knowledge, Attitudes, and Dietary Practices Regarding Low Glycemic Index Foods Among Urban Working Women in Western Province, Sri Lanka. [PDF]
Jayasinghe T +4 more
europepmc +1 more source
Schematic overview of the in vivo and in vitro experimental designs used to investigate the protective effects of oxyberberine (OBB) against type 2 diabetic osteoporosis, including C‐Z treatment, Sirt3 knockdown, and assessments of osteogenesis, autophagy, oxidative stress, and ferroptosis. ABSTRACT Type 2 diabetic osteoporosis (T2DOP) is characterized
Jianan Huang +10 more
wiley +1 more source
Diet Quality and Nutritional Value in Children and Adolescents with Excess Body Weight and Dyslipidemia Undergoing Low-Glycemic Index or Standard Diet. [PDF]
Bondyra-Wiśniewska B, Harton A.
europepmc +1 more source
In this systematic review and meta‐analysis of four randomized controlled trials (n = 178) of Iranian propolis in adults with MASLD, propolis supplementation was associated with improvement in ultrasound‐assessed hepatic steatosis (three trials, n = 156; RR 2.41, 95% CI 1.59–3.66) and a modest reduction in fasting glucose, with no significant effects ...
Ting‐An Kuo +4 more
wiley +1 more source
Effect of the Replacement of Corn (<i>Zea mays</i>) by Chickpea (<i>Cicer arietinum</i>) and Rice (<i>Oryza sativa</i>) in Extruded Snacks on Protein Digestibility, Mineral Bioaccessibility and Estimated Glycemic Index. [PDF]
García-Cordero AL +7 more
europepmc +1 more source
Fenestrated Microneedle Biosensor for Continuous In Vivo Lactate Monitoring in Interstitial Fluid
A fenestrated microneedle biosensor enables continuous transdermal monitoring of lactate in interstitial fluid while protecting the functional sensing interface during insertion into the skin. The platform delivers sensitive electrochemical lactate detection and distinguishes metabolic profiles in healthy and type 2 diabetic‐obese mice, and captures ...
Masoud Khazaei +5 more
wiley +1 more source
Effects of Chemical Composition and Intramolecular Structural Characteristics of Black Rice Varieties on Glycemic Index and Their Regulation Under Different Processing Conditions. [PDF]
Wang D +8 more
europepmc +1 more source
Anti‐obesity medications and incident ocular outcomes: A systematic review and network meta‐analysis
In this systematic review and network meta‑analysis of 140 studies, anti‑obesity medications showed heterogeneous ocular safety profiles. Semaglutide was associated with higher NAION risk (observational data), whereas dual/multi‑agonists and glucagon‐like peptide‐1 receptor agonists demonstrated favourable glaucoma and overall ocular outcomes ...
Linge Jian +5 more
wiley +1 more source

