Results 41 to 50 of about 90,308 (265)

Materials and System Design for Self‐Decision Bioelectronic Systems

Advanced Materials, EarlyView.
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng, Hong Liu, Yongheng Zhang, Youbin Zheng, Xuyin Ding, Mengni Zhu, Guoyue Shi, Yan Wang, Hossam Haick, Min Zhang   +9 more
wiley   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Triglyceride Glucose Index as A Promising Biomarker for Glycemic Control in Type 2 Diabetic Patients [PDF]

, 2023
Samar Kamalelden, Mohamed Mokhtar Mohamed, Fatma Kamel, Mervat El, Shahat Khalifa, El Wakeel, Shaymaa Hafeez, S Keating, J Plutzky, A El-Osta, S Saha, P Schwarz, L Er, S Wu, H Chou, L Hsu, M Teng, Y Sun, Y Ko, A Vasques, F Novaes, M De Oliveira, J Souza, A Yamanaka, J Pareja, M Tambascia, M Saad, B Geloneze, F Guerrero-Romero, L Simental-Menda, M Gonzalez-Ortiz, E Martnez-Abundis, M Ramos-Zavala, S Hernandez-Gonzalez, O Jacques-Camarena, M Rodrguez-Morn, Ada, W Friedewald, R Levy, D Fredrickson, D Matthews, J Hosker, A Rudenski, B Naylor, D Treacher, R Turner, S Zhang, T Du, J Zhang, H Lu, X Lin, J Xie, Y Yang, X Yu, S Alam, M Hasan, S Neaz, N Hussain, M Hossain, T Rahman, H Holmer, L Ogden, B Burda, S Norris, S Khan, F Sobia, N Niazi, S Manzoor, N Fazal, F Ahmad, B Park, H Lee, Y Lee, K Souliotis, A Koutsovasilis, G Vatheia, F Othman, N Afiffy, A Melegy, O Mostafa, B Yeap, K Mccaul, L Flicker, L Cheng, W Wang, S Lim, V Wu, S Tangvarasittichai, H Awadalla, S Noor, W Elmadhoun, S Bushara, A Almobarak, A Sulaiman, M Ahmed, N Rabbani, M Chittari, C Bodmer, D Zehnder, A Ceriello   +99 more
openalex   +1 more source

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

Advanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue, Jialu Zhuang, Taotao Fan, Songtao Tang, Junjun Wang, Xiaohui Liu, Jian Liu, Jin Shi, Jiaji Li, Wanjun Li, Danyou Hu, Xiaoqian Zhang, Hua Wang, Guiyang Zhang   +13 more
wiley   +1 more source

The Association between Dietary Glycemic Index, Glycemic Load and Children Obesity: A Review of Published Papers

مجله دانشکده پزشکی اصفهان, 2012
Background: Many studies were conducted to evaluate the association between dietary glycemic index, glycemic load and children obesity. The aim of this study was to review these studies.
Seyed Mohammad Hossein Rouhani, Mahin Hashemipour, Roya Kelishadi, Ahmad Esmaillzadeh, Leila Azadbakht   +4 more
doaj  

A Time‐Programmed Bilayer Wound Dressing for Dynamic Microenvironment Modulation and Full‐Thickness Regeneration in Diabetic Wounds

Advanced Science, EarlyView.
The Polyphenol+PDGF‐BB scaffold fabrication (Panel A) and its dual wound healing effects (Panel B: anti‐inflammation and accelerated tissue remodeling). ABSTRACT Chronic diabetic wounds suffer from dysfunctional repair programs due to accumulated advanced glycation end products (AGEs) and persistent inflammation in hyperglycemic microenvironments ...
Lei Yi, Wanqian Li, Ying Duanmu, Zihan Zhang, Shixuan Chen, Shichu Xiao, Lei Du, Miaomiao Wei   +7 more
wiley   +1 more source

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source

Glycemic deviation index: a novel method of integrating glycemic numerical value and variability

BMC Endocrine Disorders, 2021
Background There are many continuous blood glucose monitoring (CGM) data-based indicators, and most of these focus on a single characteristic of abnormal blood glucose.
Yizhou Zou, Wanli Wang, Dongmei Zheng, Xu Hou   +3 more
doaj   +1 more source

Label‐Free Leukocyte Biophysical Profiling Using Impedance‐Deformability Cytometry for Rapid Cardiovascular Risk Stratification

Advanced Science, EarlyView.
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He, Hui Min Tay, Feng Chen, Hong Sheng Cheng, Liang De Wang, Qiqi Nam, Arunachalam Thannirmalai, Lingyan Gong, Aram J. Chung, Nguan Soon Tan, King Ho Holden Li, Rinkoo Dalan, Siu Ling Wong, Han Wei Hou   +13 more
wiley   +1 more source

Mussel‐Bioinspired Edible Ca2+‐Crosslinked Alginate Hydrogel Electrodes for Glucose Gastrointestinal Monitoring

Advanced Science, EarlyView.
A fully edible soft electrode is engineered from Ca2⁺‐crosslinked alginate integrated with polydopamine, silver nanoparticles, and food‐grade glucose oxidase. The hybrid hydrogel combines ionic and electronic conduction, enabling efficient glucose‐to‐H2O2 conversion and catalytic reduction in simulated intestinal fluid.
Verdiana Marchianò, Claudio Pellegrini, Angelo Tricase, Eleonora Macchia, Andrea Brattelli, Luigi Gentile, Patrizia Nadia Hanieh, Noemi Fiaschini, Antonio Rinaldi, Luisa Torsi, Paolo Bollella   +10 more
wiley   +1 more source