Glycemic index, nutrient density, and promotion of aberrant crypt foci in rat colon [PDF]
We speculated that a diet with a high glycemic index (GI), or a diet with a low nutrient density (nutrient-to-calorie ratio), would enhance colon carcinogenesis, presuma-bly via increased insulin resistance.
Peiffer, Ginette +2 more
core
Programmable Self‐Heating Microneedle Patch for on‐Demand Postprandial Glucose Management
A programmable self‐heating microneedle patch enables on‐demand, timed‐sequence insulin delivery via user‐triggered quadrant activation. Each activation generates localized heat that melts a phase‐change barrier, accelerating drug release. In diabetic rats, sequential quadrant activation counteracts four meal‐mimicking glucose spikes over 24 h without ...
Yang Zhao +9 more
wiley +1 more source
Background: Many studies were conducted to evaluate the association between dietary glycemic index, glycemic load and children obesity. The aim of this study was to review these studies.
Seyed Mohammad Hossein Rouhani +4 more
doaj
The effect of porang flour (Amorphophallus muelleri Blume) and mung bean flour (Vigna radiata) substitution with the addition of moringa leaves (Moringa oleifera) on glycemic index of rice paper [PDF]
Diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose levels, both in fasting and postprandial conditions. Type 2 diabetes mellitus is a degenerative disease closely associated with dietary patterns.
S. Amelia +9 more
doaj +2 more sources
Immune Biomarkers of Islet Transplant Rejection Revealed by Synthetic Immunological Niche
A subcutaneous synthetic immunological niche (IN) enables serial, minimally invasive monitoring of immune responses after islet transplantation. Flow cytometry and transcriptomic profiling of the IN reveal immune‐cell programs associated with graft acceptance and distinct types of rejection.
Jyotirmoy Roy +8 more
wiley +1 more source
The Glycemic Index (GI) is a rating system that ranks carbohydrate-containing foods according to their postprandial blood glucose response relative to the same quantity of available carbohydrate of a standard such as white bread or glucose. The concept of GI was first introduced in the early 80's by Jenkins and coworkers.
Rahelić, Dario +8 more
openaire +3 more sources
Loss of Intestinal MSTN Promotes GLP‐1 Secretion Through SGLT1 Palmitoylation
Intestinal MSTN deficiency enhances glucose‐stimulated GLP‐1 secretion and glucose tolerance in high‐fat diet‐fed mice. Mechanistically, loss of MSTN promotes YY1‐associated ZDHHC20 expression, increasing SGLT1 S‐palmitoylation at Cys301 and its plasma membrane localization in L cells.
Sheng‐Zhong Han +16 more
wiley +1 more source
Maternal Hyperglycemia Disrupts Cerebral Cortex Development Through the Foxp1‐Dll1‐Notch Axis
Maternal hyperglycemia disrupts offspring cortical development through a Foxp1–Dll1–Notch signaling axis. In a PGDM mouse model, intrauterine hyperglycemia decreases cortical thickness and perturbs neuronal layering by downregulating Foxp1, which transcriptionally regulates the Notch ligand Dll1.
Longkai He +12 more
wiley +1 more source
The effect of high carbohydrate meals with different glycemic indices on recovery of performance during prolonged intermittent high intensity shuttle running [PDF]
This study examined the effect of high carbohydrate meals with different glycemic indices (GI) on recovery of performance during prolonged intermittent high-intensity shuttle running.
Williams, Clyde +5 more
core
ABSTRACT Diabetic wounds are characterized by persistent inflammation and impaired immune resolution, yet the therapeutic translation of single‐cell atlases into rational immunomodulatory strategies remains limited. Here, integration of diabetic‐wound single‐cell transcriptomic datasets identifies a neutrophil subpopulation enriched in cluster of ...
Tairong Cui +12 more
wiley +1 more source

