Results 241 to 250 of about 1,279,661 (287)

Amylin: A Multi‐Functional Pancreatic Hormone—A Review

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Amylin is a pancreatic beta‐cell hormone that sits at a systems hub connecting key aspects of energy metabolism. Amylin physiologically controls satiation, slows gastric emptying and limits postprandial glucagon release, while its actions also link homeostatic eating controls with reward driven behaviours via defined central nervous system ...
Christelle Le Foll, Thomas A. Lutz
wiley   +1 more source

Dyslipidaemia, Chronic Kidney Disease and Diabetes Mellitus: A Triple Threat to Cardiovascular Health

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest, Priyanka Majety, Stéphanie B. Mayer, Om P. Ganda   +3 more
wiley   +1 more source

Bowel Obstruction/Ileus Associated With the Use of Glucagon‐Like Peptide‐1 Receptor Agonists: A Nationwide Database Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) use and the development of bowel obstruction/ileus remains unclear, and evidence for specific bowel obstruction/ileus subtypes remains limited. We examined the association between GLP‐1RA use and the incidence of bowel obstruction/ileus subtypes across different ...
Yuichiro Matsuo, Akira Okada, Takashi Sakamoto, Hideo Yasunaga   +3 more
wiley   +1 more source

Oleanolic Acid‐Enriched Olive Oil Attenuates Kidney Function Decline in Patients With Type 2 Diabetes: Results From the OLTRAD Randomised Controlled Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Chronic kidney disease (CKD) is a major complication of type 2 diabetes mellitus (T2DM), driven in part by oxidative stress and the accumulation of advanced glycation end products (AGEs). Oleanolic acid (OA), a natural triterpene present in olive‐derived matrices, may modulate AGE metabolism.
Aída García‐González, Alejandro Matamoros‐Domínguez, Juan Manuel Espinosa‐Cabello, Gisela Pérez‐Muñoz, Manuel Jesús León Aranda, María Del Carmen Roque‐Cuellar, Silvia García‐Rey, Andrés Jiménez‐Sánchez, Antonio Jesús Martínez‐Ortega, Miguel Ángel Mangas‐Cruz, Isabel Cerrillo, Javier S. Perona, Pedro Pablo García‐Luna, Elena María Yubero‐Serrano, José María Castellano   +14 more
wiley   +1 more source

Association of Lipid Ratios With Cardiovascular Outcomes in Type 2 Diabetes: A Population Cohort Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To identify low‐ and high‐risk intervals for major adverse cardiovascular events (MACE) and all‐cause mortality according to lipid ratios in adults with Type 2 diabetes mellitus (T2DM), stratified by sex. Materials and Methods We used primary care electronic health records from the Spanish National Health Service including 303 199 adults ...
Enrique Carretero‐Anibarro, Jose Antonio Quesada, Manuel A. Ruiz‐Quintero, Didac Mauricio, Kamlesh Khunti, Domingo Orozco‐Beltrán   +5 more
wiley   +1 more source

Ten‐Year Cost‐Effectiveness of the Risk Assessment and Management Programme—Diabetes Mellitus (RAMP‐DM) Relative to Usual Care in Hong Kong Public Primary Care: A Population‐Based Cohort Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The Risk Assessment and Management Programme—Diabetes Mellitus (RAMP‐DM) is a multidisciplinary, protocol‐driven, risk‐stratified care model integrated into public primary care in Hong Kong for patients with type 2 diabetes mellitus (T2DM).
Eric Ho Man Tang, Ivy Lynn Mak, Emily Tsui Yee Tse, Esther Yee Tak Yu, Julie Yun Chen, Weng Yee Chin, David Vai Kiong Chao, Wendy Wing Sze Tsui, Tony King Hang Ha, Carlos King Ho Wong, Cindy Lo Kuen Lam, Eric Yuk Fai Wan   +11 more
wiley   +1 more source

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Glycemic Index, Glycemic Load, and Thrombogenesis

Seminars in Thrombosis and Hemostasis, 2009
Hyperglycemia and insulin resistance are independent risk factors for cardiovascular disease (CVD). Postprandial glycemic "spikes" adversely affect vascular structure and function via multiple mechanisms including oxidative stress, inflammation, low-density lipoprotein oxidation, protein glycation, and procoagulant activity.
Jennie, Brand-Miller, Scott, Dickinson, Alan, Barclay, Margaret, Allman-Farinelli   +3 more
openaire   +2 more sources

Glycemic indices, glycemic loads, and glycemic dietetics

Journal of Equine Veterinary Science, 2004
ow-glycemic diets based on the glycemic index (GI) are being recommended for the avoidance and amelioration of the numerous diseases in humans and animals that involve insulin resistance, such as diabetes mellitus type 2 and coronary heart disease in people and some forms of laminitis, exertional rhabdomyolysis, and developmental orthopedic disease in ...
David Kronfeld, Anne Rodiek, Carolyn Stull   +2 more
openaire   +1 more source

Glycemic index, glycemic load and risk of prostate cancer

International Journal of Cancer, 2004
AbstractDietary carbohydrates have different glycemic and insulinemic potentials depending on type (glycemic index, GI) and amount (glycemic load, GL) of carbohydrate consumed or both. Insulin in turn has been implicated as a risk factor for several cancers, including that of the prostate.
L. S. A. Augustin, C. Galeone, L. Dal Maso, C. Pelucchi, V. Ramazzotti, D. J. A. Jenkins, M. Montella, R. Talamini, E. Negri, S. Franceschi, C. La Vecchia   +10 more
openaire   +2 more sources

Dietary glycemic load, glycemic index and colorectal cancer risk: Results from the Netherlands Cohort Study

International Journal of Cancer, 2008
Since hyperinsulinemia is implicated in the development of colorectal cancer, determinants of serum insulin levels, like the glycemic load and the glycemic index of the diet, could influence cancer risk.
Piet van den Brandt, Mirjam Heinen, Matty Weijenberg   +2 more
exaly   +1 more source