Results 81 to 90 of about 2,836,117 (381)

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source

Glycemic index, glycemic load, and cancer risk: a meta-analysis [PDF]

The American Journal of Clinical Nutrition, 2008
Factors linked to glucose metabolism play an important role in the development of cancers, and both glycemic index (GI) and glycemic load (GL) have been investigated as potential etiologic factors.A meta-analysis was performed to explore the association between GI and GL and cancer risk from published studies.A comprehensive, systematic bibliographic ...
P. Gnagnarella, S. Gandini, C. La Vecchia, P. Maisonneuve   +3 more
openaire   +3 more sources

The Impact of Dietary Glycemic Index and Glycemic Load on Postprandial Lipid Kinetics, Dyslipidemia and Cardiovascular Risk

Nutrients, 2020
Many recent studies have acknowledged postprandial hypetriglyceridemia as a distinct risk factor for cardiovascular disease. This dysmetabolic state is the result of the hepatic overproduction of very low-density lipoproteins (VLDLs) and intestinal ...
V. Lambadiari, E. Korakas, V. Tsimihodimos   +2 more
semanticscholar   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

The effect of high carbohydrate meals with different glycemic indices on recovery of performance during prolonged intermittent high intensity shuttle running [PDF]

, 2006
This study examined the effect of high carbohydrate meals with different glycemic indices (GI) on recovery of performance during prolonged intermittent high-intensity shuttle running.
Chamberlain, Siobhan, Crews, Pippa, Erith, Samuel, Rushbury, Ian, Stevenson, Emma, Williams, Clyde   +5 more
core   +1 more source

Dietary Carbohydrate Intake, Dietary Glycemic Load and Outcomes of In Vitro Fertilization: Findings from an Observational Italian Cohort Study

Nutrients, 2020
In recent decades, increasing attention has been paid to the influence of diet on reproductive health. Carbohydrates in diet affect glucose metabolism and multiple evidences showed the key role of insulin sensitivity in regulating female fertility.
S. Noli, E. Ricci, S. Cipriani, S. Ferrari, Marta Castiglioni, I. La Vecchia, E. Somigliana, F. Parazzini   +7 more
semanticscholar   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

The association between dietary glycemic and insulin indices with incidence of cardiovascular disease: Tehran lipid and glucose study

BMC Public Health, 2020
Background The present study was conducted to investigate the association of dietary insulin index(II), insulin load(IL), glycemic index(GI), and glycemic load(GL) with the risk of cardiovascular disease(CVD).
Farshad Teymoori, Hossein Farhadnejad, Parvin Mirmiran, Milad Nazarzadeh, Fereidoun Azizi   +4 more
doaj   +1 more source

Glycemic Control and Acne: A Review [PDF]

International Journal of Nutrition Sciences, 2019
Acne as a chronic inflammation involves pilosebaceous unit and is associated with hyperkeratosis and sebaceous hypersecretion. A high glycemic index (GI) and glycemic load (GL) diet may stimulate acne proliferative pathways affecting biochemical factors ...
Zahra Setavand, Maryam Ekramzadeh
doaj   +1 more source

Glycemic index, glycemic load and thyroid cancer risk

Annals of Oncology, 2008
Risk of thyroid cancer has already been related to refined cereals and starch food, but the association has not been studied in terms of glycemic index (GI) and glycemic load (GL).We analyzed data from a case-control study conducted in Italy from 1986 to 1992 and including 399 histologically confirmed and incident cases of thyroid cancer and 616 ...
G. Randi, M. Ferraroni, R. Talamini, W. Garavello, S. Deandrea, A. Decarli, S. Franceschi, C. La Vecchia   +7 more
openaire   +2 more sources