Results 91 to 100 of about 1,258,513 (286)

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

open access: yesAdvanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai   +12 more
wiley   +1 more source

Glycemic variability and diabetic cardiac autonomic neuropathy [PDF]

open access: yes
Cardiac autonomic neuropathy (CAN) is closely associated with an approximately five-fold increase in the risk of cardiovascular mortality in patients with diabetes mellitus (DM). Impaired autonomic function of the cardiovascular system in DM, which leads
Y.I. Pavlovskiy   +3 more
core   +1 more source

Resistant Starch Dynamics in Whole‐Grain Cereals: How Processing and Macromolecular Interactions Shape Quality and Physiological Responses

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
This review explores how processing and macromolecular interactions shape resistant starch dynamics in whole‐grain cereals. It highlights how these transformations influence nutritional quality, digestion kinetics, and product properties, offering insights for designing stable health‐oriented whole‐grain foods with optimized functional benefits ...
Yuewen Tan   +4 more
wiley   +1 more source

Relationship Between Sedentary Time and Physical Activity With Glycemic Variability and Oxidative Stress [PDF]

open access: yes, 2020
Overweight and obesity is becoming more prevalent in adults across the United States. Overweight or obese adults are at an increased risk for the development of cardiometabolic disorders.
Sparks, Joshua Robert
core   +1 more source

The Role of Glucagon in Glycemic Variability in Type 1 Diabetes: A Narrative Review

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2021
Keyu Guo,* Qi Tian,* Lin Yang, Zhiguang Zhou National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of ...
Guo K, Tian Q, Yang L, Zhou Z
doaj  

Characterization of Daily Glycemic Variability in Subjects with Type 1 Diabetes Using a Mixture of Metrics [PDF]

open access: yes, 2019
International audienceBackground: Glycemic variability is an important component of glycemic control for patients with type 1 diabetes. The inadequacy of existing measurements lies in the fact that they view the variability from different aspects, so ...
Zheng, Fei   +6 more
core   +1 more source

Valorizing Food Waste (Banana Peel) Into an Edible Product: A Study on the Effect of Banana Peel Flour on the Physicochemical, Antioxidant, Textural, and Sensory Properties of Cookies

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
This study investigated the impact of banana peel flour (BPF) incorporation on cookies' nutritional, functional, physical, and antioxidant properties. The inclusion of BPF led to significant changes in the moisture, protein, crude fat, and ash contents of the developed cookies.
Km. Gudiya   +3 more
wiley   +1 more source

Starch digestibility modulation significantly improves glycemic variability in type 2 diabetic subjects: A pilot study

open access: yes, 2021
International audienceBACKGROUND AND AIMS: In type 2 diabetes (T2D) patients, the reduction of glycemic variability and postprandial glucose excursions is essential to limit diabetes complications, beyond HbA1c level.
Goux, A.   +10 more
core   +1 more source

Shared Metabolic–Proteinopathy Axis in Alzheimer's Disease and Parkinson's Disease: Evidence for a Convergent but Not Identical Disease Spectrum

open access: yesAGING MEDICINE, EarlyView.
This review explores the common pathological mechanisms underlying Alzheimer's disease (AD) and Parkinson's disease (PD), with an emphasis on glucose metabolism and insulin resistance. We examine how disruptions in glucose metabolism and insulin resistance influence the onset and advancement of both Alzheimer's disease (AD) and Parkinson's disease (PD).
Shun‐yu Yao   +5 more
wiley   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

open access: yesAGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

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