Results 71 to 80 of about 81,930 (267)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

The Mutagenic Potential Caused by the Emissions from Combustion of Crude Glycerin and Diesel Fuel

open access: yesBrazilian Archives of Biology and Technology, 2015
This study evaluated the use of crude glycerin as an alternative of energy generation to replace the traditional fuels. The Tradescantia stamen hair mutation assay (Trad-SH) was applied to study the mutagenic effects caused by the emissions generated in ...
Daniel Terruggi Mazak   +4 more
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Therapeutic benefits of glycerol in dry eye disease

open access: yesFrontiers in Medicine
Dry eye disease (DED) is one of the most commonly diagnosed eye disorders, with a prevalence ranging from 5 to 50%, depending on the geographic location.
Victoria Ronderos   +3 more
doaj   +1 more source

The use of capillary as a sensor of cavitation

open access: yes, 2002
The dramatic rise in height of the meniscus within a capillary, the other end of which is immersed in a liquid undergoing ultrasonic cavitation, represents a novel, robust and inexpensive method for monitoring cavitational activity.
Dezhkunov, N.V., Leighton, T.G.
core  

Far-field optical microscope with nanometer-scale resolution based on in-plane surface plasmon imaging

open access: yes, 2004
A new far-field optical microscopy technique capable of reaching nanometer-scale resolution has been developed recently using the in-plane image magnification by surface plasmon polaritons.
Burke J J   +10 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

ALTERNATIVE LUBRICATION MEDIUM FOR FOOD INDUSTRY [PDF]

open access: yesScientific Journal of Silesian University of Technology. Series Transport, 2014
The paper presents the results of research about alternative grease - glycerin. Tests were made on four-ball apparatus. Analysis of results confirms that glycerin can be used for lubrication in friction nodes.
Wojciech HORAK   +2 more
doaj  

Increased urinary losses in piglets fed diets containing high levels of glycerin

open access: yesRevista Brasileira de Zootecnia, 2019
This study evaluated the nutritional value of glycerin added to diets of weaned piglets and its effects on animal performance and urinary losses. Weaned piglets were individually housed in metabolic cages and fed diets in which a basal diet containing ...
Manuela Marques Fischer   +3 more
doaj   +1 more source

Peculiarities of spectra of induced emission of polymethine dye solutions at low temperatures [PDF]

open access: yes
Results from studying the induced emission spectra with monochromatic excitation (superluminescent regime) within a temperature range of 300 K - 5.2 K are presented.
Melishchuk, M. V.   +2 more
core   +1 more source

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