Results 221 to 230 of about 969,294 (383)

PSMD14 Stabilizes SLC7A11 to Ameliorate Glucocorticoid‐Induced Osteoporosis by Suppressing Osteocyte Ferroptosis

Advanced Science, EarlyView.
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi, Qian Tang, Sunren Sheng, Hongyi Jiang, Chen Jin, Chencheng Zhou, Chenglong Xie, Lin Zheng, Di Zhang, Hui Xu, Cong Xu, Haiwei Ma, Guangheng Xiang, Wenfei Ni, Xiaoyun Pan, Lei Yang, Huazi Xu, Yu Qian, Aimin Wu, Xiangyang Wang, Gang Zheng   +20 more
wiley   +1 more source

Brazing of Thin-Walled Stainless Steel Using Environmentally Friendly Ni-Cr-P Electrodeposition: Degradation Mechanism of Brazed Joint and Corresponding Improvement Strategy. [PDF]

Materials (Basel)
Liu S, Luan Y, Shohji I.
europepmc   +1 more source

THE OXIDATIVE DEGRADATION OF GLYCINE BY A PSEUDOMONAS

, 1955
L. Leon Campbell
openalex   +1 more source

Cardiomyocyte‐Enriched USP20 Ameliorates Pathological Cardiac Hypertrophy by Targeting STAT3 Deubiquitination

Advanced Science, EarlyView.
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong, Shanshan Dai, Fan Yu, Guo‐Ping Shi, Qinyan Gong, Yucong Zhang, Jingsi Duan, Zhengyin Lou, Zhixuan Tang, Fuzhe Gong, Derong Chen, Liya Hou, Xinyang Hu, Jinghai Chen, Jian'an Wang, Deling Yin   +15 more
wiley   +1 more source

Methionine, threonine and glutamic acid adapted pathways in captive cheetahs on a glycine-supplemented diet. [PDF]

Metabolomics
van Boom KM, Kohn TA, Tordiffe ASW.
europepmc   +1 more source

THE METABOLIC ACTIVITY OF THE α-, β-, AND γ-HYDROGEN ATOMS OF l-LEUCINE AND THE α-HYDROGEN OF GLYCINE

, 1950
David B. Sprinson, D. Rittenberg
openalex   +1 more source

Germicidal Efficiency of Chlorine and the N-chloro Derivatives of Ammonia, Methylamine and Glycine Against Anthrax Spores [PDF]

, 1930
F. W. Tilley, Robert M. Chapin
openalex   +1 more source

The Electric Mobilities of Glycine, Alanine, and Glycyl-glycine. [PDF]

Acta Chemica Scandinavica, 1949
Harry Svensson, Inger Brattsten, Allan Benjaminsson   +2 more
openaire   +2 more sources

Post‐Translational Modifications in Cilia and Ciliopathies

Advanced Science, EarlyView.
This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley   +1 more source

Theoretical and experimental investigation of hydration behavior of choline salicylate ionic liquid in the presence of L- glycine. [PDF]

Sci Rep
Ammari N, Shekaari H, Golmohammadi B, Ghaffari F, Zafarani-Moattar MT.   +4 more
europepmc   +1 more source