Results 231 to 240 of about 622,510 (345)

Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

Advanced Science, EarlyView.
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang, Qi Wang, Dongkun Kang, Shijia Wang, Yanli Jiang, Jian‐Zhi Wang, Chen Ming, Rong Liu, Jianlan Gu, Xiaochuan Wang   +9 more
wiley   +1 more source

Optimizing Cellular Metabolism Through Mass Balance Analysis to Improve Skin Wound Healing. [PDF]

Biology (Basel)
Agudelo LR, Yarmush G, Kumar S, Berthiaume F.   +3 more
europepmc   +1 more source

THE METABOLIC ACTIVITY OF THE α-, β-, AND γ-HYDROGEN ATOMS OF l-LEUCINE AND THE α-HYDROGEN OF GLYCINE

, 1950
David B. Sprinson, D. Rittenberg
openalex   +1 more source

IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

Advanced Science, EarlyView.
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu, Qing Lu, Zixuan Fan, Jiahui Lin, Nan He, Xin Zhang, Zhaoya Han, Tingting Zhu, Zhenzhen Wu, Yingying Xu, Yuming Wang   +10 more
wiley   +1 more source

Harnessing de-oiled <i>Glycine max</i> seed-anchored-CuO nanoparticles for adsorptive removal of crystal violet dye with comprehensive mechanistic insights. [PDF]

RSC Adv
Usman M, Batool F, Iqbal T, Noreen S, Gondal HY, Roheen T, Qadir R, Amin M, Sajid S, Ditta A.   +9 more
europepmc   +1 more source

Contribuição aos métodos de extermínio de ervas daninhas com herbicidas na cultura de soja (>i<Glycine max>/i< (L.) Merrill) em latosol vermelho amarelo fase arenosa [PDF]

, 1900
Luciano Souza Paes Cruz
openalex   +1 more source

Cathepsin K Aggravates Pulmonary Fibrosis Through Promoting Fibroblast Glutamine Metabolism and Collagen Synthesis

Advanced Science, EarlyView.
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen, Xiaoxiao Meng, Yong Zhu, Dapeng Wang, Mengmeng Wang, Ziyuan Wang, Xue Tian, Jiaxiang Zhang, Zhiying Yue, Zhengfeng Yang, Ruilan Wang   +10 more
wiley   +1 more source

How Osmolytes Regulate Protein-Ligand Interactions: The Case of α‑Chymotrypsin and Proflavine. [PDF]

JACS Au
Vieyto-Nuñez JC, Campanile M, Mieres-Perez J, Ostermeier L, Agar C, Petraccone L, Del Vecchio P, Oliva R, Winter R, Sanchez-Garcia E.   +9 more
europepmc   +1 more source

Human Bone‐Derived Endothelial Cells Mediate Bone Regeneration via Distinct Expression of KIT Ligand

Advanced Science, EarlyView.
Bone‐specific endothelial cells (b‐ECs) uniquely express KITLG, which recruits c‐Kit+/CD34+ hematopoietic progenitors (HPCs) to the osteovascular niche, initiating a cascade that culminates in the osteogenic differentiation of bone marrow‐derived mesenchymal stem cells (bm‐MSCs) and subsequent ossification.
Xiang Li, Hwan D. Kim, Allen C. Luo, Liyan Gong, Yonglin Zhu, Chin Nien Lee, Xuechong Hong, Christopher L. Sudduth, Michal Ad, Young‐Hyeon An, Mihn Jeong Park, Do‐Gyoon Kim, Arin K. Greene, Bonnie L. Padwa, Nathaniel S. Hwang, Ruei‐Zeng Lin, Juan M. Melero‐Martin   +16 more
wiley   +1 more source

Glycine betaine treatment extends the shelf life and retards cap browning of button mushrooms. [PDF]

Sci Rep
Malekzadeh P, Kamrani A, Abbasi Z, Sadeghi M.   +3 more
europepmc   +1 more source