Results 81 to 90 of about 614,810 (345)
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
Acta Agrobotanica, 2019 A nutrient solution experiment was performed using sand culture to evaluate the effects of different glycine levels on the growth and nutrient uptake of coriander (Coriandrum sativum L.).
Nikta Mohammadipour, M. Souri
semanticscholar +1 more source
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Synthesis and characterization of manganese-glycine and copper-glycine adducts [PDF]
Química Nova, 2002 This work reports the synthesis and characterization of adducts of general formula MCl2.ngly, where M= Mn and Cu; n= 2 and 4, and gly= glycine. The manganese adducts were synthesized by dissolution of both, manganese chloride and glycine in water, whereas the copper adducts were obtained by using an alternative solid state synthesis approach.
openaire +5 more sources
N‐Arachidonyl‐glycine inhibits the glycine transporter, GLYT2a [PDF]
Journal of Neurochemistry, 2006 AbstractN‐arachidonyl‐glycine is one of a series of N‐arachidonyl‐amino acids that are derived from arachidonic acid. N‐arachidonyl‐glycine is produced in a wide range of tissues with greatest abundance in the spinal cord. Here we report that N‐arachidonyl‐glycine is a reversible and non‐competitive inhibitor of glycine transport by GLYT2a, but has ...
Amy L. Wiles +4 more
openaire +3 more sources
Tuning the Flexibility of Glycine-Serine Linkers To Allow Rational Design of Multidomain Proteins
Biochemistry, 2017 Flexible polypeptide linkers composed of glycine and serine are important components of engineered multidomain proteins. We have previously shown that the conformational properties of Gly-Gly-Ser repeat linkers can be quantitatively understood by ...
M. van Rosmalen, Mike D. Krom, M. Merkx
semanticscholar +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
FEBS Open Bio, EarlyView.Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji +3 more
wiley +1 more source
Pharmaceutical Biology, 2017 Context: Nigella sativa L. (Ranunculaceae) (NS) has been used for medicinal and culinary purposes. Different parts of the plant are used to treat many disorders.
Tarek El-Naggar +3 more
doaj +1 more source
Unmasking GluN1/GluN3A excitatory glycine NMDA receptors
Nature Communications, 2018 GluN3A and GluN3B are glycine-binding subunits belonging to the NMDA receptor (NMDAR) family that can assemble with the GluN1 subunit to form unconventional receptors activated by glycine alone.
Teddy Grand +4 more
semanticscholar +1 more source