Results 61 to 70 of about 972,024 (289)

A Search for Propylene Oxide and Glycine in Sagittarius B2 (LMH) and Orion

, 2007
We have used the Mopra Telescope to search for glycine and the simple chiral molecule propylene oxide in the Sgr B2 (LMH) and Orion KL, in the 3-mm band.
B. Fulton, Bailey, C. Purcell, D. M. Cragg, I. Bains, J. Shobbrook, J. T. Dempsey, L. Kedziora-Chudczer, M. B. Pracy, M. G. Burton, M. G. Hidas, M. R. Cunningham, N. H. M. Crighton, P. A. Jones, P. Calisse, P. D. Godfrey, S. J. Curran, T. Hill, T. M. Davis, T. Travouillon, V. Minier, Zuwei   +21 more
core   +1 more source

C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins [PDF]

, 2014
An expanded GGGGCC repeat in C9orf72 is the most common genetic cause of frontotemporal dementia and amyotrophic lateral sclerosis. A fundamental question is whether toxicity is driven by the repeat RNA itself and/or by dipeptide repeat proteins ...
Cabecinha, M, Clayton, EL, Cleverley, K, Devoy, A, Dols, J, Fisher, EMC, Fratta, P, Grönke, S, Hendrich, O, Isaacs, AM, Mizielinska, S, Moens, T, Niccoli, T, Nicoll, AJ, Norona, FE, Partridge, L, Pickering-Brown, S, Pietrzyk, J, Ridler, CE, Woollacott, IOC   +19 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Feeding Preference Studies of Adult \u3ci\u3eNezara Viridula\u3c/i\u3e (Hemiptera: Pentatomidae) Morphs from India and the United States [PDF]

, 2017
Nezara viridula (Linnaeus) morphs from India and the United States were studied in a laboratory comparison of feeding preferences for pods of soybeans, Glycine max, and green beans, Phaseolus vulgaris. Adults of a morph from the U.S.
Armbrust, Edward J, DeWitt, Jerald R
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Detectability of Glycine in Solar-type System Precursors

, 2014
Glycine (NH2CH2COOH) is the simplest amino acid relevant for life. Its detection in the interstellar medium is key to understand the formation mechanisms of pre-biotic molecules and their subsequent delivery onto planetary systems.
Caselli, Paola, Jimenez-Serra, Izaskun, testi, Leonardo, Viti, Serena   +3 more
core   +1 more source

Effect of biofilm removal from the occlusal tooth surfaces on fluorescence measurements. A clinical study [PDF]

, 2018
Aim: Early diagnosis and monitoring of caries lesions are the most important issues of primary and secondary prevention policies.The intraoral VistaCamiX(DurrDental, Bietigheim‐Bissingen,Germany) uses the fluorescence phenomenon for a non‐invasive ...
Corridore, Denise, Guerra, Fabrizio, Mazur, Marta Danuta, Nardi, Gianna Maria, Ndokaj, Artnora, Ottolenghi, Livia, Pasqualotto, Debora, Rinaldo, Francesca, Salvi, Daniele   +8 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

QSAR Relationships The Changes in the Ratio of Electrons to the Natural Charge of Atoms in the Complexes of Glycine and Alanine Amino Acids with Intermediates [PDF]

International Journal of New Chemistry, 2017
In this paper, the quantum chemistry calculations related to the structural parameter of the three anions and the resulting complexes with glycine and alanine have been performed.
Hamideh Shahzad
doaj   +1 more source

Dietary protein reduction with stepwise addition of crystalline amino acids and the effect of considering a minimum glycine-serine content in broiler diets

Poultry Science, 2023
: Reducing the dependency on soybean meal (SBM) is necessary to improve the sustainability of the poultry industry. Moreover, the recommendations for minimum contents of dietary Gly+Ser require further research.
Wilfredo D. Mansilla, Saritha Saraswathy, Ana I. García-Ruiz   +2 more
doaj   +1 more source