Results 201 to 210 of about 398,460 (354)

Binding patterns of glycine receptor autoantibodies are related to clinical syndromes. [PDF]

Acta Neuropathol Commun
Piro I, Wiessler AL, Kakavela E, Baykan B, Tüzün E, Villmann C, Sommer C.   +6 more
europepmc   +1 more source

Glycine Receptor Subtypes and Their Roles in Nociception and Chronic Pain. [PDF]

Front Mol Neurosci, 2022
San Martín VP, Sazo A, Utreras E, Moraga-Cid G, Yévenes GE.   +4 more
europepmc   +1 more source

SUBUNIT SPECIFIC MODULATION OF GLYCINE RECEPTORS BY GINKGOLIC ACID [PDF]

, 2016
Galyna Maleeva, Svetlana Buldakova, Pìotr Bregestovski   +2 more
openalex   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

The glycine receptor alpha 3 subunit mRNA expression shows sex-dependent differences in the adult mouse brain. [PDF]

BMC Neurosci, 2023
Ceder MM, Weman HM, Johansson E, Henriksson K, Magnusson KA, Roman E, Lagerström MC.   +6 more
europepmc   +1 more source

Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N‐methyl‐D‐aspartate receptor.

, 1990
Graeme Henderson, John Johnson, Philippe Ascher   +2 more
openalex   +2 more sources

Glycine Betaine Recognition through Cation−π Interactions in Crystal Structures of Glycine Betaine Complexes with C-Ethyl-pyrogallol[4]arene and C-Ethyl-resorcin[4]arene as Receptors [PDF]

, 2013
Ikuhide Fujisawa, Katsuyuki Aoki
openalex   +1 more source

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti‐CEACAM5 CAR T‐Cell Efficacy Against Colorectal Cancer

Advanced Science, EarlyView.
This study shows anti‐CEACAM5 CAR T‐cells are ineffective against colorectal cancer (CRC) because of CEACAM5 sequestration at intercellular junctions and the thick tumour cell glycocalyx. Enzymatic treatments of CRC cell monolayer/tissue section with trypsin or hyaluronidase restore CEACAM5 availability, enhance CAR T‐cell activation, increase ...
Debasis Banik, Christopher J. Ward, Soura Chakraborty, Ziwei Zhang, Daniel Heraghty, Prasanna Suresh, Bing Li, Shekhar Kedia, Jhuma Pramanik, Simon J. Davis, James P. Roy, Michael A. Chapman, Bidesh Mahata, David Klenerman   +13 more
wiley   +1 more source

Molecular correlates of glycine receptor activity in human β cells. [PDF]

Mol Metab
Schukarucha Gomes A, Ellis CE, Spigelman AF, Dos Santos T, Maghera J, Suzuki K, MacDonald PE.   +6 more
europepmc   +1 more source

Lateral fenestrations in the extracellular domain of the glycine receptor contribute to the main chloride permeation pathway. [PDF]

Sci Adv, 2022
Cerdan AH, Peverini L, Changeux JP, Corringer PJ, Cecchini M.   +4 more
europepmc   +1 more source