Results 21 to 30 of about 394,690 (299)

Neuroprotection via Strychnine-Sensitive Glycine Receptors During Post-ischemic Recovery of Excitatory Synaptic Transmission in the Hippocampus

Journal of Pharmacological Sciences, 2010
Recent evidence indicates that strychnine-sensitive glycine receptors are located in upper brain regions including the hippocampus. Because of excitatory effects of glycine via facilitation of NMDA-receptor function, however, the net effects of increased
Mitsuo Tanabe, Azusa Nitta, Hideki Ono
doaj   +1 more source

New hyperekplexia mutations provide insight into glycine receptor assembly, trafficking, and activation mechanisms [PDF]

, 2013
Background: Hyperekplexia mutations have provided much information about glycine receptor structure and function. Results: Weidentified and characterized nine new mutations.
Alfred P. Born, Amanda Krause, Amira Masri, Angelo Keramidas, Anna Bode, Bakker, Beato, Bellini, Brune, Bulent Kara, Butler, Catherine Vincent-Delorme, Chen, Cheney J.G. Drew, Chung, Chung, Corringer, Davies, Elie G. Karam, Elizabeth A. Jones, Emma Hobson, Engel, Estrada-Mondragón, Eswar, Fusun Alehan, Gail E. Graham, Gerald Bannasch, Grace Vassallo, Graham, Grudzinska, Grünberg, Haeger, Hanna Mandel, Harvey, Hibbs, Humeny, Islam, James, Jean-François Vanbellinghen, Jonathan G.L. Mullins, Joseph W. Lynch, Jubran E. Rahme, Kang, Kling, Kruger, Langosch, Lynch, Lynch, Lynch, Marius Bartsch, Mark I. Rees, Michael Freilinger, Miraglia Del Giudice, Notredame, Owain W. Howell, Pettersen, Pless, Pless, Pless, Pons, Rajendra, Rea, Rees, Rees, Rees, Rhys H. Thomas, Ryan, Samuel F. Berkovic, Saul, Seo-Kyung Chung, Sharon Aharoni, Shiang, Shiang, Sian-Elin Wood, Simon, Stephanie Matta, Sue Chatfield, Thomas, Thomas, Thomas D. Cushion, Unterer, Vergouwe, Villmann, Villmann, Vivek Jain, Wang, Wheeler, William O. Pickrell, Yang, Zaid Afawi   +89 more
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Serotonin drives a novel GABAergic synaptic current recorded in rat cerebellar purkinje cells: a lugaro cell to purkinje cell synapse [PDF]

, 2003
We recorded a novel fast GABAergic synaptic current in cerebellar Purkinje cells in rat brain slices using patch-clamp techniques. Because of a relatively low sensitivity to bicuculline, these currents can be recorded under conditions in which basket and
Dean, I., Edwards, F.A., Robertson, S.J.
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Glycine is able to induce both a motility speed in- and decrease during zebrafish neuronal migration

Communicative & Integrative Biology, 2018
Various neurotransmitters influence neuronal migration in the developing zebrafish hindbrain. Migrating tegmental hindbrain nuclei neurons (THNs) are governed by depolarizing neurotransmitters (acetylcholine and glutamate), and glycine. In mature neurons,
Ulrike Theisen, Sven Hey, Christian D. Hennig, Ralf Schnabel, Reinhard W. Köster   +4 more
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Identifying functional populations among the interneurons in laminae I-III of the spinal dorsal horn [PDF]

, 2017
The spinal dorsal horn receives input from primary afferent axons, which terminate in a modality-specific fashion in different laminae. The incoming somatosensory information is processed through complex synaptic circuits involving excitatory and ...
Todd, Andrew J.
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4-Chloropropofol enhances chloride currents in human hyperekplexic and artificial mutated glycine receptors

BMC Neurology, 2012
Background The mammalian neurological disorder hereditary hyperekplexia can be attributed to various mutations of strychnine sensitive glycine receptors.
de la Roche Jeanne, Leuwer Martin, Krampfl Klaus, Haeseler Gertrud, Dengler Reinhard, Buchholz Vanessa, Ahrens Jörg   +6 more
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Different Sites of Alcohol Action in the NMDA Receptor GluN2A and GluN2B Subunits [PDF]

, 2015
The NMDA receptor is a major target of alcohol action in the CNS, and recent behavioral and cellular studies have pointed to the importance of the GluN2B subunit in alcohol action.
Allgaier, Alvestad, Anders, Anders, Boyce-Rustay, Chandrasekar, Chu, Dingledine, Donard S. Dwyer, Dopico, Dwyer, Erreger, Gass, Gonzales, Göthert, Hoffman, Holmes, Hong Ren, Honse, Izumi, Karakas, Kash, Kash, Kash, Koob, Krishnan-Sarin, Krupitsky, Krystal, Kuner, Lima-Landman, Lovinger, Low, Low, Masood, Mihic, Moykkynen, Nagy, Peoples, Peoples, Peoples, Popp, Ren, Ren, Ren, Ren, Ren, Ren, Robert W. Peoples, Ronald, Salous, Smothers, Smothers, Smothers, Sobolevsky, Sobolevsky, Vengeliene, Vengeliene, Wang, Weiss, Wick, Wills, Woodward, Woodward, Wright, Xu, Xu, Yamakura, Yuan, Yulin Zhao   +68 more
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A role for accumbal glycine receptors in modulation of dopamine release by the glycine transporter-1 inhibitor Org25935

Frontiers in Psychiatry, 2011
Accumbal glycine modulates basal and ethanol-induced dopamine levels in the nucleus accumbens (nAc) as well as voluntary ethanol consumption. Also, systemic administration of the glycine transporter-1 inhibitor Org25935 elevates dopamine levels in nAc ...
Helga eHöifödt Lidö, Mia eEricson, Hugh eMarston, Bo eSöderpalm, Bo eSöderpalm   +4 more
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Case report: Varicella-zoster virus infection triggering progressive encephalomyelitis with rigidity and myoclonus

Frontiers in Neurology, 2022
Progressive encephalomyelitis with rigidity and myoclonus (PERM) is a rare neurological disease of unknown etiology, and most patients with PERM are positive for anti-glycine receptor (GlyR) antibody.
Jing Yuan, Aihua Wang, Yunfeng Hou, Xuxu Xu   +3 more
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Neuronal circuitry for pain processing in the dorsal horn [PDF]

, 2010
Neurons in the spinal dorsal horn process sensory information, which is then transmitted to several brain regions, including those responsible for pain perception.
A Dhaka, A Ribeiro-da-Silva, A Ribeiro-da-Silva, AF Keller, AG Brown, AH Watson, AJ Todd, AJ Todd, AJ Todd, AJ Todd, AJ Todd, AJ Todd, AJ Todd, AJ Todd, AJ Todd, AJ Todd, AJ Todd, AL Bailey, AM Taylor, Andrew J. Todd, AR Light, AW Hantman, AW Hantman, B Lynn, B Rexed, BA Graham, C Albuquerque, C Gauriau, C Gauriau, C Gauriau, C Torsney, CJ Woodbury, CJ Woodbury, CJ Woolf, D Andrew, D Lima, D Lima, D Lima, D Lima, D Schoffnegger, D Schoffnegger, D Uta, DI Hughes, DI Hughes, DI Hughes, DJ Cavanaugh, DJ Maxwell, DL Bennett, DS Bredt, E Polgár, E Polgár, E Polgár, E Polgár, E Polgár, E Polgár, E Polgár, E Polgár, E Polgár, E Polgár, E Polgár, ET Zhang, ET Zhang, G Kato, GG Nagy, GJ Bennett, GJ Michael, GT Whiteside, H Baba, H Bester, H Ikeda, H Ikeda, H Sakamoto, HJ Hu, HY Huang, I Decosterd, I Laing, J Sandkuhler, J Scholz, J Zheng, JA Coull, JA Esteban, JF Bernard, JH Hwang, JJ Azkue, JL Hylden, JM Castro-Lopes, K Abe, K Feil, K Noguchi, KA Moore, KM Al-Khater, KM Al-Khater, KS Al Ghamdi, L Almarestani, L Sivilotti, LE Lorenzo, M Antal, M Antal, M Gassner, M Larsson, M Malcangio, M Mori, M Naim, M Okamoto, M Randic, M Rethelyi, M Zoli, MB Plenderleith, MJ Eaton, MJ Perry, MJ Zylka, ML Nichols, MM Heinricher, MM Naim, MW Salter, NK Littlewood, P Boscan, P Brumovsky, P Shortland, PD Wall, PW Mantyh, PW Mantyh, Q Liu, R Burstein, R Ruscheweyh, R Ruscheweyh, RC Spike, RC Spike, RM Slugg, RP Seal, RR Ji, S Neumann, S Neumann, SA Prescott, SA Shehab, SF Santos, SH Kim, SN Lawson, SP Schneider, T Ibuki, T Kemp, T Kohno, T Yasaka, T Yasaka, TJ Grudt, TL Yaksh, TP Malan, VS Seybold, WD Snider, WD Willis, X Zhang, X Zhang, XH Yu, Y Lu, Y Lu, Y Lu, YG Tong, YQ Ding, Z Puskár, ZS Han   +159 more
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