Results 31 to 40 of about 175,730 (291)
Zinc modulation of glycine receptors [PDF]
Neuroscience, 2011 Glycine receptors are widely expressed in the mammalian central nervous system, and previous studies have demonstrated that glycine receptors are modulated by endogenous zinc. Zinc is concentrated in synaptic vesicles in several brain regions but is particularly abundant in the hippocampus and olfactory bulb.
P Q, Trombley, L J, Blakemore, B J, Hill
openaire +3 more sources
Effects of NR1 splicing on NR1/NR3B-type excitatory glycine receptors
BMC Neuroscience, 2009 Background N-methyl-D-aspartate receptors (NMDARs) are the most complex of ionotropic glutamate receptors (iGluRs). Subunits of this subfamily assemble into heteromers, which – depending on the subunit combination – may display very different ...
Orth Angela +2 more
doaj +1 more source
Glycine receptors in GtoPdb v.2021.3 [PDF]
, 2021 The inhibitory glycine receptor (nomenclature as agreed by the NC-IUPHAR Subcommittee on Glycine Receptors) is a member of the Cys-loop superfamily of transmitter-gated ion channels that includes the zinc activated channels, GABA_{A}, nicotinic ...
Lynch, Joseph. W. +5 more
core +1 more source
BMC Neurology, 2012 Background The mammalian neurological disorder hereditary hyperekplexia can be attributed to various mutations of strychnine sensitive glycine receptors.
de la Roche Jeanne +6 more
doaj +1 more source
Frontiers in Psychiatry, 2011 Accumbal glycine modulates basal and ethanol-induced dopamine levels in the nucleus accumbens (nAc) as well as voluntary ethanol consumption. Also, systemic administration of the glycine transporter-1 inhibitor Org25935 elevates dopamine levels in nAc ...
Helga eHöifödt Lidö +4 more
doaj +1 more source
New Therapeutic Strategy for Amino Acid Medicine: Glycine Improves the Quality of Sleep
Journal of Pharmacological Sciences, 2012 Glycine is a non-essential amino acid that has indispensable roles in both excitatory and inhibitory neurotransmission via N-methyl-D-aspartate type glutamate receptors and glycine receptors, respectively.
Makoto Bannai, Nobuhiro Kawai
doaj +1 more source
Pharmacology Research & Perspectives, 2023 The NMDA subtype of glutamate receptor serves as an attractive drug target for the treatment of disorders evolving from hyper‐ or hypoglutamatergic conditions.
Seth C. Boehringer +4 more
doaj +1 more source
Taurine: A Maternally Derived Nutrient Linking Mother and Offspring
Metabolites, 2022 Mammals can obtain taurine from food and synthesize it from sulfur-containing amino acids. Mammalian fetuses and infants have little ability to synthesize taurine. Therefore, they are dependent on taurine given from mothers either via the placenta or via
Shiro Tochitani
doaj +1 more source
Glycine Release Is Upregulated by Metabotropic Glutamate Receptor 1 in Mouse Hippocampus
BiomedicinesBackground/Objectives: The neurotransmitter glycine is involved in several physiological and pathological conditions in the Central Nervous System. Different biological structures, including glycine receptors and transporters, are under study as targets ...
Luca Raiteri +3 more
doaj +1 more source
Frontiers in Systems Neuroscience, 2011 The flow of cortical information through the basal ganglia is a complex spatiotemporal pattern of increased and decreased firing. The striatum is the biggest input nucleus to the basal ganglia and the aim of this study was to assess the role of ...
Louise eAdermark +3 more
doaj +1 more source