Results 91 to 100 of about 24,850 (223)

Investigating the candidacy of LPS-based glycoconjugates to prevent invasive meningococcal disease : Immunology of glycoconjugates with high carbohydrate loading

, 2010
We investigated the immune responses of rabbits that were immunised with lipopolysaccharide (LPS)-based glycoconjugates by measuring the reactivity of the derived sera to a panel of selected wild-type and mutant strains of Neisseria meningitidis.
Cox, Andrew D., James C. Richards, Biolchi, Alessia, St. Michael, Frank, Richards, James C., Chantelle M. Cairns, Giuliani, Marzia M., Cairns, Chantelle M., Andrew D. Cox, Lacelle, Suzanne, Dhamodharan Neelamegan, Hoe, J. Claire, Marzia M. Giuliani, Suzanne Lacelle, E. Richard Moxon, Neelamegan, Dhamodharan, Frank St. Michael, Moxon, E. Richard, Alessia Biolchi, J. Claire Hoe   +19 more
core   +1 more source

Synthesis, characterization, in silico and in vitro studies of novel glycoconjugates as potential antibacterial, antifungal, and antileishmanial agents

Open Chemistry
In the present work, several new glycoconjugates (8a–e) were generated from glycopyranosyl-α-trichloroacetimidates (sugar-OTCA) as glycosyl donors and dimethyl-l-tartrate as an aglycone acceptor in good to excellent yields.
Khan Sher Wali, Nayab Saira, Umar Muhammad Naveed, Khan Momin, Iqbal Anila, Ahmad Nasir, Rashid Haroon ur, Shah Muhammad Ishaq Ali, Gulfam Naila, Zahoor Muhammad, Ullah Riaz, Ali Essam A.   +11 more
doaj   +1 more source

Expedient and Facile One-Pot Syntheses of Triazole-Linked Glycoconjugates under Microwave Irradiation

, 2012
Effective microwave assisted one-pot syntheses of triazole- O-glycoconjugates and triazolylglycosides involving sequential glycosylation and click chemistry are ...
Sarkar, Swarbhanu, Sen, Asish Kumar, Dutta, Samrat   +2 more
core   +1 more source

Synthetic glycoconjugates characterize the fine specificity of Brucella A and M monoclonal antibodies

, 2017
Synthetic oligosaccharide glycoconjugates representing A and M epitopes ofBrucellabacteria define the fine specificity of five monoclonal antibodies.
N. Vijaya Ganesh, Joanna M. Sadowska, David R. Bundle, Satadru Sekhar Mandal   +3 more
core   +1 more source

A Histochemical Approach to Correlative Light and Electron Microscopic Detection of Acidic Glycoconjugates by a Sensitized High Iron Diamine Method

, 1998
A sensitized high iron diamine method is among the reliable and useful histochemical means of detecting acidic glycoconjugates by light microscopy. Because the final reaction products obtained using this method are heavy metals, it can be applied to ...
Yoshifumi Hirabayashi, Kazuyori Yamada
core   +1 more source

Dendritic cell lectin-targeting sentinel-like unimolecular glycoconjugates to release an anti-HIV drug

, 2014
A series of cyclodextrin-based glycoconjugates, including glycoclusters and star glycopolymers, were synthesized via combination of CuAAC Huisgen coupling and copper-mediated living radical polymerization.
Becer, C. Remzi, Zhang, Qiang, Su, Lu, Collins, Jennifer, Mitchell, Daniel A., Haddleton, David M., Wallis, Russell, Chen, Guosong   +7 more
core   +1 more source

Relative Quantitation of Subclass-Specific Murine IgG Fc N‑Glycoforms by Multiple Reaction Monitoring

ACS Omega, 2020
Jing Han, Qingmei Liu, Xiaoyan Xu, Wenjun Qin, Yiqing Pan, Ruihuan Qin, Ran Zhao, Yong Gu, Jianxin Gu, Shifang Ren   +9 more
doaj   +1 more source

Nanoparticles as Delivery Systems for Antigenic Saccharides: From Conjugation Chemistry to Vaccine Design

Vaccines
Glycoconjugate vaccines have been effective in preventing numerous bacterial infectious diseases and have shown recent potential to treat cancers through active immunotherapy.
Marie-Jeanne Archambault, Laetitia Mwadi Tshibwabwa, Mélanie Côté-Cyr, Serge Moffet, Tze Chieh Shiao, Steve Bourgault   +5 more
doaj   +1 more source

Lectin microarray analysis of salivary gland glycoproteins from arboviral vector Aedes aegypti and malaria vector Anopheles stephensi

Journal of Vector Borne Diseases
Background & objectives: Salivary gland proteins but not glycoconjugates have been previously studied in mosquito vectors of human diseases. Glycoconjugates from salivary gland-derived proteins from human-feeding tick vectors can elicit hypersensitivity ...
Ranjan Ramasamy, Xi Chen, Jian Zhang, Kokila Sivabalakrishnan, Sivasingham Arthiyan, Sinnathamby N Surendran   +5 more
doaj   +1 more source

Does Altered Membrane Glycosylation Contribute to Neurodevelopmental Dysfunction in Autism Spectrum Disorder?

Membranes
Neuronal development relies on cell-surface glycoconjugates that function as complex bioinformational codes. Recently, altered glycosylation has emerged as a central mechanistic theme in the pathophysiology of autism spectrum disorder (ASD).
Vinicius J. S. Osterne, Messias V. Oliveira, Vanir R. Pinto-Junior, Francisco S. B. Mota, Benildo S. Cavada, Kyria S. Nascimento   +5 more
doaj   +1 more source