Results 141 to 150 of about 260,438 (309)

Tricky TRIC: A replication study using trophoblast retrieval and isolation from the cervix to study genetic birth defects

open access: yesPrenatal Diagnosis, Volume 42, Issue 13, Page 1612-1621, December 2022., 2022
Abstract Objective Noninvasive Prenatal Diagnosis has recently been introduced for a limited number of monogenetic disorders. However, the majority of DNA diagnostics still require fetal material obtained using an invasive test. Recently, a novel technique, TRIC (Trophoblast Retrieval and Isolation from the Cervix), has been described, which collects ...
Marie van Dijk   +8 more
wiley   +1 more source

Structural Characterization, Phenolic Acid Modification, and Antioxidant Activities of Polysaccharide From Mogroside Waste Liquid of Siraitia grosvenorii

open access: yesFood Frontiers, EarlyView.
ABSTRACT To improve the comprehensive utilization of Siraitia grosvenorii (Swingle) C. Jeffrey, a novel polysaccharide (SGP) was isolated from the mogroside waste liquid of S. grosvenorii. In addition, ferulic acid–SGP (FA‐SGP) and caffeic acid–SGP (CA‐SGP) were prepared by modifying SGP with phenolic acid.
Jiajing Duan   +6 more
wiley   +1 more source

Exploring the Molecular Pathways Underlying the Anti‐Diabetic Effects of Millets

open access: yesFood Safety and Health, EarlyView.
Millet consumption may modulate gluconeogenesis and glycolysis, enhance glucose transporter activity, increase leptin levels, inhibit the NF‐κB pathway, and mitigate oxidative and nitrosative stress. ABSTRACT Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemic conditions resulting from inadequate insulin production or ...
Akash Kumar   +5 more
wiley   +1 more source

Protein aggregation and neurodegenerative disease: Structural outlook for the novel therapeutics

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView., 2023
Abstract Before the controversial approval of humanized monoclonal antibody lecanemab, which binds to the soluble amyloid‐β protofibrils, all the treatments available earlier, for Alzheimer's disease (AD) were symptomatic. The researchers are still struggling to find a breakthrough in AD therapeutic medicine, which is partially attributable to lack in ...
Sharif Arar   +2 more
wiley   +1 more source

GLYCOGEN REDUCTION IN CHICK LIVER DURING PULLORUM DISEASE [PDF]

open access: bronze, 1958
J. A. Cameron   +2 more
openalex   +1 more source

Biofunctional Nanodot Arrays in Living Cells Uncover Synergistic Co‐Condensation of Wnt Signalodroplets

open access: yesSmall, Volume 18, Issue 50, December 15, 2022., 2022
High‐density arrays of biofunctionalized nanodots with diameters of 300 nm enable spatially controlled assembly of active Wnt signaling platforms in the plasma membrane. Massive parallelization at the single cell level uncovers receptor density‐dependent co‐condensation of cytosolic effector proteins, suggesting digitalized transmembrane signaling ...
Michael Philippi   +15 more
wiley   +1 more source

Emerging Technologies for Timely Point‐of‐Care Diagnostics of Skin Cancer

open access: yesGlobal Challenges, EarlyView.
With the global incidence of skin cancer on the rise and a persistent lack of rapid, noninvasive and sensitive point‐of‐care diagnostic platforms, current and emerging technologies are critically reviewed. Among these, the emerging Raman spectroscopy system is identified as a promising complementary to conventional costly and invasive methods, offering
Jarrod L. Thomas   +2 more
wiley   +1 more source

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