AAV-mediated transcription factor EB (TFEB) gene delivery ameliorates muscle pathology and function in the murine model of Pompe Disease [PDF]
Pompe disease (PD) is a metabolic myopathy due to acid alpha-glucosidase deficiency and characterized by extensive glycogen storage and impaired autophagy.
Alvino, Filomena Grazia+13 more
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Variations in dissolved oxygen levels are common in the Amazonian aquatic environments and the aquatic organisms that inhabit these environments developed a variety of adaptive responses to deal with such conditions.
José L. Vasconcelos-Lima+3 more
doaj +1 more source
Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated-skeletal muscle insulin resistance [PDF]
Obesity and saturated fatty acid (SFA) treatment are both associated with skeletal muscle insulin resistance (IR) and increased macrophage infiltration. However, the relative effects of SFA and unsaturated fatty acid (UFA)-activated macrophages on muscle
Aguirre+67 more
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The success of Limnoperna fortunei as an invasive species is related to its physiological plasticity that allows them to endure adverse environmental conditions.
Nelmara I.S. Cordeiro+7 more
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Effect of high and low glycaemic index recovery diets on intramuscular lipid oxidation during aerobic exercise [PDF]
Intramyocellular lipid (IMCL) and plasma NEFA are important skeletal muscle fuel sources. By raising blood insulin concentrations, carbohydrate ingestion inhibits lypolysis and reduces circulating NEFA.
Emma Stevenson+5 more
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Thiamethoxam causes histochemical changes in the liver of Aristichthys nobilis Rich., 1845 [PDF]
In the present study, we aimed to investigate the effects of the neonicotinoid insecticide thiamethoxam on the hepatic glycogen in bighead carp (Aristichthys nobilis Rich.).
STELA STOYANOVA+4 more
doaj
Glycogen Metabolism and Its Role in Growth and Encystation in Entamoeba histolytica
Entamoeba histolytica is a parasitic protozoan that causes diarrheal disease in approximately 100 million people worldwide every year. E. histolytica has two forms, the growing trophozoite and the infectious cyst.
Jordan Wesel, Cheryl Ingram-Smith
doaj +1 more source
Pre-implantation mouse embryos cultured In vitro under different oxygen concentrations show altered ultrastructures [PDF]
Assisted Reproductive Technologies routinely utilize different culture media and oxygen (O2) concentrations to culture human embryos. Overall, embryos cultured under physiological O2 tension (5%) have improved development compared to embryos cultured ...
Antonouli, S+6 more
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Effects of Handling Processes on the Quality and Biochemical Changes in Tissue of Mud Crab, (Scylla serrata, Forsskål, 1755) During Emersion Storage [PDF]
The effects of handling processes were investigated in the mud crab, Scylla serrata, using pre-cooling and chelae tying during emersion storage.Muscle glycogen, muscle lactate, muscle yield, muscle pH, volatile basic nitrogen (VBN), and chemical ...
Waritchon Ninlanon
doaj
Glycogen availability can influence glucose transporter 4 (GLUT4) expression in skeletal muscle through unknown mechanisms. The multisubstrate enzyme AMP-activated protein kinase (AMPK) has also been shown to play an important role in the regulation of ...
Chan, Stanley+7 more
core +1 more source