Results 41 to 50 of about 345,366 (342)

Muscle glycogen remodeling and glycogen phosphate metabolism following exhaustive exercise of wild type and laforin knockout mice [PDF]

open access: yes, 2015
Glycogen, the repository of glucose in many cell types, contains small amounts of covalent phosphate, of uncertain function and poorly understood metabolism.
DePaoli-Roach, Anna A.   +5 more
core   +1 more source

Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity. [PDF]

open access: yes, 2014
Glycogen and lipids are major storage forms of energy that are tightly regulated by hormones and metabolic signals. We demonstrate that feeding mice a high-fat diet (HFD) increases hepatic glycogen due to increased expression of the glycogenic ...
Bridges, Dave   +12 more
core   +2 more sources

An investigation of acute effects at various doses of malathion on glucose homeostasis and insulin resistance in rat liver, pancreas and serum [PDF]

open access: yes, 2020
Objective. This study investigates acute effects of various doses of Malathion on glucose homeostasis and insulin resistance in rat. Methods. Rats were randomly divided into four groups of 6 animals each. Corn oil was given orally to Group 1.
Ekremoğlu, Murat   +4 more
core   +3 more sources

Glycogen autophagy

open access: yesMicroscopy Research and Technique, 2004
AbstractGlycogen autophagy, which includes the sequestration and degradation of cell glycogen in the autophagic vacuoles, is a selective process under conditions of demand for the massive hepatic production of glucose, as in the postnatal period. It represents a link between autophagy and glycogen metabolism. The formation of autophagic vacuoles in the
Kotoulas, O. B.   +2 more
openaire   +3 more sources

Insulin induces a positive relationship between the rates of ATP and glycogen changes in isolated rat liver in presence of glucose; a 31P and 13C NMR study

open access: yesNutrition & Metabolism, 2005
Background There is an emerging theory suggesting that insulin, which is known to be the predominant postprandial anabolic hormone, is also a major regulator of mitochondrial oxidative phosphorylation in human skeletal muscle.
Gin Henri   +4 more
doaj   +1 more source

GLYCOGEN FRACTIONS AND THEIR ROLE IN THE HISTOCHEMICAL DETECTION OF GLYCOGEN [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 1960
Glycogen fractions have been investigated in guinea pig liver by the anthrone technique and histochemically by Gomori's hexamine silver method. It is concluded that it is only the trichloroacetic acid soluble fraction of tissue glycogen that is demonstrated by this histochemical technique.
J. H. Kugler, W. J. C. Wilkinson
openaire   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Short and long-term acceptability and efficacy of extended-release cornstarch in the hepatic glycogen storage diseases: results from the Glyde study

open access: yesOrphanet Journal of Rare Diseases
Background Hypoglycaemia is the primary manifestation of all the hepatic types of glycogen storage disease (GSD). In 2008, Glycosade®, an extended-release waxy maize cornstarch, was reported as an alternative to uncooked cornstarch (UCCS) which could ...
DA Weinstein   +17 more
doaj   +1 more source

Anti-Fatigue Activity of Aqueous Extracts of Sonchus arvensis L. in Exercise Trained Mice

open access: yesMolecules, 2019
Sonchus arvensis L. is a nutritious vegetable and herbal medicine that is consumed worldwide. The aim of this study was to evaluate the anti-fatigue effects and underlying effects of aqueous extract of Sonchus arvensis L. (SA).
Tian Yuan   +9 more
doaj   +1 more source

Molar mass and solution conformation of branched alpha(1 - 4), alpha(1 - 6) Glucans. Part I: Glycogens in water [PDF]

open access: yes, 2008
Solution molar masses and conformations of glycogens from different sources (rabbit, oyster, mussel and bovine) were analysed using sedimentation velocity in the analytical ultracentrifuge, size-exclusion chromatography coupled to multi-angle laser light
Ang, S.   +6 more
core   +1 more source

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