Results 51 to 60 of about 260,438 (309)
Postprandial Glycogen Content Is Increased in the Hepatocytes of Human and Rat Cirrhotic Liver
Cells, 2021 Chronic hepatitises of various etiologies are widespread liver diseases in humans. Their final stage, liver cirrhosis (LC), is considered to be one of the main causes of hepatocellular carcinoma (HCC). About 80–90% of all HCC cases develop in LC patients,
Natalia N. Bezborodkina +2 more
doaj +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
Insects, 2021 Natural and anthropogenic changes have been altering many environmental factors. These include the amount of solar radiation reaching the Earth’s surface. However, the effects of solar radiation on insect physiology have received little attention.
Chunchun Li +6 more
doaj +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Glia, Volume 71, Issue 2, Page 229-244, February 2023., 2023 Main Points Gray and white matter astrocytes have different basal NADH/NAD+ redox states and ATP levels. Metabolism of both cell populations responds similarly to neuronal activity. Glutamate induced ATP loss is prevented by increasing extracellular K+.
Susanne Köhler +5 more
wiley +1 more source
Fat body glycogen serves as a metabolic safeguard for the maintenance of sugar levels in Drosophila
Development, 2018 Adapting to changes in food availability is a central challenge for survival. Glucose is an important resource for energy production, and therefore many organisms synthesize and retain sugar storage molecules.
Takayuki Yamada +3 more
semanticscholar +1 more source
Influence of post-mortem muscle glycogen content on the quality of beef during aging
Journal of Veterinary Research, 2016 Introduction: Glycolic changes which occur post-mortem have an impact on the physical and sensory features of beef, which in turn determine the successive processes and influence such beef quality traits as colour, tenderness, and cooling loss.
Onopiuk Anna +2 more
doaj +1 more source
Physiological Reports, 2023 This study aimed to determine effects of cooling on contraction‐induced peroxisome proliferator‐activated receptor γ coactivator‐1α (PGC‐1α) and vascular endothelial growth factor (VEGF) gene expression, phosphorylations of its related protein kinases ...
Daisuke Hoshino +7 more
doaj +1 more source
International Journal of Translational Medicine, 2021 Glycogen is present in all tissues, but it is primarily stored in the liver and in muscle. As a branched chain carbohydrate, it is broken down by phosphorylase and debrancher enzymes, which are cytoplasmic.
Allen K. Murray
doaj +1 more source
FEBS Open Bio, EarlyView.By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya +3 more
wiley +1 more source