Results 151 to 160 of about 130,693 (343)

Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology

Clinical Endocrinology, EarlyView.
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth, Thomas J. O'Leary, Craig L. Doig, Natalie Taylor, Jasminder Dosanjh, David R. Woods, Michael J. Stacey, Robert M. Gifford   +7 more
wiley   +1 more source

Inositol and Berberine Synergistically Reprogram Endocrine and Ovarian Metabolism in Polycystic Ovary Syndrome

Cell Proliferation, EarlyView.
In a DHEA+HFD‐induced mouse model, Ins/BBR alleviated mitochondrial defects and broadly reprogrammed metabolic landscape in granulosa cells, in specific, restoring nucleotide pools and amino acid turnover, and preventing abnormal long‐chain fatty acid accumulation.
Juan Ge, Chenxiang Zhang, Yilong Zhao, Haiyang Zhao, Shuai Zhu, Tao Tang, Guorui Zhang, Qiang Wang, Hui Wang   +8 more
wiley   +1 more source

McArdle’s Disease (Glycogen Storage Disease type V): A Clinical Case

, 2018
McArdle’s Disease, or Glycogen Storage Disease Type V, is the result of a deficiency in one of the enzymes responsible for the metabolism of glycogen in the body.
Cameselle-Arias M, Turienzo-Pacho F, Cameselle-Teijeiro JF*, Villar-Fernández B, Ruibal-Azevedo J, Charro Gamallo ME, Calheiros-Cruz T, Cameselle-Cortizo L, Caamaño-Vara MP, Yera Acosta A   +9 more
core   +1 more source

SCD2 Alleviates Diabetes‐Associated Cognitive Dysfunction by Improving Microglial Lipid Metabolism

Cell Proliferation, EarlyView.
This study reveals a novel mechanism of microglial metabolic dysfunction in diabetic cognitive impairment. Defective SCD2 disrupts monounsaturated fatty acid (MUFA) metabolism, triggering mitochondrial oxidative phosphorylation dysfunction and leading to abnormal lipid droplet accumulation (marked by PLIN2).
Yang Yang, Juan He, Jing Zheng, Bing Shao, Lixin Shi, Miao Zhang   +5 more
wiley   +1 more source

Placental Involvement in Glycogen Storage Disease Type IV

, 2008
Glycogen storage disease type IV (GSD IV) is a rare autosomal recessive disorder caused by glycogen branching enzyme (GBE) deficiency and resulting in the storage of abnormal glycogen (polyglucosan).
Dertinger, S., DiMauro, S., Konstantinidou, A.E., Patsouris, E., Nonni, A., Petersen, M., Marinos, E., Anninos, H., Akman, H.O., Havaki, S., Karadimas, C.   +10 more
core  

Bone marrow transplantation in glycogen storage disease type 1b.

, 2008
We report a case of glycogen storage disease type 1b that was successfully treated with bone marrow transplantation after life-threatening complications related to neutropenia and thrombocytopenia.
Chakupurakal, Geothy, Hendriksz, C, Pierre, G, Chakrapani, A, Lawson, Sarah, McKiernan, Patrick   +5 more
core   +1 more source

Aerobic Exercise Training Increases Circulating sRAGE in Adults With Type 2 Diabetes: Associations With Sheddase Regulation

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Objective Soluble receptor for advanced glycation end‐products (sRAGE) and soluble Toll‐like receptor 4 (sTLR4) are circulating pattern recognition receptor isoforms implicated in inflammatory regulation in type 2 diabetes mellitus (T2DM). This study examined the effects of supervised aerobic exercise training (AET) on circulating sRAGE, sTLR4,
Ryan K. Perkins, Corey E. Mazo, James Shadiow, Pallavi Varshney, Edwin R. Miranda, Victoria R. Miranda, Maggie Eisenberg, Jane E. Nakamura, Elif A. Oral, Jacob M. Haus   +9 more
wiley   +1 more source

The glycogen storage diseases [PDF]

Journal of Clinical Pathology, 1974
openaire   +3 more sources

Renal complications in glycogen storage disease type I

, 1993
Deficiency of the enzyme glucose-6-phosphatase is the biochemical defect in glycogen storage disease type I (GSD I). Normally this enzyme is present in the liver, intestine and kidneys.
Reitsma-Bierens, W.C.C., REITSMABIERENS, WCC   +1 more
core   +1 more source

Metabarcoding of Pollen Carried by Syrphids Reveals Novel Plant–Pollinator Interactions in a Protected Natural Area and Agricultural Sites

Entomologia Experimentalis et Applicata, EarlyView.
Using DNA metabarcoding, this study investigates pollen transported by syrphids (Syrphidae) in the Dolomiti Bellunesi National Park and agricultural sites in Northern Italy. The analysis reveals a high diversity of visited plant taxa, including previously undocumented plant–pollinator interactions.
Serena Magagnoli, Daniele Sommaggio, Claudio Ratti, Riccardo Baroncelli, Andrea Menicucci, Enrico Vettorazzo, Giovanni Burgio   +6 more
wiley   +1 more source