Results 171 to 180 of about 130,693 (343)

NAA10 and BTRC drive CREBRF degradation in endoplasmic reticulum stress and renal tubular injury

Journal of Diabetes Investigation, EarlyView.
In diabetic kidney disease (DKD), the acetyltransferase NAA10 mediates the acetylation of CREBRF, promoting its recognition and binding by the E3 ubiquitin ligase BTRC, thereby enhancing the ubiquitination level of CREBRF and accelerating its degradation.
Sitian Fang, Jing Ning, Jinjing Huang, Yanxia Chen   +3 more
wiley   +1 more source

Clinical study of respiratory function in patients with late-onset glycogen storage disease typeⅡ

Chinese Journal of Contemporary Neurology and Neurosurgery, 2014
Background Late-onset glycogen storage disease typeⅡ(GSDⅡ, Pompe disease) is an autosomal recessive disease exhibiting progressive proximal skeletal muscle weakness and respiratory muscle involvement, caused by deficiency of the lysosomal enzyme acid ...
Wei-na JIN, Cheng-li QUE, Hai-yan TANG, Yu HUANG, Zhao-xia WANG, Xiao LIU, He LÜ, Wei ZHANG, Yun YUAN   +8 more
doaj  

Next‐generation glycogen storage diseases [PDF]

Journal of Inherited Metabolic Disease, 2018
Derks, Terry G. J., Oosterveer, Maaike H., De Souza, Carolina F.   +2 more
openaire   +3 more sources

Chronic thermal stress affects growth, liver morphology and molecular responses but allows recovery at optimal temperature in juvenile zebrafish (Danio rerio)

Journal of Fish Biology, EarlyView.
Abstract Climate‐driven aquatic heatwaves pose an increasing threat to fish populations by inducing prolonged thermal stress. However, the resilience of teleosts to chronic heat exposure and their capacity for recovery remains poorly understood. This study investigated the effects of chronic high‐temperature exposure on juvenile zebrafish (Danio rerio).
Monique Adzijovski, Aaron G. Schultz, Jemma Bergfeld, Luis O. B. Afonso   +3 more
wiley   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Increased p‐Tau181 Levels After Overnight Wakefulness Are Associated With Neuroticism in Young Women

Journal of Sleep Research, EarlyView.
Overnight wakefulness, mimicking night shift conditions, impaired morning vigilance in healthy, reproductive‐aged women, regardless of estradiol or neuroticism. However, the overnight wakefulness‐related rise in the Alzheimer's disease blood biomarker p‐Tau181 was greater in women with higher neuroticism, suggesting that neurobiological vulnerability ...
Diana A. Nôga, Elisa M. S. Meth, Abdullah Almajni, Viviana Rossi, Camilla Zetterlund, Samira F. M. Noory, Michaela Danek, Asma Al‐Grety, André P. Pacheco, Meina Wu, Mia Phillipson, Henrik Zetterberg, Kim Kultima, Pei Xue, Christian Benedict   +14 more
wiley   +1 more source

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

Obesity Reviews, EarlyView.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad   +4 more
wiley   +1 more source

Insight into "Consensus recommendations for diagnosis and treatment of glycogen storage disease typeⅡ"

Chinese Journal of Contemporary Neurology and Neurosurgery, 2014
Glycogen storage disease typeⅡ (GSDⅡ) is a rare progressive lysosomal storage disease caused by deficiency of acid α-glucosidase (GAA). The gene is located in 17q25.3. Diagnosis has been classically made by means of muscular biopsy.
Hong-zhi GUAN, Li-ying CUI
doaj  

Nursing care about child with glycogen storage disease I. type

, 2018
Present Situation: Research investigation deals with nursing care of the child with glycogen storage disease type I., as well as its diagnosis, nutritional management and complications.
ŠŤASTNÍKOVÁ, Hana
core  

Effects of Glucagon‐Like Peptide‐1 Receptor Agonists (Mono and Combination Therapy) on Energy Expenditure: A Scoping Review

Obesity Reviews, EarlyView.
ABSTRACT Introduction Weight loss results in reduced energy expenditure (EE) due to body composition alterations (e.g., fat‐free mass and fat mass losses) and mass‐independent adaptations in EE (e.g., hormones). Glucagon‐like peptide‐1 receptor agonists (GLP‐1RA) are indicated for obesity management; however, their effects on EE remain unclear ...
Flavio T. Vieira, ZhiDi Deng, Manfred J. Muller, Giovanna G. L. Bergamasco, Sarah Cawsey, Melania Manco, Steven B. Heymsfield, Carla M. Prado, Andrea M. Haqq   +8 more
wiley   +1 more source