Results 121 to 130 of about 67,076 (344)

Ubiquitination in cancer: mechanisms and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu, Xu Zhang, Waner Liu, Zhe Zhou, Siyu Xiong, Jie Li, Xiang Chen, Cong Peng   +7 more
wiley   +1 more source

831 LONG TERM TREATMENT OF GLYCOGEN STORAGE DISEASE TYPE I (GSD I): CLINICAL IMPROVEMENT BUT PERSISTENT ABNORMALITIES OF LACTATE & TRIGLYCERIDE CONCENTRATION [PDF]

, 1978
Lester Baker, James L. Mills, Charles A. Stanley   +2 more
openalex   +1 more source

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

A case study of a liver transplant-treated patient with glycogen storage disease type Ia presenting with multiple inflammatory hepatic adenomas: an analysis of clinicopathologic and genetic data

BMC Medical Genomics
Background Glycogen storage disease (GSD) is a disease caused by excessive deposition of glycogen in tissues due to genetic disorders in glycogen metabolism.
Ao Wang, Jiamei Wu, Xiaohui Yuan, Jianping Liu, Changli Lu   +4 more
doaj   +1 more source

Uric Acid Metabolism in Therapy of Glycogen Storage Disease Type I [PDF]

, 1978
Paul J. Benke, Scott Gold
openalex   +1 more source

Development of Novel Anticancer Pyrazolopyrimidinones Targeting Glioblastoma

ChemMedChem, EarlyView.
Pyrazolo[1,5‐α]pyrimidinone derivatives exhibit selective cytotoxicity towards glioblastoma (GBM) cells over noncancerous cells. Structure–activity relationship studies identifies a lead compound with significant cytotoxicity activity, inducing apoptosis and necrosis in GBM cells, without affecting noncancerous cells. This demonstrates the potential of
Kate Byrne, Natalia Bednarz, Ciara McEvoy, John C. Stephens, James F. Curtin, Gemma K. Kinsella   +5 more
wiley   +1 more source

Continuous glucose monitoring in children with glycogenosis

Alʹmanah Kliničeskoj Mediciny, 2017
Rationale: Glycogen storage diseases (GSD, glycogenosis) are a group of hereditary disorders of carbohydrate metabolism that is characterized by excess glycogen accumulation in various organs and tissues due to deficiency or absence of glycogen-splitting
T. V. Strokova, I. V. Prokhorova, A. G. Surkov, M. E. Bagaeva, E. V. Pavlovskaya, N. N. Taran, A. I. Zubovich   +6 more
doaj   +1 more source

NEONATAL INTERVENTION IN TYPE I GLYCOGEN STORAGE DISEASE (GSD) [PDF]

, 1977
S L Maby, Marilyn L. Cowger, Lauren E. Howard, Joel J. White, H Lawrence Vallet   +4 more
openalex   +1 more source

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source

Intragastric Feeding in Type I Glycogen Storage Disease: Factors Affecting the Control of Lactic Acidemia [PDF]

, 1981
Charles A. Stanley, James L. Mills, Lester Baker   +2 more
openalex   +1 more source