Results 221 to 230 of about 67,076 (344)

Physical exercise intervention in glycogen storage disease IIIa: Feasibility and multisystem benefits

Experimental Physiology, EarlyView.
Abstract Glycogen storage disease III (GSD‐III) is caused by an inherited deficiency of the glycogen debranching enzyme. Affecting the liver, muscle and heart, GSD‐IIIa is the most common GSD‐III subtype. We evaluated the feasibility and safety of a physical exercise intervention in patients with GSD‐IIIa and its effects at the multisystem level.
Asunción Bustos‐Sellers, Almudena Montalvo‐Pérez, Araceli Boraita, Gonzalo Saco‐Ledo, Lidia B. Alejo, David Barranco‐Gil, Pedro L. Valenzuela, Nerea López‐Maldonado, Roser Ferrer‐Costa, Javier Esparcia‐Estrela, Celia Monteagudo‐López, Tomàs Pinós, Alejando Santos‐Lozano, Alejandro Lucia, Alfredo Santalla   +14 more
wiley   +1 more source

Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK [PDF]

, 2017
Austin, Christopher P., Dai, Sheng, Dulcey, Andres E., Hu, Xin, Marugan, Juan, Ory, Daniel S., Porter, Forbes D., Wassif, Christopher A., Zheng, Wei   +8 more
core   +2 more sources

The effects of short‐term consumption of a Western diet on aerobic exercise performance in bank voles with inherently distinct metabolic rates

Experimental Physiology, EarlyView.
Abstract Because obesity and related diseases are partly attributed to unrestricted consumption of a high‐fat, high‐sugar Western diet (WD), several studies have examined its adverse effects on health and physical fitness. However, short‐term WD supplementation has received little attention. We asked whether such supplementation can improve the aerobic
Alaa Hseiky, Edyta T. Sadowska, Paweł Koteja   +2 more
wiley   +1 more source

The contribution of transplantation to gastroenterologic knowledge [PDF]

, 1994
Starzl, TE
core  

Effects of short‐term exercise on plasma metabolic and lipidomic profiles of individuals with type 2 diabetes

Experimental Physiology, EarlyView.
Abstract Type 2 diabetes mellitus (T2DM) is a common metabolic disorder characterized by chronic hyperglycaemia, with physical inactivity and excessive adiposity as predisposing factors. This clinical trial aimed to investigate the effects of an exercise intervention on the metabolome of T2DM participants, fasting and in response to an oral glucose ...
Maartje Cox, Aaron Raman, Timothy Fairchild, John P. Beilby, Bu B. Yeap, Jeremy K. Nicholson, Julien Wist, Jeremiah Peiffer, Nathan G. Lawler   +8 more
wiley   +1 more source

Advances in <i>in vivo</i> magnetic resonance spectroscopy for metabolic disorders. [PDF]

Front Endocrinol (Lausanne)
Kupriyanova Y, Schrauwen-Hinderling V.
europepmc   +1 more source

Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle

Experimental Physiology, EarlyView.
Abstract MicroRNAs (miRNAs) are key regulators of cellular processes, including mitochondrial function and energy metabolism. This study explores the regulation of miR‐494 in skeletal muscle and circulation, investigating its response to exercise training and an acute exercise bout, its association with metabolic disorders, and the effects of ...
Natália Pálešová, Klára Gabrišová, Jana Babulicová, Patrik Krumpolec, Zuzana Kovaničová, Tímea Kurdiová, Salvatore Modica, Christian Wolfrum, Jozef Ukropec, Barbara Ukropcová, Miroslav Baláž   +10 more
wiley   +1 more source

An uncommon case of neonatal asphyxia associated with infantile-onset Pompe disease. [PDF]

Ital J Pediatr
Leo F, Barchi L, Russo G, Balestri E, Chesi E, Di Dio F, Garavelli L, Iughetti L, Gargano G.   +8 more
europepmc   +1 more source

Biogenesis and reformation of synaptic vesicles

The Journal of Physiology, EarlyView.
Abstract figure legend Synaptic vesicle proteins are axonally transported in precursor vesicles (PVs) before conversion into mature synaptic vesicles (SVs) that are reformed by local recycling at synapses. Abstract Communication within the nervous system relies on the calcium‐triggered release of neurotransmitter molecules by exocytosis of synaptic ...
Svenja Bolz, Volker Haucke
wiley   +1 more source

Ultrastructure of astrocytes using volume electron microscopy: A scoping review

The Journal of Physiology, EarlyView.
Abstract figure legend A complete overview on astrocyte ultrastructure with volume electron microscopy. The morphology of astrocytes under physiological and pathological conditions plays a role in brain homeostasis, synaptic activity and structural support, but their morphological complexity and heterogeneity are still poorly quantified.
Vanessa Chiappini, Maria Fernanda Veloz Castillo, Francesco Biancardi, Ferdinando Di Cunto, Pierre J. Magistretti, Alessandro Vercelli, Marco Agus, Corrado Calì   +7 more
wiley   +1 more source