Results 91 to 100 of about 147,796 (254)

Activation of Glycogen Synthase by Insulin in 3T3-L1 Adipocytes Involves c-Cbl-associating Protein (CAP)-dependent and CAP-independent Signaling Pathways [PDF]

, 2001
Christian A. Baumann, Matthew Brady, Alan R. Saltiel   +2 more
openalex   +1 more source

Design, synthesis, and biological evaluation of chalcones for anticancer properties targeting glycogen synthase kinase 3 beta [PDF]

, 2022
Seunghyun Ahn, Vi Nguyen-Phuong Truong, Beomsoo Kim, Miri Yoo, Yoongho Lim, Somi Kim Cho, Dongsoo Koh   +6 more
openalex   +1 more source

Different effects of glucagon and epinephrine on the kinetic properties of liver glycogen synthase [PDF]

, 1983
Fátima Bosch, Carlos J. Ciudad, Joan J. Guinovart   +2 more
openalex   +1 more source

Glycogen synthase kinase 3 controls T-cell exhaustion by regulating NFAT activation [PDF]

, 2023
Yubing Fu, Jinjia Wang, Chenfeng Liu, Kunyu Liao, Xianjun Gao, Ronghan Tang, Fan Binbin, Yazhen Hong, Nengming Xiao, Changchun Xiao, Wen‐Hsien Liu   +10 more
openalex   +1 more source

Glycogen is a neutral cargo of bulk autophagy in Komagataella phaffii

Autophagy Reports
Glycogen is a primary cellular energy store in numerous eukaryotes. Its biosynthesis is a main strategy to cope with forthcoming starvation. During starvation, glycogen is processed in the cytosol or delivered for degradation to animal lysosomes or yeast
Nimna V. Wijewantha, Taras Y. Nazarko
doaj   +1 more source

GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animals

Neurobiology of Disease, 2009
The dysregulation of glycogen synthase kinase-3 (GSK3) has been implicated in Alzheimer disease (AD) pathogenesis and in Aβ-induced neurotoxicity, leading us to investigate it as a therapeutic target in an intracerebroventricular Aβ infusion model ...
Shuxin Hu, Aynun N. Begum, Mychica R. Jones, Mike S. Oh, Walter K. Beech, Beverly Hudspeth Beech, Fusheng Yang, Pingping Chen, Oliver J. Ubeda, Peter C. Kim, Peter Davies, Qiulan Ma, Greg M. Cole, Sally A. Frautschy   +13 more
doaj   +1 more source

The Akt-Glycogen Synthase Kinase 3β Pathway Regulates Transcription of Atrial Natriuretic Factor Induced by β-Adrenergic Receptor Stimulation in Cardiac Myocytes [PDF]

, 2000
Carmine Morisco, David C. Zebrowski, Gianluigi Condorelli, Philip N. Tsichlis, Stephen F. Vatner, Junichi Sadoshima   +5 more
openalex   +1 more source

Elevated glycogen synthase kinase 3 activity in Fragile X mice: key metabolic regulator with evidence for treatment potential [PDF]

, 2007
Significant advances have been made in understanding the underlying defects of and developing potential treatments for Fragile X Syndrome (FXS), the most common heritable mental retardation.
Bauchwitz, Dr. Robert P.
core  

Research advances of glycogen synthetic kinase-3β in diabetic nephropathy

Linchuang shenzangbing zazhi, 2021
The pathogenesis of diabetic kidney disease（DKD）is rather complicated.And glycogen synthase-3 plays important roles in many signaling pathways in body.For chronic kidney injury caused by diabetes, it is involved in the damage process of glomerular ...
He Zhi-xiu, Ma Chan-juan
doaj  

Local anaesthetic bupivacaine induced ovarian and prostate cancer apoptotic cell death and underlying mechanisms in vitro

, 2016
Retrospective studies indicate that the use of regional anesthesia can reduce cancer recurrence after surgery which could be due to ranging from immune function preservation to direct molecular mechanisms.
Chen, L, Hankin, J, Ma, D, Xuan, W, Yao, S, Zhao, H   +5 more
core   +3 more sources