Results 161 to 170 of about 454,859 (358)
GLYCOGEN SYNTHASE DEFICIENCY: METABOLIC AND TISSUE STUDIES [PDF]
Rosalind S. Brown+2 more
openalex +1 more source
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai+9 more
wiley +1 more source
Glycogen synthase kinase 3β: a key player in progressive chronic kidney disease. [PDF]
Zhang M, Tatar M, Gong R.
europepmc +1 more source
Upregulation of ST3GAL5 predicts suppression of malignant biological behavior in bladder cancer
Abstract Background Bladder cancer (BLCA) is the most prevalent malignancy in the urinary tract system, while ST3GAL5 is a protein‐coding gene that catalyzes the formation of ganglioside monosialodihexosylganglioside 3 (GM3) synthase. GM3 synthase has been reported to significantly influence the malignant process of various cancers.
Song Ou‐Yang+3 more
wiley +1 more source
Mitogen inactivation of glycogen synthase kinase-3β in intact cells via serine 9 phosphorylation [PDF]
Vuk Stambolic, James R. Woodgett
openalex +1 more source
Nuclear glycogen synthase — an artifact of preparation
Joseph Larner+2 more
openaire +3 more sources
Abstract Background and objectives Epididymal transit renders key competence to mammalian spermatozoa for fertilizing eggs. Generally, the two paralogs of glycogen synthase kinase 3, GSK3α and GSK3β, functionally overlap except in testis and sperm. We showed that GSK3α is essential for epididymal sperm maturation and fertilization.
Mustfa Kabi+5 more
wiley +1 more source