Results 161 to 170 of about 454,859 (358)

GLYCOGEN SYNTHASE DEFICIENCY: METABOLIC AND TISSUE STUDIES [PDF]

open access: bronze, 1984
Rosalind S. Brown   +2 more
openalex   +1 more source

Lupus Nephritis: Glycogen Synthase Kinase 3β Promotion of Renal Damage Through Activation of the NLRP3 Inflammasome in Lupus‐Prone Mice

open access: yesArthritis & Rheumatology, 2015
Jijun Zhao   +7 more
semanticscholar   +1 more source

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

open access: yesSmall Methods, EarlyView.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai   +9 more
wiley   +1 more source

Upregulation of ST3GAL5 predicts suppression of malignant biological behavior in bladder cancer

open access: yesUroPrecision, EarlyView.
Abstract Background Bladder cancer (BLCA) is the most prevalent malignancy in the urinary tract system, while ST3GAL5 is a protein‐coding gene that catalyzes the formation of ganglioside monosialodihexosylganglioside 3 (GM3) synthase. GM3 synthase has been reported to significantly influence the malignant process of various cancers.
Song Ou‐Yang   +3 more
wiley   +1 more source

Nuclear glycogen synthase — an artifact of preparation

open access: yesFEBS Letters, 1980
Joseph Larner   +2 more
openaire   +3 more sources

A non‐hormonal reversible contraceptive targeting GSK3α, a protein kinase, essential for epididymal sperm maturation

open access: yesAndrology, EarlyView.
Abstract Background and objectives Epididymal transit renders key competence to mammalian spermatozoa for fertilizing eggs. Generally, the two paralogs of glycogen synthase kinase 3, GSK3α and GSK3β, functionally overlap except in testis and sperm. We showed that GSK3α is essential for epididymal sperm maturation and fertilization.
Mustfa Kabi   +5 more
wiley   +1 more source

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