Results 171 to 180 of about 448,615 (401)

Glycogen is a neutral cargo of bulk autophagy in Komagataella phaffii

open access: yesAutophagy Reports
Glycogen is a primary cellular energy store in numerous eukaryotes. Its biosynthesis is a main strategy to cope with forthcoming starvation. During starvation, glycogen is processed in the cytosol or delivered for degradation to animal lysosomes or yeast
Nimna V. Wijewantha, Taras Y. Nazarko
doaj   +1 more source

Importance of proteins and mitochondrial changes as freshness indicators in fish muscle post‐mortem

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Evaluating protein and mitochondrial alterations post‐mortem can contribute to determining correlations between fish‐processing parameters and ultimate fish muscle quality. The myofibrillar protein alteration during rigor mortis directly affects the texture of fish muscle.
Nima Hematyar   +2 more
wiley   +1 more source

Imaging cytochrome C oxidase and FoF1-ATP synthase in mitochondrial cristae of living human cells by FLIM and superresolution microscopy [PDF]

open access: yesarXiv, 2017
Cytochrome C oxidase and FoF1-ATP synthase constitute complex IV and V, respectively, of the five membrane-bound enzymes in mitochondria comprising the respiratory chain. These enzymes are located in the inner mitochondrial membrane (IMM), which exhibits large invaginations called cristae.
arxiv  

Downregulation of forkhead box O1 (FOXO1) acetylation ameliorates cognitive dysfunction by inhibiting endoplasmic reticulum stress‐regulated neuronal apoptosis in APP/PS1 transgenic mice

open access: yesNeuroprotection, EarlyView.
Downregulation of the expression of silent information regulator sirtuin 1 (SIRT1) exacerbates neuronal degeneration and loss by activating forkhead box O1 (FOXO1) acetylation and promoting endoplasmic reticulum stress (ERSA)‐mediated apoptosis in aging.
Nan Zhang   +20 more
wiley   +1 more source

Purification and Characterization of a cAMP- and Ca2+-Calmodulin-Independent Glycogen Synthase Kinase from Porcine Renal Cortex [PDF]

open access: yes, 1984
We recently reported the partial purification of a cAMP-independent and Ca2+-calmodulin-independent glycogen synthase kinase from porcine renal cortex (Schlender, K. K., Beebe, S. J., and Reimann, E. M. (1981) Cold Spring Harbor Conf. Cell Proliferation,
Beebe, Stephen J.   +2 more
core   +1 more source

Concentration‐Based Analysis of Metal‐Induced Tau Fibrillar versus non‐fibrillar Aggregation: Implications for Neurotoxicity in Alzheimer's Disease

open access: yesChemistryOpen, EarlyView.
Tau protein aggregation and fibrillation have been examined in relationship to three metal ions in this study. The research was conducted to see the effects of Zn2+, Cu2+ and Fe3+ ions at different concentrations on tau′s conformation, cytotoxicity in SH‐SY5Y cells, and free thiol levels.
Mahzad Irandoust   +6 more
wiley   +1 more source

Dendrobium officinale polysaccharide attenuates type 2 diabetes mellitus via the regulation of PI3K/Akt-mediated glycogen synthesis and glucose metabolism

open access: yesJournal of Functional Foods, 2018
This study aimed to explore the therapeutic effects of Dendrobium officinale polysaccharide (DOP), an active ingredient isolated from the water extract of Dendrobium officinale, in streptozotocin (STZ)-induced type 2 diabetic BALB/c mice and its ...
Kaiping Wang   +8 more
doaj  

Isolation of a Unique Monoterpene Diperoxy Dimer From Ziziphora clinopodioides subsp. bungeana Together With Triterpenes With Antidiabetic Properties

open access: yesPhytochemical Analysis, EarlyView.
ABSTRACT Introduction Ziziphora clinopodioides subsp. bungeana (Juz.) Rech.f. is used in traditional medicine for various purposes. Previous phytochemical studies focused on phenolic compounds, but triterpenoids were almost overlooked. Objective The study focused on the isolation of compounds with dual antidiabetic activity from the aerial parts of Z ...
Milan Malaník   +11 more
wiley   +1 more source

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