Results 291 to 300 of about 149,215 (350)

Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders. [PDF]

Sci Transl Med
Ullman JC, Mellem KT, Xi Y, Ramanan V, Merritt H, Choy R, Gujral T, Young LEA, Blake K, Tep S, Homburger JR, O'Regan A, Ganesh S, Wong P, Satterfield TF, Lin B, Situ E, Yu C, Espanol B, Sarwaikar R, Fastman N, Tzitzilonis C, Lee P, Reiton D, Morton V, Santiago P, Won W, Powers H, Cummings BB, Hoek M, Graham RR, Chandriani SJ, Bainer R, DePaoli-Roach AA, Roach PJ, Hurley TD, Sun RC, Gentry MS, Sinz C, Dick RA, Noonberg SB, Beattie DT, Morgans DJ, Green EM.   +43 more
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Sex differences in insulin regulation of skeletal muscle glycogen synthase and changes during weight loss and exercise in adults. [PDF]

Obesity (Silver Spring)
Ryan AS, Li G, McMillin S, Ortmeyer HK.
europepmc   +1 more source

Small molecule inhibition of glycogen synthase I reduces muscle glycogen content and improves biomarkers in a mouse model of Pompe disease.

Am J Physiol Endocrinol Metab
Gaspar RC, Sakuma I, Nasiri A, Hubbard BT, LaMoia TE, Leitner BP, Tep S, Xi Y, Green EM, Ullman JC, Petersen KF, Shulman GI.   +11 more
europepmc   +1 more source

Expression of Concern "Glycogen synthase kinase-3β inhibition attenuates the development of bleomycin-induced lung injury". [PDF]

Int J Immunopathol Pharmacol
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Nuclear Glycogen and Glycogen Synthase Kinase 3

Biochemical and Biophysical Research Communications, 1998
Glycogen is the principal storage form of glucose in animal cells. It accumulates in electron-dense cytoplasmic granules and is synthesized by glycogen synthase (GS), the rate-limiting enzyme of glycogen deposition. Glycogen synthase kinase-3 (GSK-3) is a protein kinase that phosphorylates GS.
M, Ragano-Caracciolo, W K, Berlin, M W, Miller, J A, Hanover   +3 more
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Glycogen and glycogen synthase from pig leucocytes

International Journal of Biochemistry, 1979
Abstract 1. 1. Pig polymorphonuclears and lymphocytes show a lower glycogen content than human leucocytes. 2. 2. The glycogen synthase activity from pig leucocytes has the same value as that from human leucocytes. 3. 3. Two forms of glycogen synthase interconvertible by phosphorylation-dephosphorylation reactions are present in pig ...
F, Pegueroles, R, Cussó
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INSULIN AND GLYCOGEN SYNTHASE

Diabetes, 1972
The present status of the molecular nature of the enzyme glycogen synthase from rabbit skeletal muscle is reviewed. It is shown that per 90,000 Dalton subunit there are six phosphorylatable sites and six sulfhydryl groups. No pyridoxal phosphate is present.
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Glycogen Synthase and Glycogen Synthase Kinases

1981
Publisher Summary This chapter focuses on properties and other biochemical and physiological processes related to glycogen synthase and glycogen synthase kinases. The reversible covalent modification of proteins appears to be one of the fundamental mechanisms that have evolved to regulate the inherent properties of enzyme molecules.
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