Results 311 to 320 of about 448,615 (401)

High‐Frequency Mutations in TP53, AXIN1, CTNNB1, and KRAS, and Polymorphisms in JAK1 Genes Among Mongolian HCC Patients

Cancer Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background Mongolia has the highest incidence of liver cancer worldwide, largely driven by a high prevalence of hepatitis virus infections. Mutations in oncogenes and tumor suppressor genes provide valuable insights into the molecular mechanisms of hepatocellular carcinoma (HCC). Aims This study aimed to investigate the prevalence of mutations
Nomin Bold, Khurelsukh Buyanbat, Ariya Enkhtuya, Nomin Myagmar, Gerelsuren Batbayar, Zolzaya Sandag, Dolgion Damdinbazar, Nomuun Oyunbat, Tuul Boldbaatar, Ankhbayar Enkhbaatar, Gan‐Erdene Baatarjav, Taivan Nanzaddorj, Tsendsuren Oyunsuren, Gantulga Davaakhuu   +13 more
wiley   +1 more source

Glycogen synthase kinase-3 inhibition and insulin enhance proliferation and inhibit maturation of human iPSC-derived cardiomyocytes via TCF and FOXO signaling. [PDF]

Stem Cell Reports
Yuan Q, Verbueken D, Dinani R, Kim R, Schoger E, Morsink CD, Simkooei SA, Kemna LJM, Hjortnaes J, Kuster DWD, Boon RA, Zelarayan LC, van der Velden J, Buikema JW.   +13 more
europepmc   +1 more source

SCF/β-TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner

Molecular and Cellular Biology, 2011
P. Rada, A. I. Rojo, S. Chowdhry, M. McMahon, J. Hayes, A. Cuadrado   +5 more
semanticscholar   +1 more source

Age‐Dependent Effects of Muscle Resting Calcium on Fasting Blood Glucose: Implications for Prediabetes Risk

Endocrinology, Diabetes &Metabolism, Volume 8, Issue 3, May 2025.
This correlation study shows that elevated resting calcium levels in skeletal muscle are associated with an increased risk of developing diabetes in an age‐dependent manner. ABSTRACT Background and Aims Skeletal muscle is the primary site for insulin‐mediated glucose uptake and is critical in maintaining whole‐body glucose homeostasis.
Eshwar R. Tammineni, Lourdes Figueroa, Michael Fill, Sheila Riazi, Carlo Manno   +4 more
wiley   +1 more source

Large Scale Protein Production and Activity Assay Protocols for Human Glycogen Synthase-Glycogenin Complex

, 2023
Marr L, Biswas D, Sakamoto K, Zeqiraj E.
europepmc   +1 more source

Nutraceutical Potential of Anthocyanins: A Comprehensive Treatise

Food Science &Nutrition, Volume 13, Issue 5, May 2025.
Anthocyanins reduce LDL, VLDL, TGs, and TC via improved GBA and upregulation of ATP6 V0C, ZO‐1, and ATG4D expression. The WHO/FAO suggested that 2.5 mg/kg/day of grape‐skin extracts of anthocyanins is safe, and China recommended that 50 mg/day of anthocyanins is safe for consumption.
Ahmad Mujtaba Noman, Muhammad Tauseef Sultan, Muhammad Maaz, Aimen Mazhar, Naima Tariq, Muhammad Imran, Muzzamal Hussain, Ahmed Mujtaba, Mohamed A. Abdelgawad, Ehab M. Mostafa, Mohammed M. Ghoneim, Samy Selim, Entessar Al Jbawi   +12 more
wiley   +1 more source

Targeted inhibition of glycogen synthase kinase-3 using 9-ING-41 (elraglusib) enhances CD8 T-cell-reactivity against neuroblastoma cells. [PDF]

Sci Rep
Markovska A, Somers K, Guillaume J, Melief J, Mazar AP, Schmitt DM, Schipper HS, Boes M.   +7 more
europepmc   +1 more source

Biogenesis of Organelles and Membrane Proteins. [PDF]

, 1988
Harmey, Matthew A., Neupert, Walter, Nicholson, Donald W., Stuart, Rosemary A.   +3 more
core   +1 more source

Tubulin Polymerization Promoting Proteins: Functional Diversity With Implications in Neurological Disorders

Journal of Neuroscience Research, Volume 103, Issue 5, May 2025.
A family of human proteins, encoded by Tubulin Polymerization Promoting Proteins (TPPP), is highly conserved across species. TPPP displays remarkable functional diversity and is implicated in various neurological disorders. Image created with BioRender.com.
Paloma J. Diaz, Qian Shi, Priscilla Y. McNeish, Swati Banerjee   +3 more
wiley   +1 more source

Sex differences in insulin regulation of skeletal muscle glycogen synthase and changes during weight loss and exercise in adults. [PDF]

Obesity (Silver Spring)
Ryan AS, Li G, McMillin S, Ortmeyer HK.
europepmc   +1 more source