Results 331 to 340 of about 448,615 (401)

Production of yeast cell wall polysaccharides‐β‐glucan and chitin by using food waste substrates: Biosynthesis, production, extraction, and purification methods

Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 3, May 2025.
Abstract Food waste causes significant environmental and economic challenges worldwide, prompting many nations to prioritize its reduction and recycling. As a nutrient‐rich material containing vitamins, proteins, and carbohydrates, it serves as a promising substrate for the cultivation of single‐cell microorganisms like yeast.
Deniz Günal‐Köroğlu, Gulsah Karabulut, Fariddudin Mohammadian, Aslı Can Karaca, Esra Capanoglu, Tuba Esatbeyoglu   +5 more
wiley   +1 more source

Effects of Glucagon-Like Peptide 1 on the Kinetics of Glycogen Synthase a in Hepatocytes from Normal and Diabetic Rats*

, 1998
Marı́a I. López-Delgado, Mònica Morales, María Luisa Villanueva‐Peñacarrillo, Willy Malaisse, Isabel Valverde   +4 more
openalex   +1 more source

Peroxiredoxin Tsa1 Regulates the Activity of Trehalose Metabolism‐Related Enzymes During Wine Yeast Biomass Propagation

Microbial Biotechnology, Volume 18, Issue 5, May 2025.
Trehalose metabolism is key for yeast stress tolerance, but its regulation in industrial conditions is unclear. This study shows that deleting TSA1 in Saccharomyces cerevisiae increases trehalose accumulation and the activity of its synthesis and degradation enzymes, enhancing desiccation resistance.
Víctor Garrigós, Emilia Matallana, Cecilia Picazo, Agustín Aranda   +3 more
wiley   +1 more source

Glycogen synthase kinase-3 is essential for T_regdevelopment and function

Kandasamy M, Andrew HF, Raza IG, Mitchell R, Borsa M, Attar M, Clarke AJ.   +6 more
europepmc   +1 more source

Glycogen synthase kinase 3β: the nexus of chemoresistance, invasive capacity, and cancer stemness in pancreatic cancer. [PDF]

Cancer Drug Resist
Uehara M, Domoto T, Takenaka S, Takeuchi O, Shimasaki T, Miyashita T, Minamoto T.   +6 more
europepmc   +1 more source

NAT10 Knockdown Improves Cisplatin Sensitivity in Non‐Small Cell Lung Cancer by Inhibiting the TRIM44/PI3K/AKT Pathway

Thoracic Cancer, Volume 16, Issue 9, May 2025.
NAT10 expression is elevated in DDP‐resistant NSCLC cells. The enhanced expression of NAT10 leads to an increase in TRIM44 expression through an ac4C‐dependent mechanism, which subsequently activates the PI3K/AKT pathway. This activation, in turn, reduces the sensitivity of NSCLC cells to DDP, inhibits apoptosis, and fosters cell proliferation ...
Qi Sun, Xiansong Yang, Ye Wang, Kejia Yang, Yuan Weng   +4 more
wiley   +1 more source

Glycogen Synthase Kinase-3 Beta (GSK3β) as a Potential Drug Target in Regulating Osteoclastogenesis: An Updated Review on Current Evidence. [PDF]

Biomolecules
Wong SK.
europepmc   +1 more source

Transferrin Receptor Promotes Endometrial Cancer Proliferation by Activating the Iron‐Dependent PI3K/AKT/mTOR Signaling Pathway

Cancer Science, Volume 116, Issue 5, Page 1352-1365, May 2025.
TFRC may serve as a critical prognostic indicator for risk assessment in EC patients and propose TFRC as a promising therapeutic target to impede EC progression. The upregulation of TFRC‐mediated iron absorption facilitated the proliferation of EC, suggesting that iron chelators had the potential to be a promising therapeutic agent for the treatment of
Yufei Yang, Ying Ning, Yu Chen, Tian Tian, Xinyan Gao, Yan Kong, Ke Lei, Zhumei Cui   +7 more
wiley   +1 more source

Carnitine supplementation improves insulin sensitivity and skeletal muscle acetylcarnitine formation in patients with type 2 diabetes

Diabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2864-2877, May 2025.
Abstract Aim/Hypothesis Recently, we reported that increasing free carnitine availability resulted in elevated skeletal muscle acetylcarnitine concentrations and restored metabolic flexibility in individuals who have impaired glucose tolerance. Metabolic flexibility is defined as the capacity to switch from predominantly fat oxidation while fasted to ...
Yvonne M. H. Op den Kamp‐Bruls, Yvo J. M. Op den Kamp, Pandichelvam Veeraiah, Ruben Zapata Perez, Esther Phielix, Bas Havekes, Gert Schaart, Esther Kornips, Bart R. B. Berendsen, Ashraf Virmani, Joachim E. Wildberger, Riekelt H. Houtkooper, Matthijs K. C. Hesselink, Patrick Schrauwen, Vera B. Schrauwen‐Hinderling   +14 more
wiley   +1 more source

The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5‐Independent Manner

Experimental Dermatology, Volume 34, Issue 5, May 2025.
Overview of the TRPM5‐independent effects of TPPO in human sebocytes. TPPO moderately increases sebaceous lipogenesis via activating Akt ➔ DGAT2 and EGFR signalling and deeply influences the immune phenotype of human sebocytes, shaping it to a chiefly anti‐inflammatory direction. ABSTRACT Transient receptor potential melastatin 5 (TRPM5) ion channel is
Dorottya Ádám, József Arany, Kinga Fanni Tóth, Orsolya Pető, Tamara Nyitrai, Balázs István Tóth, Szilárd Póliska, Christos C. Zouboulis, Attila Oláh   +8 more
wiley   +1 more source